An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity

A prospective study of erythrocyte polyunsaturated fatty acid, weight gain, and risk of becoming overweight or obese in middle-aged and older women

(2015) Lu Wang et al.   EUROPEAN JOURNAL OF NUTRITION

The Impact of the Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People: Scientific and Policy Aspects and the International Network of Centers for Genetics, Nutrition and Fitness for Health

(2015) Artemis P. Simopoulos   Journal of Nutrigenetics and Nutrigenomics

Arachidonic acid impairs hypothalamic leptin signaling and hepatic energy homeostasis in mice

(2015) Licai Cheng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

(2015) Melina Claussnitzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endogenous ω-3 Polyunsaturated Fatty Acid Production Confers Resistance to Obesity, Dyslipidemia, and Diabetes in Mice

(2014) Jie Li et al.   MOLECULAR ENDOCRINOLOGY

The Fat from Frozen Mammals Reveals Sources of Essential Fatty Acids Suitable for Palaeolithic and Neolithic Humans

(2014) José L. Guil-Guerrero et al.   PLoS One

Update on cardiometabolic health effects of ω-3 fatty acids

(2013) Daan Kromhout et al.   CURRENT OPINION IN LIPIDOLOGY

Dietary Linoleic Acid Elevates the Endocannabinoids 2-AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet

(2013) Anita Røyneberg Alvheim et al.   LIPIDS

Dietary Omega-3 Fatty Acid Deficiency and High Fructose Intake in the Development of Metabolic Syndrome, Brain Metabolic Abnormalities, and Non-Alcoholic Fatty Liver Disease

(2013) Artemis Simopoulos   Nutrients

Genetic Adaptation of Fatty-Acid Metabolism: A Human-Specific Haplotype Increasing the Biosynthesis of Long-Chain Omega-3 and Omega-6 Fatty Acids

(2012) Adam Ameur et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prenatal fatty acid status and child adiposity at age 3 y: results from a US pregnancy cohort

(2011) Sara MA Donahue et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

(2011) Rasika A Mathias et al.   BMC GENETICS

Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome

(2011) Susan Sergeant et al.   BRITISH JOURNAL OF NUTRITION

Inflammation and mesenchymal stem cell aging

(2011) Günter Lepperdinger   CURRENT OPINION IN IMMUNOLOGY

Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk

(2011) Artemis P Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE

Metabolic responses to high-fat diets rich in n-3 or n-6 long-chain polyunsaturated fatty acids in mice selected for either high body weight or leanness explain different health outcomes

(2011) Karin Nuernberg et al.   Nutrition & Metabolism

Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet

(2010) Remko S. Kuipers et al.   BRITISH JOURNAL OF NUTRITION

Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism

(2010) D R Schwinkendorf et al.   INTERNATIONAL JOURNAL OF OBESITY

A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations

(2010) Florence Massiera et al.   JOURNAL OF LIPID RESEARCH

Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat

(2009) Z. Hassanali et al.   DIABETES OBESITY & METABOLISM

Leptin Receptor Polymorphisms Interact with Polyunsaturated Fatty Acids to Augment Risk of Insulin Resistance and Metabolic Syndrome in Adults

(2009) Catherine M. Phillips et al.   JOURNAL OF NUTRITION

Effect of dietary fat on endocannabinoids and related mediators: Consequences on energy homeostasis, inflammation and mood

(2009) Sebastiano Banni et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Anti-obesity effects of long-chain omega-3 polyunsaturated fatty acids

(2009) J. D. Buckley et al.   Obesity Reviews

Endocannabinoids selectively enhance sweet taste

(2009) R. Yoshida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss

(2008) Dolores Parra et al.   APPETITE

Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine

(2008) Andreas Artmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Efficacy and Safety of Rimonabant for Improvement of Multiple Cardiometabolic Risk Factors in Overweight/Obese Patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program

(2008) L. Van Gaal et al.   DIABETES CARE

Brain Regulation of Appetite and Satiety

(2008) Rexford S. Ahima et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in Cardiovascular Disease and Other Chronic Diseases

(2008) Artemis P. Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE