C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

(2015) Eduardo Bonavita et al.   CELL

Complement Is a Central Mediator of Radiotherapy-Induced Tumor-Specific Immunity and Clinical Response

(2015) Laura Surace et al.   IMMUNITY

Complement in therapy and disease

(2015) Joost P.M. Melis et al.   MOLECULAR IMMUNOLOGY

Emerging and Novel Functions of Complement Protein C1q

(2015) Lubna Kouser et al.   Frontiers in Immunology

Genetic and Pharmacologic Inhibition of Complement Impairs Endothelial Cell Function and Ablates Ovarian Cancer Neovascularization

(2015) Selene Nunez-Cruz et al.   NEOPLASIA

New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape

(2014) Deepak Mittal et al.   CURRENT OPINION IN IMMUNOLOGY

Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice

(2014) P Macor et al.   LEUKEMIA

Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer

(2014) Saskia Meyer et al.   mAbs

Mutant p53 Reprograms TNF Signaling in Cancer Cells through Interaction with the Tumor Suppressor DAB2IP

(2014) Giulio Di Minin et al.   MOLECULAR CELL

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

(2014) Sandra S. McAllister et al.   NATURE CELL BIOLOGY

C1q as a unique player in angiogenesis with therapeutic implication in wound healing

(2014) F. Bossi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocrine Effects of Tumor-Derived Complement

(2014) Min Soon Cho et al.   Cell Reports

Complement anaphylatoxins as immune regulators in cancer

(2014) Eli T. Sayegh et al.   Cancer Medicine

A Dramatic Increase of C1q Protein in the CNS during Normal Aging

(2013) A. H. Stephan et al.   JOURNAL OF NEUROSCIENCE

The role of complement in mAb-based therapies of cancer

(2013) Ronald P. Taylor et al.   METHODS

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Why is melanoma so metastatic?

(2013) Russell R. Braeuer et al.   Pigment Cell & Melanoma Research

Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?

(2013) L. M. Coussens et al.   SCIENCE

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

Role of C5b-9 complement complex and response gene to complement-32 (RGC-32) in cancer

(2012) Sonia I. Vlaicu et al.   IMMUNOLOGIC RESEARCH

gC1qR Expression in Normal and Pathologic Human Tissues

(2012) Francine R. Dembitzer et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Anaphylatoxin C5a Creates a Favorable Microenvironment for Lung Cancer Progression

(2012) Leticia Corrales et al.   JOURNAL OF IMMUNOLOGY

Opposing Roles for Complement Component C5a in Tumor Progression and the Tumor Microenvironment

(2012) L. Gunn et al.   JOURNAL OF IMMUNOLOGY

The Complement System at the Embryo Implantation Site: Friend or Foe?

(2012) R. Bulla et al.   Frontiers in Immunology

The C1q Family of Proteins: Insights into the Emerging Non-Traditional Functions

(2012) Berhane Ghebrehiwet et al.   Frontiers in Immunology

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Complement and non-complement activating functions of C1q: A prototypical innate immune molecule

(2011) Annapurna Nayak et al.   Innate Immunity

Complement in the brain

(2011) Robert Veerhuis et al.   MOLECULAR IMMUNOLOGY

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

The non-classical functions of the classical complement pathway recognition subcomponent C1q

(2010) Annapurna Nayak et al.   IMMUNOLOGY LETTERS

Dual role of complement in tumour growth and metastasis (Review)

(2010) Stover   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

An Alternative Role of C1q in Cell Migration and Tissue Remodeling: Contribution to Trophoblast Invasion and Placental Development

(2010) C. Agostinis et al.   JOURNAL OF IMMUNOLOGY

Overdiagnosis in Cancer

(2010) H. G. Welch et al.   JNCI-Journal of the National Cancer Institute

Cancer and the Complement Cascade

(2010) M. J. Rutkowski et al.   MOLECULAR CANCER RESEARCH

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Harnessing the immune response to treat cancer

(2010) H J Steer et al.   ONCOGENE

Unwelcome Complement

(2009) M. M. Markiewski et al.   CANCER RESEARCH

Is complement good or bad for cancer patients? A new perspective on an old dilemma

(2009) Maciej M. Markiewski et al.   TRENDS IN IMMUNOLOGY

Decidual endothelial cells express surface-bound C1q as a molecular bridge between endovascular trophoblast and decidual endothelium

(2008) Roberta Bulla et al.   MOLECULAR IMMUNOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Cancer exploiting complement: a clue or an exception?

(2008) Bruce E Loveland et al.   NATURE IMMUNOLOGY

Modulation of the antitumor immune response by complement

(2008) Maciej M Markiewski et al.   NATURE IMMUNOLOGY