Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease

(2016) Vittorio Calderone et al.   GASTROENTEROLOGY

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

(2015) Einav Shoshan et al.   NATURE CELL BIOLOGY

Targeting the translation machinery in cancer

(2015) Mamatha Bhat et al.   NATURE REVIEWS DRUG DISCOVERY

Genetics of familial melanoma: 20 years afterCDKN2A

(2015) Lauren G. Aoude et al.   Pigment Cell & Melanoma Research

Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy

(2015) Claudia Wellbrock et al.   Pigment Cell & Melanoma Research

Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle

(2015) Valeria Giangarrà et al.   PLoS One

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

(2015) Diego Ploper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperactivated endolysosomal trafficking in melanoma

(2015) Direna Alonso-Curbelo et al.   Oncotarget

Cytoplasmic Polyadenylation Element Binding Proteins in Development, Health, and Disease

(2014) Maria Ivshina et al.   Annual Review of Cell and Developmental Biology

RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway

(2014) Direna Alonso-Curbelo et al.   CANCER CELL

Cpeb4-Mediated Translational Regulatory Circuitry Controls Terminal Erythroid Differentiation

(2014) Wenqian Hu et al.   DEVELOPMENTAL CELL

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

(2014) T. Afroz et al.   GENES & DEVELOPMENT

Robustly detecting differential expression in RNA sequencing data using observation weights

(2014) Xiaobei Zhou et al.   NUCLEIC ACIDS RESEARCH

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Fishful thinking: the rise and fall of MITF in melanoma

(2013) Colin R. Goding   Pigment Cell & Melanoma Research

The CPEB-family of proteins, translational control in senescence and cancer

(2012) Gonzalo Fernández-Miranda et al.   AGEING RESEARCH REVIEWS

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Melanoma: from mutations to medicine

(2012) H. Tsao et al.   GENES & DEVELOPMENT

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

(2012) Michael Krauthammer et al.   NATURE GENETICS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Translational control by changes in poly(A) tail length: recycling mRNAs

(2012) Laure Weill et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reviewing the somatic genetics of melanoma: from current to future analytical approaches

(2012) Ken Dutton-Regester et al.   Pigment Cell & Melanoma Research

MicroRNA-550a Acts as a Pro-Metastatic Gene and Directly Targets Cytoplasmic Polyadenylation Element-Binding Protein 4 in Hepatocellular Carcinoma

(2012) Qi Tian et al.   PLoS One

Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage

(2011) Elias Pavlopoulos et al.   CELL

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

Key contribution of CPEB4-mediated translational control to cancer progression

(2011) Elena Ortiz-Zapater et al.   NATURE MEDICINE

Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway

(2011) A E Thurber et al.   ONCOGENE

GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells

(2011) Delphine Javelaud et al.   Pigment Cell & Melanoma Research

The three M’s: melanoma, microphthalmia-associated transcription factor and microRNA

(2011) Rachel E. Bell et al.   Pigment Cell & Melanoma Research

An Integrated Approach to Uncover Drivers of Cancer

(2010) Uri David Akavia et al.   CELL

Control of Tumorigenesis and Chemoresistance by the DEK Oncogene

(2010) E. Riveiro-Falkenbach et al.   CLINICAL CANCER RESEARCH

Meiosis requires a translational positive loop where CPEB1 ensues its replacement by CPEB4

(2010) Ana Igea et al.   EMBO JOURNAL

Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control

(2010) Isabel Novoa et al.   NATURE CELL BIOLOGY

The discovery of the microphthalmia locus and its gene, Mitf

(2010) Heinz Arnheiter   Pigment Cell & Melanoma Research

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Melanoma Proliferation and Chemoresistance Controlled by the DEK Oncogene

(2009) M. S. Khodadoust et al.   CANCER RESEARCH

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants

(2009) Peter J. A. Cock et al.   NUCLEIC ACIDS RESEARCH

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

A Combinatorial Code for CPE-Mediated Translational Control

(2008) Maria Piqué et al.   CELL

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Microphthalmia-associated Transcription Factor RegulatesRAB27AGene Expression and Controls Melanosome Transport

(2008) Christine Chiaverini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spindle-localized CPE-mediated translation controls meiotic chromosome segregation

(2008) Carolina Eliscovich et al.   NATURE CELL BIOLOGY