Role of Natural Radiosensitizers and Cancer Cell Radioresistance: An Update

Portrait of inflammatory response to ionizing radiation treatment

(2015) Federica Di Maggio et al.   Journal of Inflammation-London

MicroRNAs Used in Combination with Anti-Cancer Treatments Can Enhance Therapy Efficacy

(2015) Maddalena Mognato et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

(2014) Gopinath Sutendra et al.   CELL

Tug of War between Survival and Death: Exploring ATM Function in Cancer

(2014) Venturina Stagni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells

(2014) Pauline Rimmelé et al.   Stem Cell Reports

Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - Implication in modification of radiation damage

(2014) Anuranjani et al.   Redox Biology

Stem Cells, Redox Signaling, and Stem Cell Aging

(2013) Raymond Liang et al.   ANTIOXIDANTS & REDOX SIGNALING

Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo

(2013) J. M. Harris et al.   BLOOD

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

(2013) Ana P. Gomes et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

(2013) Keiyo Takubo et al.   Cell Stem Cell

Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation

(2013) Wen-Mei Yu et al.   Cell Stem Cell

Mechanisms of Radiation Toxicity in Transformed and Non-Transformed Cells

(2013) Ronald-Allan Panganiban et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aldolase sequesters WASP and affects WASP/Arp2/3-stimulated actin dynamics

(2013) Carolyn Ritterson Lew et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift

(2013) Silvia C. Formenti et al.   JNCI-Journal of the National Cancer Institute

The nexus of chromatin regulation and intermediary metabolism

(2013) Philipp Gut et al.   NATURE

MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines

(2013) S Grosso et al.   Cell Death & Disease

DNA Double-Strand Break Repair as Determinant of Cellular Radiosensitivity to Killing and Target in Radiation Therapy

(2013) Emil Mladenov et al.   Frontiers in Oncology

MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN

(2012) Changju Qu et al.   CELL CYCLE

Radiation-inducible Immunotherapy for Cancer: Senescent Tumor Cells as a Cancer Vaccine

(2012) Yuru Meng et al.   MOLECULAR THERAPY

MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

(2012) Marek Svoboda et al.   Radiation Oncology

Cancer Stem Cells: Targets and Potential Biomarkers for Radiotherapy

(2011) M. Krause et al.   CLINICAL CANCER RESEARCH

The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation

(2011) Jennifer R. Hom et al.   DEVELOPMENTAL CELL

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

(2011) Jin Zhang et al.   EMBO JOURNAL

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

p38 MAPK-Mediated Bmi-1 Down-Regulation and Defective Proliferation in ATM-Deficient Neural Stem Cells Can Be Restored by Akt Activation

(2011) Jeesun Kim et al.   PLoS One

Radiation-Induced Bystander Effects: What Are They, and How Relevant Are They to Human Radiation Exposures?

(2011) Benjamin J. Blyth et al.   RADIATION RESEARCH

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Senescent cells as a source of inflammatory factors for tumor progression

(2010) Albert R. Davalos et al.   CANCER AND METASTASIS REVIEWS

Blockade of Tumor Necrosis Factor   Signaling in Tumor-Associated Macrophages as a Radiosensitizing Strategy

(2010) Y. Meng et al.   CANCER RESEARCH

Immune Promotion of Epithelial-mesenchymal Transition and Generation of Breast Cancer Stem Cells

(2010) J. M. Reiman et al.   CANCER RESEARCH

New Insights into Checkpoint Kinase 1 in the DNA Damage Response Signaling Network

(2010) Y. Dai et al.   CLINICAL CANCER RESEARCH

Reactive oxygen species: A radical role in development?

(2010) David Hernández-García et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting DNA-PKcs and ATM with miR-101 Sensitizes Tumors to Radiation

(2010) Dan Yan et al.   PLoS One

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

DNA-damage response, survival and differentiation in vitro of a human neural stem cell line in relation to ATM expression

(2009) L Carlessi et al.   CELL DEATH AND DIFFERENTIATION

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity

(2009) Tobias B Dansen et al.   Nature Chemical Biology

Loss of ATM Impairs Proliferation of Neural Stem Cells Through Oxidative Stress-Mediated p38 MAPK Signaling

(2009) Jeesun Kim et al.   STEM CELLS

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL