Article
Chemistry, Inorganic & Nuclear
Emily C. Monkcom, Hidde A. Negenman, Eduard Masferrer-Rius, Martin Lutz, Shengfa Ye, Eckhard Bill, Robertus J. M. Klein Gebbink
Summary: In this study, two new bioinspired N,N,O phenolate ligands were synthesized and their coordination chemistry with zinc(II) and iron(II) was explored. BenzImNNO readily formed homoleptic bisligated complexes, while the increased steric bulk of Im(Ph2)NNO promoted the formation of dinuclear complexes. The robustness of the ligand's coordination mode was demonstrated during oxidative transformations.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Shawn M. Moore, Chen Sun, Jennifer L. Steele, Ellen M. Laaker, Arnold L. Rheingold, Linda H. Doerrer
Summary: There is a strong interest in MnOHx moieties due to the stepwise changes in O-H bonds with Mn oxidation state changes. The reactivity of aquo-derived ligands, {MOHx}, is influenced by the electronic character of other ligands. Preparation of mononuclear Mn complexes with all O-donors is rare despite oxygen coordination being prevalent in biological systems.
Article
Chemistry, Inorganic & Nuclear
Eva Zahradnikova, Ivana Cisarova, Bohuslav Drahos
Summary: In this work, the preparation and characterization of three manganese(II) complexes with structurally-new pyridine-based macrocyclic ligands are presented. X-ray diffraction analysis confirmed a coordination number seven with a close to pentagonal bipyramid geometry for all complexes studied.
Article
Multidisciplinary Sciences
Wenjun Yang, Ivan Yu Chernyshov, Robin K. A. van Schendel, Manuela Weber, Christian Muller, Georgy A. Filonenko, Evgeny A. Pidko
Summary: In this study, a highly efficient manganese pincer pre-catalyst was reported, displaying high TOF values (up to 41,000 h(-1)) and stability (TON up to 200,000) at loadings as low as 5-200 ppm. The crucial role of catalyst activation step for the catalytic performance and stability of the system was highlighted, with activation using hydride donor promoters significantly improving catalytic performance and eliminating induction times. Manganese-based hydrogenation catalysts are shown to be sensitive to high temperatures, but this pre-catalyst offers a promising alternative.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Nicolas Lentz, Martin Albrecht
Summary: This article reports on a highly efficient iridium-based catalyst for formic acid dehydrogenation. The catalyst exhibits high turnover frequencies and turnover numbers, and is characterized by its low cost and easy accessibility, making it suitable for industrial applications.
Review
Biochemistry & Molecular Biology
Loukiani Savva, Savvas N. Georgiades
Summary: G-quadruplexes, a family of tetraplex helical nucleic acid topologies, have shown potential for anticancer research due to their presence in functionally-important regions of the human genome and their ability to exert anticancer effects. Despite only a few lead compounds progressing to clinical trials, recent advancements in the field have created conditions for further development of drug candidates targeting G-quadruplexes.
Article
Chemistry, Multidisciplinary
Pragya Arora, Sikha Gupta, Sai Kumari Vechalapu, Rakesh Kumar, Ayushi Awasthi, Sathyapriya Senthil, Shweta Khanna, Dharmaraja Allimuthu, Apparao Draksharapu
Summary: In the presence of mCPBA, the reaction of [(L)MnII]2+ generated a putative MnV=O species, which was capable of performing aromatic hydroxylation of Cl-benzoic acid derived from mCPBA at room temperature. The formation of [(L)MnIII(m-Cl-salicylate)]+ was shown not to be a dead end for catalysis, and a plausible mechanism for the formation of [(L)MnV(O)-m-Cl-salicylate)]+ from [(L)MnIII(m-Cl-salicylate)]+ was proposed. The characterized transient [(L)MnV(O)-m-Cl-salicylate)]+ exhibited high reactivity for oxygen atom transfer reactions.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Review
Crystallography
Jian-Xun Liu, Shi-Lin Mei, Xian-He Chen, Chang-Jiang Yao
Summary: Near-infrared (NIR) emissive metal complexes with bridging ligands have shown potential applications in various fields due to their tunability and stability. By designing the molecular structure effectively, the desired performance of NIR emitting metal complexes with bridging ligands can be easily achieved.
