Article
Medicine, General & Internal
Qingqing Xiao, Bin Cai, Anwen Yin, Huanhuan Huo, Keke Lan, Guo Zhou, Linghong Shen, Ben He
Summary: Nonlinear associations between serum 25(OH)D levels and all-cause and cardiovascular disease (CVD) mortality were observed in American patients with osteoarthritis (OA). The thresholds of 27.70 and 54.40 nmol/L for CVD and all-cause mortality, respectively, may represent intervention targets for lowering the risk of premature death and cardiovascular disease.
Article
Nutrition & Dietetics
Huan Yu, Junhui Wu, Hongbo Chen, Mengying Wang, Siyue Wang, Ruotong Yang, Siyan Zhan, Xueying Qin, Tao Wu, Yiqun Wu, Yonghua Hu
Summary: This retrospective population-based cohort study found a significant association between adherent usage of glucosamine and increased risk of cardiovascular diseases in patients with osteoarthritis.
Article
Cardiac & Cardiovascular Systems
Bin Zhang, Zhi-Fei Li, Zhuo-Yu An, Li Zhang, Jing-Yi Wang, Meng-Di Hao, Yi-Jing Jin, Dong Li, An-Jian Song, Qiang Ren, Wen-Biao Chen
Summary: The study found that asthma patients have an increased risk of cardiovascular disease morbidity and mortality, as well as all-cause mortality. Female asthma patients have a higher risk of cardiovascular disease morbidity and all-cause mortality, and late-onset asthma patients have a higher risk of cardiovascular disease morbidity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Clinical Neurology
Xinyu Peng, Yang Lu, Pang-Yen Chen, Chiong-Hee Wong
Summary: This study based on the NHANES database explored the association between OA and CVD-related mortality, and found that depression played a slight mediating role in this relationship. These results serve as a reminder to pay attention to and effectively manage mental health to prevent CVD-related mortality.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Drazen Bedekovic, Damir Kirner, Ivica Bosnjak, Aleksandar Kibel, Sandra Saric, Srdan Novak, Visnja Prus
Summary: Rheumatoid arthritis (RA) increases the risk of cardiovascular diseases (CVDs), mainly due to arterial hypertension (HT). However, this study found no difference in HT prevalence between RA and osteoarthritis (OA) groups, but the RA group had a higher incidence of CVDs. RA patients with long-term remission had a slightly lower HT prevalence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jiang-lin Wang, Wen-jun Yin, Ling-yun Zhou, Ya-feng Wang, Xiao-cong Zuo
Summary: Smoking status, intensity, duration of smoking cessation, and age of smoking initiation all have significant impacts on the risk of all-cause and cause-specific mortality among cardiovascular disease patients, with smokers having higher risks of mortality but a significant decrease after quitting smoking.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Geriatrics & Gerontology
Nicola Veronese, Germain Honvo, Olivier Bruyere, Rene Rizzoli, Mario Barbagallo, Stefania Maggi, Lee Smith, Shaun Sabico, Nasser Al-Daghri, Cyrus Cooper, Francesco Pegreffi, Jean-Yves Reginster
Summary: This umbrella review examined the association between knee osteoarthritis and adverse health outcomes. The results showed that knee osteoarthritis is significantly associated with cardiovascular mortality, falls, and conditions related to subclinical atherosclerosis. However, the certainty of this evidence is weak.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Sadiya S. Khan, Hongyan Ning, Arjun Sinha, John Wilkins, Norrina B. Allen, Thanh Huyen T. Vu, Jarett D. Berry, Donald M. Lloyd-Jones, Ranya Sweis
Summary: This study found that smoking is significantly associated with premature death, whether related to cardiovascular disease or not. Smoking not only increases the risk of cardiovascular disease, but also leads to an earlier onset of cardiovascular disease.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Multidisciplinary Sciences
Gudrun Hoskuldsdottir, Stefan Franzen, Katarina Eeg-Olofsson, Bjorn Eliasson
Summary: This study aimed to explore the development risk of comorbidities in type 2 diabetes patients and evaluate the impact of common risk factors. The study found that all comorbidities gradually increased over time, with women having a lower risk compared to men.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Jonas Tagt, Emilie Helte, Carolina Donat-Vargas, Susanna C. Larsson, