The Transactivation Domains of the p53 Protein

Characterization of the p300 Taz2–p53 TAD2 Complex and Comparison with the p300 Taz2–p53 TAD1 Complex

(2015) Lisa M. Miller Jenkins et al.   BIOCHEMISTRY

PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites

(2015) O Mortusewicz et al.   ONCOGENE

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

(2014) Grzegorz Popowicz et al.   CELL CYCLE

Extended String Binding Mode of the Phosphorylated Transactivation Domain of Tumor Suppressor p53

(2014) Masahiko Okuda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inappropriate p53 activation during development induces features of CHARGE syndrome

(2014) Jeanine L. Van Nostrand et al.   NATURE

Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex

(2013) K. Murakami et al.   SCIENCE

Ubiquitin and Proteasomes in Transcription

(2012) Fuqiang Geng et al.   Annual Review of Biochemistry

The Mediator complex and transcription elongation

(2012) Ronald C. Conaway et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

p53 N-terminal phosphorylation: a defining layer of complex regulation

(2012) L. M. M. Jenkins et al.   CARCINOGENESIS

Competitive Binding between Dynamic p53 Transactivation Subdomains to Human MDM2 Protein

(2012) Bing Shan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail

(2012) John P. Rowell et al.   STRUCTURE

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages

(2011) D. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein

(2010) Chul Won Lee et al.   BIOCHEMISTRY

p53 activates transcription by directing structural shifts in Mediator

(2010) Krista D Meyer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation

(2010) C. W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation†

(2009) Lisa M. Miller Jenkins et al.   BIOCHEMISTRY

Mapping the Interactions of the p53 Transactivation Domain with the KIX Domain of CBP†

(2009) Chul Won Lee et al.   BIOCHEMISTRY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

(2009) Sridharan Rajagopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

(2009) D P Teufel et al.   ONCOGENE

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

(2009) J. C. Ferreon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation

(2009) Hanqiao Feng et al.   STRUCTURE

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

(2008) Christopher J Oldfield et al.   BMC GENOMICS

Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage

(2008) A. M. Gamper et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

(2008) M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence

(2008) T. M. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for caspase 2 and PIDD in the process of p53-mediated apoptosis

(2008) N. Baptiste-Okoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Recognition of Phosphorylated Transactivation Domains of p53 by Different p300 Domains

(2007) Smarajit Polley et al.   JOURNAL OF MOLECULAR BIOLOGY