Article
Biochemistry & Molecular Biology
Paula Daniela Mestizo, Diana M. Narvaez, Jesus Alberto Pinzon-Ulloa, Daniela Torres Di Bello, Sebastian Franco-Ulloa, Mario A. Macias, Helena Groot, Gian Pietro Miscione, Leopoldo Suescun, John J. Hurtado
Summary: The study synthesized eight novel metal complexes and evaluated their anticarcinogenic potential at the cellular level. The results showed that compounds 2 and 6 exhibited good anticancer effects on HeLa cells.
Article
Biology
Man Ren, Yuan Yang, Dan Li, Nannan Zhao, Yuping Wang, Yongning Zhou
Summary: In this study, the mechanisms of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) against gastric cancer were explored through network pharmacology and molecular docking. The results revealed that PGG exerts a therapeutic efficacy on gastric cancer by multiple targets (MAPK14, BCL2L1, and VEGFA) and pathways (MAPK, PD-L1 checkpoint, PI3K-Akt, Ras, and HIF-1 pathways).
Article
Engineering, Chemical
Pin-Wen Huang, Cong-Zhi Wang, Qun-Yan Wu, Jian-Hui Lan, Zhi-Fang Chai, Wei-Qun Shi
Summary: Separation of minor actinides (MAs) from lanthanides (Ln) is a crucial and challenging step in advanced nuclear waste treatment. The development of water-soluble back-extraction ligands is considered as a feasible alternative method for efficient An(III)/Ln(III) separation. Therefore, it is important to theoretically investigate the mechanism behind the selective back-extraction of An(III).
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Inorganic & Nuclear
Pavel A. Demakov, Konstantin A. Kovalenko, Alexander N. Lavrov, Vladimir P. Fedin
Summary: Two new metal-organic frameworks based on flexible odabco ligands were synthesized and characterized. They possess cationic 2D networks filled with perchlorate anions and dioxane solvent in the interlayer space. Gas adsorption properties and magnetization characteristics were investigated.
Article
Chemistry, Physical
Sabrina M. da Silva, Adriana C. Pinheiro, Miria T. da Costa, Thiago C. G. Alves, Robson S. Oliboni, Rafael Stieler, Adriana C. A. Casagrande, O. L. Casagrande Jr
Summary: This article describes the synthesis and reactivity of a new set of chromium(III) complexes supported by pyrrolide-imine ligands with pendant O-, S-, and N-donor groups. The catalytic performances of these complexes in the oligomerization and polymerization of ethylene were investigated, and the nature of the pendant group was found to have a significant impact on the catalytic activities. High selectivity for oligomers was achieved with chromium complexes containing O-donor groups, while those with sulfur-donor groups primarily produced polymers.
MOLECULAR CATALYSIS
(2022)
Article
Chemistry, Inorganic & Nuclear
L. L. de Oliveira, F. Batista, R. S. Oliboni, A. C. A. Casagrande, R. Stieler, O. L. Casagrande Jr
Summary: A series of chromium complexes were synthesized and characterized, showing different catalytic activities and selectivities in ethylene oligomerization, mainly controlled by the electronic effects of ligands. The DFT calculations revealed important energetic and orbital information of the complexes, aiding in understanding the catalytic performance.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Zhen-Xin Zhao, Gao-Li Zhao, Bing-Xue Lu, Hao-Hao Zhang, Gao-Sheng Li, Li-Fu Wang, Cheng-Xing Cui, Ling-Bo Qu
Summary: Three new Cd-II coordination polymers with 2D and 3D structures have been synthesized, showing different topology networks including rob, zzx, and cem. The introduction of distinct ligands is favorable for constructing interpenetrated networks. Additionally, the luminescent properties of the compounds have been investigated and the electron transfer from metal to ligand in compound 3 has been confirmed by DFT calculations.
