The recombined cccDNA produced using minicircle technology mimicked HBV genome in structure and function closely

Increasing the minicircle DNA purity using an enhanced triplex DNA technology to eliminate DNA contaminants

(2015) Xiaohu H Hou et al.   Molecular Therapy-Methods & Clinical Development

The global burden of liver disease: The major impact of China

(2014) Fu-Sheng Wang et al.   HEPATOLOGY

Recombinant Covalently Closed Circular Hepatitis B Virus DNA Induces Prolonged Viral Persistence in Immunocompetent Mice

(2014) Zhihua Qi et al.   JOURNAL OF VIROLOGY

Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses

(2014) Christian Königer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correction: Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

(2014) Huan Yan et al.   eLife

The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo

(2014) Su-Ru Lin et al.   Molecular Therapy-Nucleic Acids

Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes

(2013) Yi Ni et al.   GASTROENTEROLOGY

An Efficient Antiviral Strategy for Targeting Hepatitis B Virus Genome Using Transcription Activator-Like Effector Nucleases

(2013) Jieliang Chen et al.   MOLECULAR THERAPY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Alpha-Interferon Suppresses Hepadnavirus Transcription by Altering Epigenetic Modification of cccDNA Minichromosomes

(2013) Fei Liu et al.   PLoS Pathogens

A SELEX-Screened Aptamer of Human Hepatitis B Virus RNA Encapsidation Signal Suppresses Viral Replication

(2011) Hui Feng et al.   PLoS One

The Pre-S2 Domain of the Hepatitis B Virus Is Dispensable for Infectivity but Serves a Spacer Function for L-Protein-Connected Virus Assembly

(2010) Y. Ni et al.   JOURNAL OF VIROLOGY

A robust system for production of minicircle DNA vectors

(2010) Mark A Kay et al.   NATURE BIOTECHNOLOGY

Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner

(2010) Josef Köck et al.   PLoS Pathogens

Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection

(2009) Richard N. Cohen et al.   JOURNAL OF CONTROLLED RELEASE

Control of cccDNA function in hepatitis B virus infection

(2009) Massimo Levrero et al.   JOURNAL OF HEPATOLOGY

Production and Function of the Cytoplasmic Deproteinized Relaxed Circular DNA of Hepadnaviruses

(2009) H. Guo et al.   JOURNAL OF VIROLOGY

Initiation of hepatitis B virus genome replication and production of infectious virus following delivery in HepG2 cells by novel recombinant baculovirus vector

(2008) J. Lucifora et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis B viruses: Reverse transcription a different way

(2008) Michael Nassal   VIRUS RESEARCH