Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology

Deletion of Adenosine A2A Receptors From Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia

(2015) Marco Matos et al.   BIOLOGICAL PSYCHIATRY

Bioenergetic Mechanisms in Astrocytes May Contribute to Amyloid Plaque Deposition and Toxicity

(2015) Wen Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Oligodendrogenesis and Remyelination after Spinal Cord Injury in Mice and Rats

(2015) Z. C. Hesp et al.   JOURNAL OF NEUROSCIENCE

The function of aquaporin4 in ischemic brain edema

(2014) Wen-Wen Wang et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Schizophrenia: from dopaminergic to glutamatergic interventions

(2014) Marc Laruelle   CURRENT OPINION IN PHARMACOLOGY

Oligodendrocyte progenitors: Adult stem cells of the central nervous system?

(2014) A.H. Crawford et al.   EXPERIMENTAL NEUROLOGY

Myelination, oligodendrocytes, and serious mental illness

(2014) V. Haroutunian et al.   GLIA

Direct and Indirect Effects of Immune and Central Nervous System–Resident Cells on Human Oligodendrocyte Progenitor Cell Differentiation

(2014) Craig S. Moore et al.   JOURNAL OF IMMUNOLOGY

Desvenlafaxine prevents white matter injury and improves the decreased phosphorylation of the rate-limiting enzyme of cholesterol synthesis in a chronic mouse model of depression

(2014) Junhui Wang et al.   JOURNAL OF NEUROCHEMISTRY

Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis

(2014) Roy Y. Kim et al.   JOURNAL OF NEUROIMMUNOLOGY

Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation

(2014) Debayon Paul et al.   Journal of Neuroinflammation

Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model

(2014) Emily Mills Ko et al.   Journal of Neuroinflammation

Conditional Ablation of Astroglial CCL2 Suppresses CNS Accumulation of M1 Macrophages and Preserves Axons in Mice with MOG Peptide EAE

(2014) M. Moreno et al.   JOURNAL OF NEUROSCIENCE

Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination

(2014) C. G. Fulmer et al.   JOURNAL OF NEUROSCIENCE

Mutant disrupted-in-schizophrenia 1 in astrocytes: Focus on glutamate metabolism

(2014) Sofya Abazyan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Evidence for morphological alterations in prefrontal white matter glia in schizophrenia and bipolar disorder

(2014) Christa Hercher et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Can lactate serve as an energy substrate for axons in good times and in bad, in sickness and in health?

(2014) Selva Baltan   METABOLIC BRAIN DISEASE

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

(2014) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Astrocyte-Derived Proinflammatory Cytokines Induce Hypomyelination in the Periventricular White Matter in the Hypoxic Neonatal Brain

(2014) Yiyu Deng et al.   PLoS One

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Fibrillary astrocytes are decreased in the subgenual cingulate in schizophrenia

(2013) Matthew Williams et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Novel advances in the diagnosis and treatment of neuromyelitis optica: is there a need to redefine the gold standard?

(2013) Jérome de Seze et al.   Expert Review of Clinical Immunology

Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

(2013) Roman Fischer et al.   GLIA

Upregulation of glutamate transporter GLT-1 by mTOR-Akt-NF-кB cascade in astrocytic oxygen-glucose deprivation

(2013) Yi-Fei Ji et al.   GLIA

Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

(2013) Roberta Brambilla et al.   GLIA

Up-regulation of Ciliary Neurotrophic Factor in Astrocytes by Aspirin

(2013) Khushbu K. Modi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenotypic Conversions of "Protoplasmic" to "Reactive" Astrocytes in Alexander Disease

(2013) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

Dysregulated glutamate uptake by astrocytes causes oligodendroglia death in hypoxic perventricular white matter damage

(2013) Madhuvika Murugan et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Act1 mediates IL-17–induced EAE pathogenesis selectively in NG2+ glial cells

(2013) Zizhen Kang et al.   NATURE NEUROSCIENCE

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

(2013) Shin H Kang et al.   NATURE NEUROSCIENCE

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Multiple Roles for Astrocytes as Effectors of Cytokines and Inflammatory Mediators

(2013) Michael V. Sofroniew   NEUROSCIENTIST

The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

(2013) Diego Clemente et al.   Frontiers in Cellular Neuroscience

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

(2012) Wolfgang Brück et al.   ACTA NEUROPATHOLOGICA

Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels

(2012) Nicole Zimmermann et al.   BIOCHEMICAL JOURNAL

Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer’s disease

(2012) Magdalena Kulijewicz-Nawrot et al.   JOURNAL OF ANATOMY

Coming into View: Eukaryotic Iron Chaperones and Intracellular Iron Delivery: FIGURE 1.