JOURNAL OF PHYSICAL ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Wafa A. Bawazir, Maymoona A. Al-Mahmood, Rawan S. Almalki, Ghadi F. Alofi, Raghad S. Alharbi, Zoya Zaheer
Summary: This study investigates the interaction between sulfathiazole and three types of surfactants using UV-visible spectroscopy and conductivity measurements. The results show that the critical micelle concentration of cationic and anionic surfactants decreases with increasing sulfathiazole concentration, while the interaction with non-ionic surfactant is weak.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Musaad K. Aleid, Khalid N. Alharbi, Mona A. Aljufareen, Areej S. Aloliwi, Alhanouf K. Almutairi, Rahaf S. Alsaif, Nada K. Alshayeb, Mohammed S. Almoiqli
Summary: This study assessed the levels of trihalomethane compounds in the water network of Riyadh city and identified the factors influencing their formation. The concentrations of trihalomethane compounds were within the permissible limits, indicating the water's safety for human consumption. The presence of bromide ions, organic carbon, free chlorine, and pH values were found to affect trihalomethane formation.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Said Arhzaf, Jamal Houssaini, Mohammed Naciri Bennani, Marwa Alaqarbeh, Mohammed Bouachrine
Summary: The study shows that Mg-Al hydrotalcite catalysts intercalated with acetate and carbonate anions exhibit superior catalytic activity in the aldol condensation reaction between furfural and acetone. The optimal reaction conditions are at 90 degrees C for 2 hours, achieving conversion rates of over 98% with high selectivity towards F2A for the acetate catalyst.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Uyen-Chi Nguyen Le, Ngoc Xuan Dat Mai, Kieu-Minh Le, Hoang Anh Vu, Huynh-Nhu Thi Tran, Tan Le Hoang Doan
Summary: This study aimed to enhance the bioavailability of rosmarinic acid, a bioactive compound with high anticancer activity, by encapsulating it in tetrasulfide-based porous organosilica nanoparticles. The synthesized nanoparticles were small in size and had a high surface area and an average pore diameter. The nanoparticles showed effective accumulation in cancer cells without toxicity to normal cells. Treatment with rosmarinic acid-containing nanoparticles resulted in significant cell death in cancer cells. Overall, these findings suggest that the synthesized nanoparticles can enhance the pharmacological effects of rosmarinic acid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jiamin Qi, Hengxi Zhu, Tianyu Yang, Xingyuan Wang, Zixuan Wang, Xiaoli Lei, Bin Li, Wenmin Qian
Summary: This study synthesized a novel iron-biochar adsorbent using the iron content in red mud to remove heavy metals from wastewater. The adsorbent showed excellent removal efficiency and sustainability. This method addresses both industrial waste recovery and heavy metal adsorption issues.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Bo Yi, Li Zhang, Haiyang Zhou
Summary: Plasma protein binding plays a crucial role in the pharmacokinetics and pharmacodynamics of therapeutic bioactive materials. In this study, the interaction of nordentatin, a member of coumarins, with human alpha-1 acid glycoprotein (AGP) was investigated, and the anticancer potency of nordentatin against human colorectal cancer cells was evaluated. The results showed that nordentatin binds to AGP through a static quenching mechanism and exhibits inhibitory effects on the growth of HCT-116 cells by increasing intracellular ROS and [Ca2+] levels and triggering apoptosis-related gene overexpression. Therefore, nordentatin could be a promising plant-based therapy for colorectal cancer.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qiming Pang, Cui Wang, Bangtao Li, Suli Zhang, Jiaoyang Li, Shuo Gu, Xueyu Shi
Summary: This study evaluated the effects of resveratrol loaded in copolymer nanoparticles on cerebral ischemia/reperfusion (I/R) injury in rats. The results showed that RES.CP.NPs could have neuroprotective effects through their antioxidant and anti-inflammatory activities, leading to improved neurological disability scores and decreased oxidative stress levels.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Maryam Rachmawati Sumitra, Lung-Ching Chen, Wei-Chen Tsai, Muhamad Ansar, Bashir Lawal, Ntlotlang Mokgautsi, Jih-Hwa Guh, Alexander T. H. Wu, Hsu-Shan Huang
