Novel Chemical Ligands to Ebola Virus and Marburg Virus Nucleoproteins Identified by Combining Affinity Mass Spectrometry and Metabolomics Approaches

Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening

(2015) Shanshan Qin et al.   ANALYTICA CHIMICA ACTA

Targeted Metabolomics Approach To Detect the Misuse of Steroidal Aromatase Inhibitors in Equine Sports by Biomarker Profiling

(2015) George Ho Man Chan et al.   ANALYTICAL CHEMISTRY

Dose-dependent targeted knockout methodology combined with deep structure elucidation strategies for Chinese licorice chemical profiling

(2015) Zhenzuo Jiang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology

(2015) Binta Diémé et al.   JOURNAL OF PROTEOME RESEARCH

Global health security: the wider lessons from the west African Ebola virus disease epidemic

(2015) David L Heymann et al.   LANCET

West African Ebola Epidemic after One Year — Slowing but Not Yet under Control

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Development of a method to screen and isolate potential xanthine oxidase inhibitors from Panax japlcus var via ultrafiltration liquid chromatography combined with counter-current chromatography

(2015) Sainan Li et al.   TALANTA

A Ligand-observed Mass Spectrometry Approach Integrated into the Fragment Based Lead Discovery Pipeline

(2015) Xin Chen et al.   Scientific Reports

Assembly of the Ebola Virus Nucleoprotein from a Chaperoned VP35 Complex

(2015) Robert N. Kirchdoerfer et al.   Cell Reports

An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions

(2015) Daisy W. Leung et al.   Cell Reports

A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein

(2015) Michinori Kakisaka et al.   PLoS Pathogens

Insight into the Ebola virus nucleocapsid assembly mechanism: crystal structure of Ebola virus nucleoprotein core domain at 1.8 Å resolution

(2015) Shishang Dong et al.   Protein & Cell

Screening for selective inhibitors of xanthine oxidase from Flos Chrysanthemum using ultrafiltration LC–MS combined with enzyme channel blocking

(2014) Hui-Peng Song et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells

(2014) Reed S. Shabman et al.   mBio

Identification of Inhibitors of the Antibiotic-Resistance Target New Delhi Metallo-β-lactamase 1 by both Nanoelectrospray Ionization Mass Spectrometry and Ultrafiltration Liquid Chromatography/Mass Spectrometry Approaches

(2013) Xin Chen et al.   ANALYTICAL CHEMISTRY

Glycyrrhizic Acid Suppresses the Development of Precancerous Lesions via Regulating the Hyperproliferation, Inflammation, Angiogenesis and Apoptosis in the Colon of Wistar Rats

(2013) Rehan Khan et al.   PLoS One

Toll-Like Receptor 7 Agonists: Chemical Feature Based Pharmacophore Identification and Molecular Docking Studies

(2013) Hui Yu et al.   PLoS One

Antiviral Activity of Glycyrrhizin against Hepatitis C Virus In Vitro

(2013) Yoshihiro Matsumoto et al.   PLoS One

An ultrafiltration high-performance liquid chromatography coupled with diode array detector and mass spectrometry approach for screening and characterising tyrosinase inhibitors from mulberry leaves

(2012) Zhenzhong Yang et al.   ANALYTICA CHIMICA ACTA

Investigation of the Human Brain Metabolome to Identify Potential Markers for Early Diagnosis and Therapeutic Targets of Alzheimer’s Disease

(2012) Stewart F. Graham et al.   ANALYTICAL CHEMISTRY

Glycyrrhizin as antiviral agent against Hepatitis C Virus

(2011) Usman A Ashfaq et al.   Journal of Translational Medicine

Analysis of protein-ligand interactions by fluorescence polarization

(2011) Ana M Rossi et al.   Nature Protocols

Glycyrrhizin Exerts Antioxidative Effects in H5N1 Influenza A Virus-Infected Cells and Inhibits Virus Replication and Pro-Inflammatory Gene Expression

(2011) Martin Michaelis et al.   PLoS One

Development of an Ultrafiltration-Liquid Chromatography/Mass Spectrometry (UF-LC/MS) Based Ligand-Binding Assay and an LC/MS Based Functional Assay forMycobacterium tuberculosisShikimate Kinase

(2010) Vanisree Mulabagal et al.   ANALYTICAL CHEMISTRY

Screening Natural Products for Inhibitors of Quinone Reductase-2 Using Ultrafiltration LC−MS

(2010) Yongsoo Choi et al.   ANALYTICAL CHEMISTRY

Characterization of the Ebola virus nucleoprotein-RNA complex

(2010) T. Noda et al.   JOURNAL OF GENERAL VIROLOGY

Identification of influenza A nucleoprotein as an antiviral target

(2010) Richard Y Kao et al.   NATURE BIOTECHNOLOGY

Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation

(2010) Hongmei Cao et al.   PHARMACOLOGICAL RESEARCH