Editor’s Highlight: Modeling Compound-Induced FibrogenesisIn VitroUsing Three-Dimensional Bioprinted Human Liver Tissues

Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro

(2016) Sofia B. Leite et al.   BIOMATERIALS

Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis

(2016) Inge M. Westra et al.   TOXICOLOGY IN VITRO

Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro

(2016) Deborah G. Nguyen et al.   PLoS One

Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies

(2014) C.M. Maybury et al.   BRITISH JOURNAL OF DERMATOLOGY

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

Identification of Hepatic Phospholipidosis Inducers in Sandwich-Cultured Rat Hepatocytes, a Physiologically Relevant Model, Reveals Altered Basolateral Uptake and Biliary Excretion of Anionic Probe Substrates

(2014) Brian C. Ferslew et al.   TOXICOLOGICAL SCIENCES

Hepatic inflammation and progressive liver fibrosis in chronic liver disease

(2014) Albert J Czaja   WORLD JOURNAL OF GASTROENTEROLOGY

Animal models of chronic liver diseases

(2012) Yan Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Metabolism and Toxicity of Thioacetamide and Thioacetamide S-Oxide in Rat Hepatocytes

(2012) Heather Hajovsky et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Organotypic liver culture models: Meeting current challenges in toxicity testing

(2012) Edward L. LeCluyse et al.   CRITICAL REVIEWS IN TOXICOLOGY

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models for the study of hepatic fibrosis

(2011) Peter Starkel et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

(2011) Christer Baeck et al.   GUT

IL-6 induces hepatic inflammation and collagen synthesis in vivo

(2010) I. CHOI et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Assessment and management of methotrexate hepatotoxicity in psoriasis patients: report from a consensus conference to evaluate current practice and identify key questions toward optimizing methotrexate use in the clinic

(2010) J. Barker et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Interleukin-1 participates in the progression from liver injury to fibrosis

(2009) Roben G. Gieling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy

(2009) K. Lindsay et al.   RHEUMATOLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Tissue Engineering by Self-Assembly of Cells Printed into Topologically Defined Structures

(2008) Karoly Jakab et al.   TISSUE ENGINEERING PART A