Efficient Generation of β-Globin-Expressing Erythroid Cells Using Stromal Cell-Derived Induced Pluripotent Stem Cells from Patients with Sickle Cell Disease

Pluripotent stem cell based gene therapy for hematological diseases

(2016) Stijn Vanhee et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

β-Globin-Expressing Definitive Erythroid Progenitor Cells Generated from Embryonic and Induced Pluripotent Stem Cell-Derived Sacs

(2016) Atsushi Fujita et al.   STEM CELLS

De novo generation of HSCs from somatic and pluripotent stem cell sources

(2015) L. T. Vo et al.   BLOOD

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

(2015) Andrea Ditadi et al.   NATURE CELL BIOLOGY

Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation

(2015) Xiaosong Huang et al.   STEM CELLS

Inducing definitive hematopoiesis in a dish

(2014) Mervin C Yoder   NATURE BIOTECHNOLOGY

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

(2014) Christopher M Sturgeon et al.   NATURE BIOTECHNOLOGY

Multicolor Staining of Globin Subtypes Reveals Impaired Globin Switching During Erythropoiesis in Human Pluripotent Stem Cells

(2014) Kiyosumi Ochi et al.   Stem Cells Translational Medicine

Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34+ cells

(2013) R. K. Merling et al.   BLOOD

Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs

(2013) Thomas Winkler et al.   JOURNAL OF CLINICAL INVESTIGATION

Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells

(2013) Ryo Kurita et al.   PLoS One

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34+ Cells Correlates With In Vivo Vector Copy Number

(2013) Naoya Uchida et al.   Molecular Therapy-Nucleic Acids

Identification of the Hemogenic Endothelial Progenitor and Its Direct Precursor in Human Pluripotent Stem Cell Differentiation Cultures

(2012) Kyung-Dal Choi et al.   Cell Reports

Novel, High-Yield Red Blood Cell Production Methods from CD34-Positive Cells Derived from Human Embryonic Stem, Yolk Sac, Fetal Liver, Cord Blood, and Peripheral Blood

(2012) Emmanuel Olivier et al.   Stem Cells Translational Medicine

Large-scale in-vitro expansion of RBCs from hematopoietic stem cells

(2012) Balasundari Ramesh et al.   Artificial Cells Nanomedicine and Biotechnology

Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease

(2011) J. Zou et al.   BLOOD

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

(2011) Bin-Kuan Chou et al.   CELL RESEARCH

Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region

(2011) Andrejs Ivanovs et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of Red Blood Cells from Human Induced Pluripotent Stem Cells

(2011) Jessica Dias et al.   STEM CELLS AND DEVELOPMENT

A zinc-finger transcriptional activator designed to interact with the  -globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts

(2010) A. Wilber et al.   BLOOD

Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine

(2010) H. Lapillonne et al.   HAEMATOLOGICA

Epigenetic memory in induced pluripotent stem cells

(2010) K. Kim et al.   NATURE

Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence

(2010) Qiang Feng et al.   STEM CELLS

Development of a Human Immunodeficiency Virus Type 1-Based Lentiviral Vector That Allows Efficient Transduction of both Human and Rhesus Blood Cells

(2009) N. Uchida et al.   JOURNAL OF VIROLOGY

Leukemogenesis of b2a2-type p210 BCR/ABL in a Bone Marrow Transplantation Mouse Model Using a Lentiviral Vector

(2009) Naoya Uchida et al.   JOURNAL OF NIPPON MEDICAL SCHOOL

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

(2008) N. Takayama et al.   BLOOD

Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells

(2008) E. T. Zambidis et al.   BLOOD

Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis

(2008) F. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA