Expanded Hematopoietic Progenitor Cells Reselected for High Aldehyde Dehydrogenase Activity Demonstrate Islet Regenerative Functions

Rationale and Design for PACE: Patients with Intermittent Claudication Injected with ALDH Bright Cells

(2014) Emerson C. Perin et al.   AMERICAN HEART JOURNAL

Aldehyde dehydrogenase 1 activity in the developing human pancreas modulates retinoic acid signalling in mediating islet differentiation and survival

(2013) Jinming Li et al.   DIABETOLOGIA

Concise Review: Ex Vivo Expansion of Cord Blood-Derived Hematopoietic Stem and Progenitor Cells: Basic Principles, Experimental Approaches, and Impact in Regenerative Medicine

(2013) Patricia Flores-Guzmán et al.   Stem Cells Translational Medicine

Randomized, double-blind pilot study of transendocardial injection of autologous aldehyde dehydrogenase–bright stem cells in patients with ischemic heart failure

(2012) Emerson C. Perin et al.   AMERICAN HEART JOURNAL

Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells

(2012) Yong Zhao et al.   BMC Medicine

Linking Diabetes With Oxidative Stress, Adipokines, and Impaired Endothelial Precursor Cell Function

(2012) David A. Hess et al.   CANADIAN JOURNAL OF CARDIOLOGY

Rapid Expansion of Human Hematopoietic Stem Cells by Automated Control of Inhibitory Feedback Signaling

(2012) Elizabeth Csaszar et al.   Cell Stem Cell

Hematopoiesis: A Human Perspective

(2012) Sergei Doulatov et al.   Cell Stem Cell

Infusion of Mesenchymal Stem Cells Ameliorates Hyperglycemia in Type 2 Diabetic Rats: Identification of a Novel Role in Improving Insulin Sensitivity

(2012) Y. Si et al.   DIABETES

Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

(2012) R. Parsa et al.   DIABETES

Intrapancreatic delivery of human umbilical cord blood aldehyde dehydrogenase-producing cells promotes islet regeneration

(2012) G. I. Bell et al.   DIABETOLOGIA

Semaphorin 4A Exerts a Proangiogenic Effect by Enhancing Vascular Endothelial Growth Factor-A Expression in Macrophages

(2012) C. Meda et al.   JOURNAL OF IMMUNOLOGY

Umbilical Cord Blood-Derived Aldehyde Dehydrogenase-Expressing Progenitor Cells Promote Recovery from Acute Ischemic Injury

(2012) David M. Putman et al.   STEM CELLS

Combinatorial Human Progenitor Cell Transplantation Optimizes Islet Regeneration Through Secretion of Paracrine Factors

(2012) Gillian I. Bell et al.   STEM CELLS AND DEVELOPMENT

Concise Review: Pancreas Regeneration: Recent Advances and Perspectives

(2012) Philippe A. Lysy et al.   Stem Cells Translational Medicine

Ex vivo expansion of human hematopoietic stem and progenitor cells

(2011) A. Dahlberg et al.   BLOOD

Relation between the frequency of CD34+ bone marrow derived circulating progenitor cells and the number of diseased coronary arteries in patients with myocardial ischemia and diabetes

(2011) Ilkay Bozdag-Turan et al.   Cardiovascular Diabetology

A randomized, controlled study of autologous therapy with bone marrow-derived aldehyde dehydrogenase bright cells in patients with critical limb ischemia

(2011) Emerson C. Perin et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Concise Review: Aldehyde Dehydrogenase Bright Stem and Progenitor Cell Populations from Normal Tissues: Characteristics, Activities, and Emerging Uses in Regenerative Medicine

(2011) Andrew E. Balber   STEM CELLS

Transplanted Human Bone Marrow Progenitor Subtypes Stimulate Endogenous Islet Regeneration and Revascularization

(2011) Gillian I. Bell et al.   STEM CELLS AND DEVELOPMENT

Independence of exogenous insulin following immunoablation and stem cell reconstitution in newly diagnosed diabetes type I

(2010) E Snarski et al.   BONE MARROW TRANSPLANTATION

Bone Marrow and Pancreatic Islets: An Old Story with New Perspectives

(2010) Fabio Ciceri et al.   CELL TRANSPLANTATION

Islet Versus Pancreas Transplantation in Type 1 Diabetes: Competitive or Complementary?

(2010) Barbara Ludwig et al.   Current Diabetes Reports

Decreased Circulating Progenitor Cell Number and Failed Mechanisms of Stromal Cell-Derived Factor-1α Mediated Bone Marrow Mobilization Impair Diabetic Tissue Repair

(2010) Oren M. Tepper et al.   DIABETES

Residual Insulin Production and Pancreatic  -Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study

(2010) H. A. Keenan et al.   DIABETES

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

(2010) Colleen Delaney et al.   NATURE MEDICINE

Stem cell therapy for type 1 diabetes mellitus

(2010) Cristina Aguayo-Mazzucato et al.   Nature Reviews Endocrinology

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

(2010) Anthony E. Boitano et al.   SCIENCE

Hypoxia Responsive Mesenchymal Stem Cells Derived from Human Umbilical Cord Blood Are Effective for Bone Repair

(2010) Masumi Nagano et al.   STEM CELLS AND DEVELOPMENT

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

(2009) B. J. Capoccia et al.   BLOOD

Autologous Umbilical Cord Blood Transfusion in Very Young Children With Type 1 Diabetes

(2009) M. J. Haller et al.   DIABETES CARE

Aldehyde Dehydrogenase Activity Identifies a Population of Human Skeletal Muscle Cells With High Myogenic Capacities

(2009) Karine Vauchez et al.   MOLECULAR THERAPY

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

(2009) M. Rovira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy

(2008) Stefania Corti et al.   JOURNAL OF CLINICAL INVESTIGATION

Widespread Nonhematopoietic Tissue Distribution by Transplanted Human Progenitor Cells with High Aldehyde Dehydrogenase Activity

(2007) David A. Hess et al.   STEM CELLS

Mesenchymal Stem Cells Cooperate with Bone Marrow Cells in Therapy of Diabetes

(2007) Veronika S. Urbán et al.   STEM CELLS