STAT2 Is a Pervasive Cytokine Regulator due to Its Inhibition of STAT1 in Multiple Signaling Pathways

Response to interferons and antibacterial innate immunity in the absence of tyrosine‐phosphorylated STAT1

(2016) Andrea Majoros et al.   EMBO REPORTS

Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity

(2015) Kiyoshi Hirahara et al.   IMMUNITY

Kinase inhibition, competitive binding and proteasomal degradation: resolving the molecular function of the suppressor of cytokine signaling (SOCS) proteins

(2015) Edmond M. Linossi et al.   IMMUNOLOGICAL REVIEWS

Disease-Promoting Effects of Type I Interferons in Viral, Bacterial, and Coinfections

(2015) Sophia Davidson et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+T cells

(2015) Chi-Keung Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human IFNAR2 deficiency: Lessons for antiviral immunity

(2015) Christopher J. A. Duncan et al.   Science Translational Medicine

Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

(2014) Wei Xu et al.   Cell Host & Microbe

STAT1  Is Not Dominant Negative and Is Capable of Contributing to Gamma Interferon-Dependent Innate Immunity

(2014) C. Semper et al.   MOLECULAR AND CELLULAR BIOLOGY

STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling

(2014) Andreas Begitt et al.   NATURE IMMUNOLOGY

Dominant-negative activity of the STAT3-Y705F mutant depends on the N-terminal domain

(2013) Anne Mohr et al.   Cell Communication and Signaling

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

(2013) HyeonJoo Cheon et al.   EMBO JOURNAL

Heterozygosity for the Y701C STAT1 mutation in a multiplex kindred with multifocal osteomyelitis

(2013) O. Hirata et al.   HAEMATOLOGICA

Evidence against a Role for β-Arrestin1 in STAT1 Dephosphorylation and the Inhibition of Interferon-γ Signaling

(2013) Christin Pelzel et al.   MOLECULAR CELL

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis

(2013) W. Alazawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT2 deficiency and susceptibility to viral illness in humans

(2013) S. Hambleton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Analysis of Murine Macrophages Infected with Different Toxoplasma Strains Identifies Novel Regulation of Host Signaling Pathways

(2013) Mariane B. Melo et al.   PLoS Pathogens

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

STAT3 mutations correlated with hyper-IgE syndrome lead to blockage of IL-6/STAT3 signalling pathway

(2012) Jianxin He et al.   JOURNAL OF BIOSCIENCES

The Role of Signal Transducer and Activator of Transcription-2 in the Interferon Response

(2012) Håkan C. Steen et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFN 

(2011) A. Begitt et al.   BLOOD

Interpreting mixed signals: the cell's cytokine conundrum

(2011) Greg M Delgoffe et al.   CURRENT OPINION IN IMMUNOLOGY

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Innate responses to Toxoplasma gondii in mice and humans

(2011) Reed Pifer et al.   TRENDS IN PARASITOLOGY

A Novel Role for IFN-Stimulated Gene Factor 3II in IFN-  Signaling and Induction of Antiviral Activity in Human Cells

(2010) A. N. Morrow et al.   JOURNAL OF IMMUNOLOGY

Molecular Basis for the Recognition of Phosphorylated STAT1 by Importin α5

(2010) Jonathan Nardozzi et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

(2010) Daniel J. Gough et al.   PLOS BIOLOGY

Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations

(2008) N. Wenta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA