Identification of new key genes for type 1 diabetes through construction and analysis of protein-protein interaction networks based on blood and pancreatic islet transcriptomes

CXCR3, CXCL10 and type 1 diabetes

(2014) Alessandro Antonelli et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Macrophages and  -cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes

(2014) J. Diana et al.   EMBO Molecular Medicine

A human immunodeficiency caused by mutations in the PIK3R1 gene

(2014) Marie-Céline Deau et al.   JOURNAL OF CLINICAL INVESTIGATION

The prediction of candidate genes for cervix related cancer through gene ontology and graph theoretical approach

(2014) V. Hindumathi et al.   Molecular BioSystems

Juvenile Idiopathic Arthritis Subtype- and Sex-specific Associations with Genetic Variants in the PSMA6/PSMC6/PSMA3 Gene Cluster

(2014) Tatjana Sjakste et al.   Pediatrics and Neonatology

Construction and Analysis of the Protein-Protein Interaction Networks Based on Gene Expression Profiles of Parkinson's Disease

(2014) Hindol Rakshit et al.   PLoS One

The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes

(2013) Monika Ryba-Stanisławowska et al.   MEDIATORS OF INFLAMMATION

Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data

(2012) Min Li et al.   BMC BIOINFORMATICS

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

(2012) R. Bergholdt et al.   DIABETES

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

(2012) Jae-Hoon Chang et al.   NATURE IMMUNOLOGY

Detecting overlapping protein complexes in protein-protein interaction networks

(2012) Tamás Nepusz et al.   NATURE METHODS

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

(2012) Décio L. Eizirik et al.   PLoS Genetics

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

Understanding type 1 diabetes through genetics: advances and prospects

(2011) Constantin Polychronakos et al.   NATURE REVIEWS GENETICS

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

The Shc locus regulates insulin signaling and adiposity in mammals

(2010) Alexey A. Tomilov et al.   AGING CELL

Exendin-4 Suppresses Src Activation and Reactive Oxygen Species Production in Diabetic Goto-Kakizaki Rat Islets in an Epac-Dependent Manner

(2010) E. Mukai et al.   DIABETES

Genetics of Type 1 Diabetes: What's Next?

(2010) F. Pociot et al.   DIABETES

Specific gene expression signature associated with development of autoimmune type-I diabetes using whole-blood microarray analysis

(2010) F Reynier et al.   GENES AND IMMUNITY

Blockade of interleukin 1 in type 1 diabetes mellitus

(2010) Thomas Mandrup-Poulsen et al.   Nature Reviews Endocrinology

Dynamic modularity in protein interaction networks predicts breast cancer outcome

(2009) Ian W Taylor et al.   NATURE BIOTECHNOLOGY

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

CORUM: the comprehensive resource of mammalian protein complexes—2009

(2009) Andreas Ruepp et al.   NUCLEIC ACIDS RESEARCH

Integrated network analysis platform for protein-protein interactions

(2008) Jianmin Wu et al.   NATURE METHODS

Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases

(2008) Monika Ray et al.   GENOME BIOLOGY