TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors

TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation

(2015) Jan-Bernd Funcke et al.   FASEB JOURNAL

TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess

(2015) Leila Idrissova et al.   JOURNAL OF HEPATOLOGY

Regulated Cell Death: Signaling and Mechanisms

(2014) Avi Ashkenazi et al.   Annual Review of Cell and Developmental Biology

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Phase II Trial of Mapatumumab, a Fully Human Agonist Monoclonal Antibody to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor 1 (TRAIL-R1), in Combination With Paclitaxel and Carboplatin in Patients With Advanced Non–Small-Cell Lung Cancer

(2014) Joachim von Pawel et al.   Clinical Lung Cancer

Transcriptional Regulation of Adipocyte Differentiation: A Central Role for CCAAT/Enhancer-binding Protein (C/EBP) β

(2014) Liang Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor necrosis factor-related apoptosis-inducing ligand in vascular inflammation and atherosclerosis: A protector or culprit?

(2014) Wen Cheng et al.   VASCULAR PHARMACOLOGY

Adipose-derived mesenchymal stromal/stem cells: An update on their phenotype in vivo and in vitro

(2014) Patrick C Baer   World Journal of Stem Cells

Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family

(2013) K Azijli et al.   CELL DEATH AND DIFFERENTIATION

Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol

(2013) Gloria Brombo et al.   PLoS One

On the TRAIL of obesity and diabetes

(2013) Hanis H. Harith et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Low FasL levels promote proliferation of human bone marrow-derived mesenchymal stem cells, higher levels inhibit their differentiation into adipocytes

(2013) M R Rippo et al.   Cell Death & Disease

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma

(2013) M Keuper et al.   Cell Death & Disease

The energy balance positively regulates the levels of circulating TNF-related apoptosis inducing ligand in humans

(2012) Gianni Biolo et al.   CLINICAL NUTRITION

TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation

(2012) Stella Bernardi et al.   CLINICAL SCIENCE

Phase I Trial and Pharmacokinetic Study of Lexatumumab in Pediatric Patients With Solid Tumors

(2012) Melinda S. Merchant et al.   JOURNAL OF CLINICAL ONCOLOGY

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

(2012) Laura S. Dickens et al.   MOLECULAR CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe −/− mice

(2011) B. A. Di Bartolo et al.   DIABETOLOGIA

Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis

(2011) Pamela Fischer-Posovszky et al.   EXPERIMENTAL CELL RESEARCH

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

TRAIL Promotes VSMC Proliferation and Neointima Formation in a FGF-2–, Sp1 Phosphorylation–, and NFκB-Dependent Manner

(2010) Jeffrey Chan et al.   CIRCULATION RESEARCH

Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis

(2010) Isabelle Mader et al.   FASEB JOURNAL

LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism

(2010) G Tiller et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of TWEAK (TNF Superfamily Member 12) on Differentiation, Metabolism, and Secretory Function of Human Primary Preadipocytes and Adipocytes

(2009) Gabriele Tiller et al.   ENDOCRINOLOGY

Tumor Necrosis Factor-α Induces Caspase-mediated Cleavage of Peroxisome Proliferator-activated Receptor γ in Adipocytes

(2009) Adilson Guilherme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAIL Stimulates Proliferation of Vascular Smooth Muscle Cells via Activation of NF-κB and Induction of Insulin-like Growth Factor-1 Receptor

(2008) Mary M. Kavurma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-mediated Degradation of PPARγ Proteins in Adipocytes

(2008) Fang He et al.   Obesity

Human SGBS Cells – a Unique Tool for Studies of Human Fat Cell Biology

(2008) Pamela Fischer-Posovszky et al.   Obesity Facts