Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells

Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer

(2015) Constanze Buhrmann et al.   BIOCHEMICAL PHARMACOLOGY

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer

(2015) Mehdi Shakibaei et al.   BMC CANCER

The Interaction between Epigenetics, Nutrition and the Development of Cancer

(2015) Karen Bishop et al.   Nutrients

Sirtuin-1 (SIRT1) Is Required for Promoting Chondrogenic Differentiation of Mesenchymal Stem Cells

(2014) Constanze Buhrmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT

(2014) Constanze Buhrmann et al.   PLoS One

Small molecule SIRT1 activators for the treatment of aging and age-related diseases

(2014) Basil P. Hubbard et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oncogene withdrawal engages the immune system to induce sustained cancer regression

(2014) Stephanie C Casey et al.   Journal for ImmunoTherapy of Cancer

Encapsulated human hepatocellular carcinoma cells by alginate gel beads as an in vitro metastasis model

(2013) Xiao-xi Xu et al.   EXPERIMENTAL CELL RESEARCH

Calorie restriction and sirtuins revisited

(2013) L. Guarente   GENES & DEVELOPMENT

Sorting out functions of sirtuins in cancer

(2013) M Roth et al.   ONCOGENE

Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner

(2013) Qing Yang et al.   PLoS One

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

(2013) B. P. Hubbard et al.   SCIENCE

Epigenetic and genetic features of 24 colon cancer cell lines

(2013) D Ahmed et al.   Oncogenesis

Resveratrol enhances radiation sensitivity in prostate cancer by inhibiting cell proliferation and promoting cell senescence and apoptosis

(2012) Yujiang Fang et al.   CANCER SCIENCE

Resveratrol-mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation

(2012) Raffaele Frazzi et al.   INTERNATIONAL JOURNAL OF CANCER

Sirt-1 Is Required for the Inhibition of Apoptosis and Inflammatory Responses in Human Tenocytes

(2012) Franziska Busch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Modulates Interleukin-1β-induced Phosphatidylinositol 3-Kinase and Nuclear Factor κB Signaling Pathways in Human Tenocytes

(2012) Franziska Busch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms

(2012) Yuhan Tang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells

(2012) Z Wang et al.   ONCOGENE

Clinical trials of resveratrol

(2011) Ketan R. Patel et al.   Annals of the New York Academy of Sciences

Small-Molecule Allosteric Activators of Sirtuins

(2011) David A. Sinclair et al.   Annual Review of Pharmacology and Toxicology

Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis

(2011) H. Yuan et al.   BLOOD

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Sirtuin 1 in malignant transformation: Friend or foe?

(2011) Yujiang Fang et al.   CANCER LETTERS

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol’s Effects on Insulin Action in Rats

(2011) Colette M. Knight et al.   DIABETES

Predictors of Postoperative Mortality, Morbidity, and Long-Term Survival After Palliative Resection in Patients With Colorectal Cancer

(2011) Andrew P. Stillwell et al.   DISEASES OF THE COLON & RECTUM

Immune microenvironments in solid tumors: new targets for therapy

(2011) S. L. Shiao et al.   GENES & DEVELOPMENT

Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells

(2011) Mehdi Shakibaei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

NF-κB Signaling Pathway, Inflammation and Colorectal Cancer

(2010) Soly Wang et al.   Cellular & Molecular Immunology

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

SirT1 Is an Inhibitor of Proliferation and Tumor Formation in Colon Cancer

(2009) Neha Kabra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol suppresses interleukin-1β-induced inflammatory signaling and apoptosis in human articular chondrocytes: Potential for use as a novel nutraceutical for the treatment of osteoarthritis

(2008) Mehdi Shakibaei et al.   BIOCHEMICAL PHARMACOLOGY

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis

(2008) Rui-Hong Wang et al.   MOLECULAR CELL

Resveratrol addiction: To die or not to die

(2008) Mehdi Shakibaei et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

(2008) Ron Firestein et al.   PLoS One