(2012) Caroline C. Philpott   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

(2012) M. E. Hamby et al.   JOURNAL OF NEUROSCIENCE

Iron Efflux from Astrocytes Plays a Role in Remyelination

(2012) K. Schulz et al.   JOURNAL OF NEUROSCIENCE

Alexander Disease

(2012) A. Messing et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Requirement of Glycogenolysis for Uptake of Increased Extracellular K+ in Astrocytes: Potential Implications for K+ Homeostasis and Glycogen Usage in Brain

(2012) Junnan Xu et al.   NEUROCHEMICAL RESEARCH

Risk of vascular disease in patients with multiple sclerosis: a review

(2012) Christian Fynbo Christiansen   NEUROLOGICAL RESEARCH

Cognitive dysfunction and glutamate reuptake: Effect of EAAT2 polymorphism in schizophrenia

(2012) Marco Spangaro et al.   NEUROSCIENCE LETTERS

Myelination

(2012) Susan C. Barnett et al.   NEUROSCIENTIST

IFN-γ Signaling to Astrocytes Protects from Autoimmune Mediated Neurological Disability

(2012) Claudia Hindinger et al.   PLoS One

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

(2012) H.-H. Tsai et al.   SCIENCE

IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

(2011) Jenni Raasch et al.   BRAIN

Gp130-Dependent Astrocytic Survival Is Critical for the Control of Autoimmune Central Nervous System Inflammation

(2011) F. Haroon et al.   JOURNAL OF IMMUNOLOGY

Corticosteroids Impair Remyelination in the Corpus Callosum of Cuprizone-Treated Mice

(2011) T. Clarner et al.   JOURNAL OF NEUROENDOCRINOLOGY

Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate

(2011) J. E. Rinholm et al.   JOURNAL OF NEUROSCIENCE

Astrocytes from the Contused Spinal Cord Inhibit Oligodendrocyte Differentiation of Adult Oligodendrocyte Precursor Cells by Increasing the Expression of Bone Morphogenetic Proteins

(2011) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Bax and Calpain Mediate Excitotoxic Oligodendrocyte Death Induced by Activation of Both AMPA and Kainate Receptors

(2011) M. V. Sanchez-Gomez et al.   JOURNAL OF NEUROSCIENCE

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

(2011) Markel Olabarria et al.   Molecular Neurodegeneration

Riluzole elevates GLT-1 activity and levels in striatal astrocytes

(2011) Marica Carbone et al.   NEUROCHEMISTRY INTERNATIONAL

Structural Remodeling of Astrocytes in the Injured CNS

(2011) Daniel Sun et al.   NEUROSCIENTIST

ATP: A ubiquitous gliotransmitter integrating neuron–glial networks

(2011) Arthur M. Butt   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Astrocyte–neuron metabolic relationships: for better and for worse

(2011) Igor Allaman et al.   TRENDS IN NEUROSCIENCES

Inhibition of Na+/H+ Exchanger Isoform 1 Is Neuroprotective in Neonatal Hypoxic Ischemic Brain Injury

(2010) Pelin Cengiz et al.   ANTIOXIDANTS & REDOX SIGNALING

Searching for Neuropathology: Gliosis in Schizophrenia

(2010) Tatiana P. Schnieder et al.   BIOLOGICAL PSYCHIATRY

Demyelination versus remyelination in progressive multiple sclerosis

(2010) Stephan Bramow et al.   BRAIN

Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat

(2010) Takeshi Izawa et al.   BRAIN RESEARCH

TGFβ1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation

(2010) Yueting Zhang et al.   GLIA

Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor

(2010) M. Kernt et al.   GROWTH FACTORS

Anaerobic Function of CNS White Matter Declines with Age

(2010) Margaret A Hamner et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

How factors secreted from astrocytes impact myelin repair

(2010) Craig S. Moore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage

(2010) T. Ogata et al.   NEUROSCIENCE

Functions of astrocytes and their potential as therapeutic targets

(2010) Harold K. Kimelberg et al.   Neurotherapeutics

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse

(2009) Daniel Sun et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Transgenic Inhibition of Astroglial NF- B Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation

(2009) R. Brambilla et al.   JOURNAL OF IMMUNOLOGY

Cultured astrocytes derived from corpus callosum or cortical grey matter show distinct glutamate handling properties

(2009) Stéphanie Goursaud et al.   JOURNAL OF NEUROCHEMISTRY

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Uptake of ferrous iron by cultured rat astrocytes

(2009) Ketki Tulpule et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Binding and uptake of Aβ1-42 by primary human astrocytesin vitro

(2008) Henrietta M. Nielsen et al.   GLIA

Oligodendrocytes and myelination: The role of iron

(2008) Bozho Todorich et al.   GLIA

Quantification of astrocyte volume changes during ischemia in situ reveals two populations of astrocytes in the cortex of GFAP/EGFP mice

(2008) Jana Benesova et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Vascular Disease among Hospitalized Multiple Sclerosis Patients

(2008) Norrina B. Allen et al.   NEUROEPIDEMIOLOGY

Early iron deficiency produces persistent damage to visual tracts in Wistar rats

(2008) Aline S. DeMaman et al.   NUTRITIONAL NEUROSCIENCE

Aceruloplasminaemia with progressive atrophy without brain iron overload: treatment with oral chelation

(2007) F M Skidmore et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Regulation of pH in the mammalian central nervous system under normal and pathological conditions: Facts and hypotheses

(2007) Marta Obara et al.   NEUROCHEMISTRY INTERNATIONAL