Summary: Tetraheterocyclic compounds derived from natural sources and contemporary pharmaceuticals have shown promise as multitarget therapeutic agents. In this study, a series of synthesized compounds were evaluated for their potential in breast cancer treatment. Compounds 18 and 20 demonstrated significant antiproliferative activity against breast cancer cell lines and their mode of action was revealed through molecular docking simulations.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Mohammad Khosravani, Mohsen Dehghani Ghanatghestani, Farid Moeinpour, Hossein Parvaresh
Summary: The aim of removing Pb(II) from water is to minimize the potential harm posed by toxic metals to both human health and the environment. A covalent organic framework adsorbent called TFPOTDB-SO3H was developed with excellent properties such as high repeatability, selectivity, and easy solid-liquid separation. The adsorbent showed impressive capability of adsorbing Pb(II) and effective removal of it from a solution with various ions, suggesting its potential for effectively adsorbing and removing Pb(II) heavy metal ions from wastewater.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Ashraf H. Farha, Mohamed S. Shams, Hasna A. Alali, Zakia H. Alhashem, Shehab A. Mansour, Shrouq H. Aleithan, Ragab A. Elsad
Summary: The current study examines the dielectric and thermal properties of transformer oil incorporated with Mn0.5 Zn0.5 Fe2O4 nanoparticles. The results show that the addition of Mn-Zn ferrite NPs improves the dielectric constant, dissipation factor, AC breakdown voltage, and convective heat transfer of the nanofluid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Limin Hou, Zongpei Jiang, Minqi Ye, Xueyan Sun, Kexin Liu, Yifan Zhu, Xiaoyu Wang, Liangzhu Chen, Ruiheng Gu, Binghu Fang
Summary: The excessive accumulation of antibiotic residue in animal-derived foods poses a threat to health. Therefore, it is necessary to establish a rapid, simple, effective, safe, and highly sensitive method for detecting lincomycin residues. By using a pre-column derivatization method on high-performance liquid chromatography equipped with ultraviolet, the UV absorption of lincomycin is improved, allowing for detection and quantification.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Kun Tang, Xin-Xin Wang, Jin-Jin Zhao, Ning Ren, Jian-Jun Zhang
Summary: This study reports the synthesis, crystal structures, and thermal degradation properties of three new rare earth coordination compounds. Compounds 1-3 exhibit binuclear structures which can form chain-like structures via hydrogen bonding. Compound 2 shows potential application value in the orange-red luminescence region.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Seoyoun Yang, Eunbi Yu, See-Hyoung Park, Sae Woong Oh, Kitae Kwon, Su Bin Han, Soo Hyun Kang, Jung Hyun Lee, Heejun Ha, Minkyung Song, Jae Youl Cho, Jongsung Lee
Summary: This study investigated the effects of blue light on the hypodermis and found that it has antiadipogenic properties by reducing lipid accumulation and downregulating the expression of adipogenic genes. Blue light also increased the phosphorylation of PPAR gamma and TRPV1, suggesting its anti-adipogenic effect through these signaling pathways.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Abdul Nasir, Abdul Waheed Khan, Hamid Rafiq Khattak, Abdus Samad, Sami Ullah, Haroon Khan, Muhammad Faheem, Qian Bai
Summary: This study evaluated the effects of isoxazolone derivatives on cisplatin-induced neuropathy in a rat model. The results showed that isoxazolone derivatives effectively reversed mechanical allodynia, similar to the known therapeutic agent pregabalin. Molecular docking analysis indicated that isoxazolone derivatives have strong binding affinity for relevant receptors and potential inhibitory activity against relevant signaling pathways. This study has innovative implications for the treatment of cisplatin-induced neuropathic pain.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Shahid Wahab, Haroon Muhammad Ali, Maham Khan, Tariq Khan, Chandran Krishnaraj, Soon-Il Yun
Summary: In this study, we synthesized chitosan nanoparticles, silver nanoparticles, and chitosan/silver nanocomposites using aqueous ginger extract as a green approach. These nanomaterials showed significant antibacterial properties and low toxicity. Furthermore, the nanomaterials conjugated with tobramycin demonstrated enhanced antibacterial efficacy and exhibited interactions with Pseudomonas aeruginosa.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
