Pathway Analysis Revealed Potential Diverse Health Impacts of Flavonoids that Bind Estrogen Receptors

Isoflavone formononetin from red propolis acts as a fungicide against Candida sp

(2016) Michelline Viviane Marques das Neves et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Applying network analysis and Nebula (neighbor-edges based and unbiased leverage algorithm) to ToxCast data

(2016) Hao Ye et al.   ENVIRONMENT INTERNATIONAL

Estrogenic effects of flavonoid components in Xiaoyao powder

(2016) J.H. Chen et al.   GENETICS AND MOLECULAR RESEARCH

Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

(2015) Heng Luo et al.   BMC BIOINFORMATICS

Molecular Docking to Identify Associations Between Drugs and Class I Human Leukocyte Antigens for Predicting Idiosyncratic Drug Reactions

(2015) Heng Luo et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Interaction of Isoflavones with the BCRP/ABCG2 Drug Transporter

(2015) Kristin Bircsak et al.   CURRENT DRUG METABOLISM

Low Levels of a Urinary Biomarker of Dietary Polyphenol Are Associated with Substantial Cognitive Decline over a 3-Year Period in Older Adults: The Invecchiare in Chianti Study

(2015) Montserrat Rabassa et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Curcumin and Apigenin - novel and promising therapeutics against chronic neuroinflammation in Alzheimer′s disease

(2015) Gerald Münch et al.   Neural Regeneration Research

A Systematic Review of the Efficacy of Bioactive Compounds in Cardiovascular Disease: Phenolic Compounds

(2015) Oscar Rangel-Huerta et al.   Nutrients

Inhibition of hepatitis B virus replication by quercetin in human hepatoma cell lines

(2015) Zhikui Cheng et al.   VIROLOGICA SINICA

Measuring exposure to the polyphenol metabolome in observational epidemiologic studies: current tools and applications and their limits

(2014) Raul Zamora-Ros et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

(2014) Hui Wen Ng et al.   BMC BIOINFORMATICS

The new biology of estrogen-induced apoptosis applied to treat and prevent breast cancer

(2014) V Craig Jordan   ENDOCRINE-RELATED CANCER

Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis

(2014) Ashley E. Frakes et al.   NEURON

Inhibitory Activity of the Isoflavone Biochanin A on Intracellular Bacteria of Genus Chlamydia and Initial Development of a Buccal Formulation

(2014) Leena Hanski et al.   PLoS One

Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein

(2014) Huixiao Hong et al.   TOXICOLOGICAL SCIENCES

Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes

(2013) Jie Shen et al.   BMC BIOINFORMATICS

High Anthocyanin Intake Is Associated With a Reduced Risk of Myocardial Infarction in Young and Middle-Aged Women

(2013) Aedín Cassidy et al.   CIRCULATION

The Association Between Dietary Flavonoid and Lignan Intakes and Incident Type 2 Diabetes in European Populations: The EPIC-InterAct study

(2013) R. Zamora-Ros et al.   DIABETES CARE

The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs

(2013) Yan Li et al.   Expert Opinion on Drug Metabolism & Toxicology

Estrogen receptor-β regulates human tryptophan hydroxylase-2 through an estrogen response element in the 5′ untranslated region

(2013) Ryoko Hiroi et al.   JOURNAL OF NEUROCHEMISTRY

Flavonoids, Flavonoid Subclasses and Breast Cancer Risk: A Meta-Analysis of Epidemiologic Studies

(2013) Chang Hui et al.   PLoS One

Evaluation of Estrogenic Potential of Flavonoids Using a Recombinant Yeast Strain and MCF7/BUS Cell Proliferation Assay

(2013) Flávia A. Resende et al.   PLoS One

EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity

(2013) Jie Shen et al.   TOXICOLOGICAL SCIENCES

Effects of quercetin on the proliferation of breast cancer cells and expression of survivin in vitro

(2013) XIAO-HUI DENG et al.   Experimental and Therapeutic Medicine

Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults

(2012) Marjorie L McCullough et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Flavonoids in Cancer Prevention

(2012) Eun-Jung Park et al.   Anti-Cancer Agents in Medicinal Chemistry

A pathway profile-based method for drug repositioning

(2012) Hao Ye et al.   CHINESE SCIENCE BULLETIN

Comparison of Methods for Competitive Tests of Pathway Analysis

(2012) Marina Evangelou et al.   PLoS One

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Study of drug function based on similarity of pathway fingerprint

(2012) Hao Ye et al.   Protein & Cell

Estrogen Signaling and Cardiovascular Disease

(2011) Elizabeth Murphy   CIRCULATION RESEARCH

Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease

(2011) Robert J. Williams et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tumor necrosis factor-α activates estrogen signaling pathways in endometrial epithelial cells via estrogen receptor α

(2011) Ilaria Gori et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Antioxidant activity of phenolic and flavonoid compounds in some medicinal plants of India

(2011) R.K. Choudhary et al.   NATURAL PRODUCT RESEARCH

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

(2011) Amanda M Haidet-Phillips et al.   NATURE BIOTECHNOLOGY

Antidiabetic activity of isoquercetin in diabetic KK -Ay mice

(2011) Rui Zhang et al.   Nutrition & Metabolism

The Accurate Prediction of Protein Family from Amino Acid Sequence by Measuring Features of Sequence Fragments

(2010) Huixiao Hong et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

HIT: linking herbal active ingredients to targets

(2010) H. Ye et al.   NUCLEIC ACIDS RESEARCH

Flavonoids as anti-inflammatory agents

(2010) Mauro Serafini et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Regulation of estrogen receptor beta activity and implications in health and disease

(2009) Elin Swedenborg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Viral Myocarditis

(2009) Toshitaka Yajima et al.   CIRCULATION

Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity

(2009) Elvira Haas et al.   CIRCULATION RESEARCH

Dietary flavonoid intake and risk of cancer in postmenopausal women: The Iowa Women's Health Study

(2008) Gretchen J. Cutler et al.   INTERNATIONAL JOURNAL OF CANCER

Intake of flavonoids and risk of cancer in Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study

(2008) Jaakko Mursu et al.   INTERNATIONAL JOURNAL OF CANCER

Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer

(2006) V Craig Jordan   BRITISH JOURNAL OF PHARMACOLOGY