Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer

Critical role of MKP-1 in lipopolysaccharide-induced osteoclast formation through CXCL1 and CXCL2

(2015) Michael S. Valerio et al.   CYTOKINE

Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms

(2015) Mackenzie Herroon et al.   Oncotarget

Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases

(2014) Aimalie L. Hardaway et al.   CANCER AND METASTASIS REVIEWS

Blockade of visfatin induction by oleanolic acid via disturbing IL-6-TRAF6-NF-κB signaling of adipocytes

(2014) Hyun-Sung Kim et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Managing bone metastases and reducing skeletal related events in prostate cancer

(2014) Benjamin A. Gartrell et al.   Nature Reviews Clinical Oncology

Corticotrophin-Releasing Factor (CRF) and the Urocortins Are Potent Regulators of the Inflammatory Phenotype of Human and Mouse White Adipocytes and the Differentiation of Mouse 3T3L1 Pre-Adipocytes

(2014) Eirini Dermitzaki et al.   PLoS One

Autocrine signaling is a key regulatory element during osteoclastogenesis

(2014) P. Kopesky et al.   Biology Open

Biologic therapies and systemic bone loss in rheumatoid arthritis

(2013) Theodoros Dimitroulas et al.   AUTOIMMUNITY REVIEWS

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Determinants of bone marrow adiposity: The modulation of peroxisome proliferator-activated receptor-γ2 activity as a central mechanism

(2013) H. Sadie-Van Gijsen et al.   BONE

New insights into osteoporosis: the bone-fat connection

(2013) M. Kawai et al.   JOURNAL OF INTERNAL MEDICINE

CXCL5 stimulation of RANK ligand expression in Paget’s disease of bone

(2013) Kumaran Sundaram et al.   LABORATORY INVESTIGATION

Nutritionally Mediated Oxidative Stress and Inflammation

(2013) Alexandra Muñoz et al.   Oxidative Medicine and Cellular Longevity

Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist

(2013) Brian R Leaker et al.   RESPIRATORY RESEARCH

Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?

(2013) L. M. Coussens et al.   SCIENCE

CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction

(2012) Erika Oue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genes associate with abnormal bone cell activity in bone metastasis

(2012) G. David Roodman   CANCER AND METASTASIS REVIEWS

Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2

(2012) Peter H. Killian et al.   CARCINOGENESIS

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial

(2012) P. Nair et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Marrow Fat and the Bone Microenvironment: Developmental, Functional, and Pathological Implications

(2012) Clifford J. Rosen et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Progesterone and calcitriol attenuate inflammatory cytokines CXCL1 and CXCL2 in ovarian and endometrial cancer cells

(2012) Leyla Kavandi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The role of CXC chemokines and their receptors in the progression and treatment of tumors

(2012) Qingchao Zhu et al.   JOURNAL OF MOLECULAR HISTOLOGY

Macrophage cathepsin K promotes prostate tumor progression in bone

(2012) M K Herroon et al.   ONCOGENE

Lipids and prostate cancer

(2012) Janel Suburu et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes

(2011) A. Krings et al.   BONE

Marrow fat metabolism is linked to the systemic energy metabolism

(2011) Beata Lecka-Czernik   BONE

 2-Microglobulin Induces Epithelial to Mesenchymal Transition and Confers Cancer Lethality and Bone Metastasis in Human Cancer Cells

(2011) S. Josson et al.   CANCER RESEARCH

High-fat diet activates pro-inflammatory response in the prostate through association of Stat-3 and NF-κB

(2011) Eswar Shankar et al.   PROSTATE

Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice

(2010) Jay J. Cao et al.   Annals of the New York Academy of Sciences

Treatment and prevention of bone complications from prostate cancer

(2010) Richard J. Lee et al.   BONE

Skeletal aging and the adipocyte program

(2010) Beata Lecka-Czernik et al.   CELL CYCLE

Interleukin-6 in bone metastasis and cancer progression

(2010) Tasnim Ara et al.   EUROPEAN JOURNAL OF CANCER

Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice

(2010) Ganesh V. Halade et al.   EXPERIMENTAL GERONTOLOGY

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXC Chemokine Ligand 2 Induced by Receptor Activator of NF- B Ligand Enhances Osteoclastogenesis

(2010) J. Ha et al.   JOURNAL OF IMMUNOLOGY

Saturated fatty acids enhance osteoclast survival

(2010) S. R. Oh et al.   JOURNAL OF LIPID RESEARCH

High fat diet-induced animal model of age-associated obesity and osteoporosis

(2010) Ganesh V. Halade et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

PPARs in Bone: The Role in Bone Cell Differentiation and Regulation of Energy Metabolism

(2010) Beata Lecka-Czernik   Current Osteoporosis Reports

Bone Marrow-Derived Cathepsin K Cleaves SPARC in Bone Metastasis

(2009) Izabela Podgorski et al.   AMERICAN JOURNAL OF PATHOLOGY

Cathepsin K: A therapeutic target for bone diseases

(2009) Qingxiao Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice

(2009) Jay J. Cao et al.   BONE

Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer

(2009) M D Brown et al.   BRITISH JOURNAL OF CANCER

CXC Ligand 5 Is an Adipose-Tissue Derived Factor that Links Obesity to Insulin Resistance

(2009) Carine Chavey et al.   Cell Metabolism

The Chemokine Cxcl1 Is a Novel Target Gene of Parathyroid Hormone (PTH)/PTH-Related Protein in Committed Osteoblasts

(2009) Döne Onan et al.   ENDOCRINOLOGY

The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies

(2009) J. Hol et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Osteoclastogenesis by Bone Marrow-Derived Macrophages Is Enhanced in Obese Mice

(2009) Tae-Wook Kyung et al.   JOURNAL OF NUTRITION

Molecular mechanisms of metastasis in prostate cancer

(2008) Noel W. Clarke et al.   ASIAN JOURNAL OF ANDROLOGY

Receptor activator of NF-κB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells

(2008) Valerie A Odero-Marah et al.   CELL RESEARCH

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

DNA microarray analyses of genes expressed differentially in 3T3-L1 adipocytes co-cultured with murine macrophage cell line RAW264.7 in the presence of the toll-like receptor 4 ligand bacterial endotoxin

(2008) A Yamashita et al.   INTERNATIONAL JOURNAL OF OBESITY

Osteoclasts Are Active in Bone Forming Metastases of Prostate Cancer Patients

(2008) Ilaria Roato et al.   PLoS One