Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro

Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a HumanIn VitroLiver Model: An Approach to Study DILI

(2015) Victoria Kegel et al.   MEDIATORS OF INFLAMMATION

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

Induction of Influx and Efflux Transporters and Cytochrome P450 3A4 in Primary Human Hepatocytes by Rifampin, Rifabutin, and Rifapentine

(2013) Beth Williamson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

(2013) Radina Kostadinova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Multi-cell type human liver microtissues for hepatotoxicity testing

(2012) S. Messner et al.   ARCHIVES OF TOXICOLOGY

In vitro models for liver toxicity testing

(2012) Valerie Y. Soldatow et al.   Toxicology Research

Hepatic stellate cells require a stiff environment for myofibroblastic differentiation

(2011) Abby L. Olsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing

(2011) Rui M. Tostões et al.   HEPATOLOGY

Layered patterning of hepatocytes in co-culture systems using microfabricated stencils

(2010) Cheul Cho et al.   BIOTECHNIQUES

Idiosyncratic Drug-Induced Liver Injury and the Role of Inflammatory Stress with an Emphasis on an Animal Model of Trovafloxacin Hepatotoxicity

(2010) Patrick J. Shaw et al.   TOXICOLOGICAL SCIENCES

Review article: diagnosis and treatment of non-alcoholic fatty liver disease

(2008) M. K. OH et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Tissue Engineering by Self-Assembly of Cells Printed into Topologically Defined Structures

(2008) Karoly Jakab et al.   TISSUE ENGINEERING PART A