Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

Dissecting the roles of human BUB1 in the spindle assembly checkpoint

(2015) M. Vleugel et al.   JOURNAL OF CELL SCIENCE

Sequential Multisite Phospho-Regulation of KNL1-BUB3 Interfaces at Mitotic Kinetochores

(2015) Mathijs Vleugel et al.   MOLECULAR CELL

Joined at the hip: kinetochores, microtubules, and spindle assembly checkpoint signaling

(2015) Carlos Sacristan et al.   TRENDS IN CELL BIOLOGY

Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint

(2015) Gang Zhang et al.   Nature Communications

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint

(2015) Katharina Overlack et al.   eLife

PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing

(2014) Antonio Espert et al.   JOURNAL OF CELL BIOLOGY

The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C

(2014) Daisuke Izawa et al.   NATURE

Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

(2014) Wilco Nijenhuis et al.   NATURE CELL BIOLOGY

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

(2014) Joo Seok Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

(2014) Tiziana Lischetti et al.   Nature Communications

KI Motifs of Human Knl1 Enhance Assembly of Comprehensive Spindle Checkpoint Complexes around MELT Repeats

(2013) Veronica Krenn et al.   CURRENT BIOLOGY

Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation

(2013) Mathijs Vleugel et al.   JOURNAL OF CELL BIOLOGY

A minimal number of MELT repeats supports all the functions of KNL1 in chromosome segregation

(2013) Gang Zhang et al.   JOURNAL OF CELL SCIENCE

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

(2013) T. Kruse et al.   JOURNAL OF CELL SCIENCE

Catalytic Assembly of the Mitotic Checkpoint Inhibitor BubR1-Cdc20 by a Mad2-Induced Functional Switch in Cdc20

(2013) Joo Seok Han et al.   MOLECULAR CELL

Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling

(2013) Ivana Primorac et al.   eLife

BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

(2013) P. Xu et al.   Biology Open

Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint

(2012) Lindsey A. Shepperd et al.   CURRENT BIOLOGY

Phosphoregulation of Spc105 by Mps1 and PP1 Regulates Bub1 Localization to Kinetochores

(2012) Nitobe London et al.   CURRENT BIOLOGY

The Spindle Assembly Checkpoint

(2012) Pablo Lara-Gonzalez et al.   CURRENT BIOLOGY

Evolution and Function of the Mitotic Checkpoint

(2012) Mathijs Vleugel et al.   DEVELOPMENTAL CELL

Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments

(2012) Saskia J.E. Suijkerbuijk et al.   DEVELOPMENTAL CELL

Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction

(2012) Veronica Krenn et al.   JOURNAL OF CELL BIOLOGY

MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components

(2012) Yuya Yamagishi et al.   NATURE CELL BIOLOGY

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner

(2011) Pablo Lara-Gonzalez et al.   JOURNAL OF CELL SCIENCE

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

(2011) Emily A. Foley et al.   NATURE CELL BIOLOGY

Cubism and the cell cycle: the many faces of the APC/C

(2011) Jonathon Pines   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

(2010) Stefano Santaguida et al.   JOURNAL OF CELL BIOLOGY

BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/CCdc20 in Interphase

(2009) Liviu A. Malureanu et al.   DEVELOPMENTAL CELL

Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshin

(2009) Hanna Windecker et al.   EMBO REPORTS

Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1

(2009) S. Elowe et al.   JOURNAL OF CELL SCIENCE

Bub3p Facilitates Spindle Checkpoint Silencing in Fission Yeast

(2009) Vincent Vanoosthuyse et al.   MOLECULAR BIOLOGY OF THE CELL

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

(2008) Jakob Nilsson et al.   NATURE CELL BIOLOGY