Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods

Intermolecular Reaction Screening as a Tool for Reaction Evaluation

(2015) Karl D. Collins et al.   ACCOUNTS OF CHEMICAL RESEARCH

Where is the Oxygen? Structural Analysis of α-Humulene Oxidation Products by the Crystalline Sponge Method

(2015) Nicolas Zigon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The crystalline sponge method: MOF terminal ligand effects

(2015) Timothy R. Ramadhar et al.   CHEMICAL COMMUNICATIONS

Recent Applications of Phosphane-based Palladium Catalysts in Suzuki-Miyaura Reactions Involved in Total Syntheses of Natural Products

(2015) Renzo Rossi et al.   CURRENT ORGANIC CHEMISTRY

P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C–N, C–O, and C–C Cross-Coupling Reactions

(2015) Alexander Buitrago Santanilla et al.   ORGANIC LETTERS

A data-intensive approach to mechanistic elucidation applied to chiral anion catalysis

(2015) A. Milo et al.   SCIENCE

Analysis of rapidly synthesized guest-filled porous complexes with synchrotron radiation: practical guidelines for the crystalline sponge method

(2015) Timothy R. Ramadhar et al.   Acta Crystallographica A-Foundation and Advances

Rapid Assessment of Protecting-Group Stability by Using a Robustness Screen

(2014) Karl D. Collins et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iridium-Catalyzed C–H Borylation of Heteroarenes: Scope, Regioselectivity, Application to Late-Stage Functionalization, and Mechanism

(2014) Matthew A. Larsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Contemporary screening approaches to reaction discovery and development

(2014) Karl D. Collins et al.   Nature Chemistry

Application of a robustness screen for the evaluation of synthetic organic methodology

(2014) Karl D Collins et al.   Nature Protocols

Designer substrate library for quantitative, predictive modeling of reaction performance

(2014) E. N. Bess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

(2014) A. Buitrago Santanilla et al.   SCIENCE

Suzuki-Miyaura Cross-Coupling of Unprotected, Nitrogen-Rich Heterocycles: Substrate Scope and Mechanistic Investigation

(2013) M. Alexander Düfert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Throughput Optimization of Ir-Catalyzed C–H Borylation: A Tutorial for Practical Applications

(2013) Sean M. Preshlock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray analysis on the nanogram to microgram scale using porous complexes

(2013) Yasuhide Inokuma et al.   NATURE

A robustness screen for the rapid assessment of chemical reactions

(2013) Karl D. Collins et al.   Nature Chemistry

Employing a robustness screen: rapid assessment of rhodium(III)-catalysed C–H activation reactions

(2013) Karl D. Collins et al.   TETRAHEDRON

Copper-mediated cyanation of aryl boronic acids using benzyl cyanide

(2013) Yan Luo et al.   TETRAHEDRON

Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

(2012) Alan Nadin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Mediated Sequential Cyanation of Aryl C–B and Arene C–H Bonds Using Ammonium Iodide and DMF

(2012) Jinho Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CuI/DMPAO-Catalyzed N-Arylation of Acyclic Secondary Amines

(2012) Yu Zhang et al.   ORGANIC LETTERS

A C–H Borylation Approach to Suzuki–Miyaura Coupling of Typically Unstable 2–Heteroaryl and Polyfluorophenyl Boronates

(2012) Daniel W. Robbins et al.   ORGANIC LETTERS

The Complementary Competitors: Palladium and Copper in C–N Cross-Coupling Reactions

(2012) Irina P. Beletskaya et al.   ORGANOMETALLICS

Design and preparation of new palladium precatalysts for C–C and C–N cross-coupling reactions

(2012) Nicholas C. Bruno et al.   Chemical Science

Borylation and Silylation of C–H Bonds: A Platform for Diverse C–H Bond Functionalizations

(2011) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Copper(I)-Mediated Cyanation of Boronic Acids

(2011) Guoying Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Regioselectivity of the borylation of alkanes and arenes

(2011) John F. Hartwig   CHEMICAL SOCIETY REVIEWS

P450 Fingerprinting Method for Rapid Discovery of Terpene Hydroxylating P450 Catalysts with Diversified Regioselectivity

(2011) Kaidong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A General Rhodium-Catalyzed Cyanation of Aryl and Alkenyl Boronic Acids

(2010) Pazhamalai Anbarasan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyanation of Arenes via Iridium-Catalyzed Borylation

(2010) Carl W. Liskey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Palladium Precatalyst Allows for the Fast Suzuki−Miyaura Coupling Reactions of Unstable Polyfluorophenyl and 2-Heteroaryl Boronic Acids

(2010) Tom Kinzel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases

(2010) Debabrata Maiti et al.   Chemical Science

Room-Temperature Copper-Catalyzed Carbon-Nitrogen Coupling of Aryl Iodides and Bromides Promoted by Organic Ionic Bases

(2009) Chu-Ting Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

Visualization of the Chemical Space in Drug Discovery

(2008) Jose Medina-Franco et al.   Current Computer-Aided Drug Design

Efficient Cross-Coupling of Secondary Alkyltrifluoroborates with Aryl ChloridesReaction Discovery Using Parallel Microscale Experimentation

(2008) Spencer D. Dreher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Reactive, General and Long-Lived Catalysts for Palladium-Catalyzed Amination of Heteroaryl and Aryl Chlorides, Bromides, and Iodides: Scope and Structure–Activity Relationships

(2008) Qilong Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY