PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7

PTEN Functions by Recruitment to Cytoplasmic Vesicles

(2015) Adam Naguib et al.   MOLECULAR CELL

The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting

(2014) F. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Endocytic Rabs in membrane trafficking and signaling

(2013) Johannes Numrich et al.   BIOLOGICAL CHEMISTRY

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Functional analysis of the protein phosphatase activity of PTEN

(2012) Xiaoqun Catherine Zhang et al.   BIOCHEMICAL JOURNAL

Toward a Comprehensive Characterization of a Human Cancer Cell Phosphoproteome

(2012) Houjiang Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Cullin-3 regulates late endosome maturation

(2012) J. Huotari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN Protein Phosphatase Activity Correlates with Control of Gene Expression and Invasion, a Tumor-Suppressing Phenotype, But Not with AKT Activity

(2012) P. Tibarewal et al.   Science Signaling

Regulation of the EGF Transcriptional Response by Endocytic Sorting

(2012) B. Brankatschk et al.   Science Signaling

WWP2 is an E3 ubiquitin ligase for PTEN

(2011) Subbareddy Maddika et al.   NATURE CELL BIOLOGY

The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7

(2010) Mirjana Nordmann et al.   CURRENT BIOLOGY

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

(2010) Lai Kuan Goh et al.   JOURNAL OF CELL BIOLOGY

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

(2009) Phillip A. Vanlandingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase

(2009) Subbareddy Maddika et al.   NATURE CELL BIOLOGY

The Protein Phosphatase Activity of PTEN Regulates Src Family Kinases and Controls Glioma Migration

(2008) N. Dey et al.   CANCER RESEARCH

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE