Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

A Microtubule-Associated Zinc Finger Protein, BuGZ, Regulates Mitotic Chromosome Alignment by Ensuring Bub3 Stability and Kinetochore Targeting

(2014) Hao Jiang et al.   DEVELOPMENTAL CELL

BuGZ Is Required for Bub3 Stability, Bub1 Kinetochore Function, and Chromosome Alignment

(2014) Chad M. Toledo et al.   DEVELOPMENTAL CELL

A Protective Chaperone for the Kinetochore Adaptor Bub3

(2014) Zhejian Ji et al.   DEVELOPMENTAL CELL

Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores

(2014) S. Heinrich et al.   EMBO REPORTS

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint

(2014) N. London et al.   GENES & DEVELOPMENT

A Bub1–Mad1 interaction targets the Mad1–Mad2 complex to unattached kinetochores to initiate the spindle checkpoint

(2014) Mark W. Moyle et al.   JOURNAL OF CELL BIOLOGY

Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation

(2013) Carlos Conde et al.   EMBO JOURNAL

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

(2013) T. Kruse et al.   JOURNAL OF CELL SCIENCE

Catalytic Assembly of the Mitotic Checkpoint Inhibitor BubR1-Cdc20 by a Mad2-Induced Functional Switch in Cdc20

(2013) Joo Seok Han et al.   MOLECULAR CELL

Tracking spindle checkpoint signals from kinetochores to APC/C

(2013) Luying Jia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling

(2013) Ivana Primorac et al.   eLife

BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

(2013) P. Xu et al.   Biology Open

Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint

(2012) Lindsey A. Shepperd et al.   CURRENT BIOLOGY

Phosphoregulation of Spc105 by Mps1 and PP1 Regulates Bub1 Localization to Kinetochores

(2012) Nitobe London et al.   CURRENT BIOLOGY

The Spindle Assembly Checkpoint

(2012) Pablo Lara-Gonzalez et al.   CURRENT BIOLOGY

The Vertebrate Mitotic Checkpoint Protein BUBR1 Is an Unusual Pseudokinase

(2012) Saskia J.E. Suijkerbuijk et al.   DEVELOPMENTAL CELL

Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments

(2012) Saskia J.E. Suijkerbuijk et al.   DEVELOPMENTAL CELL

CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint

(2012) Yige Guo et al.   JOURNAL OF CELL BIOLOGY

Structure of the mitotic checkpoint complex

(2012) William C. H. Chao et al.   NATURE

MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components

(2012) Yuya Yamagishi et al.   NATURE CELL BIOLOGY

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting

(2012) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mad2 and Mad3 Cooperate to Arrest Budding Yeast in Mitosis

(2011) Derek T.C. Lau et al.   CURRENT BIOLOGY

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner

(2011) Pablo Lara-Gonzalez et al.   JOURNAL OF CELL SCIENCE

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

(2010) R. Gassmann et al.   GENES & DEVELOPMENT

Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition

(2010) Sheena D'Arcy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

(2010) Andrew J. Holland et al.   JOURNAL OF CELL BIOLOGY

Recruitment of Cdc20 to the Kinetochore Requires BubR1 but Not Mad2 in Drosophila melanogaster

(2010) D. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Kinetic Analysis of Mad2−Cdc20 Formation: Conformational Changes in Mad2 Are Catalyzed by a C-Mad2−Ligand Complex

(2009) Latesh Lad et al.   BIOCHEMISTRY

BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/CCdc20 in Interphase

(2009) Liviu A. Malureanu et al.   DEVELOPMENTAL CELL

Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding

(2009) Anita Kulukian et al.   DEVELOPMENTAL CELL

Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1

(2009) S. Elowe et al.   JOURNAL OF CELL SCIENCE

Bub3p Facilitates Spindle Checkpoint Silencing in Fission Yeast

(2009) Vincent Vanoosthuyse et al.   MOLECULAR BIOLOGY OF THE CELL

The Influence of Catalysis on Mad2 Activation Dynamics

(2009) Marco Simonetta et al.   PLOS BIOLOGY

The Human Spindle Assembly Checkpoint Protein Bub3 Is Required for the Establishment of Efficient Kinetochore–Microtubule Attachments

(2008) Elsa Logarinho et al.   MOLECULAR BIOLOGY OF THE CELL

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

(2008) Jakob Nilsson et al.   NATURE CELL BIOLOGY

Protein Metamorphosis: The Two-State Behavior of Mad2

(2008) Xuelian Luo et al.   STRUCTURE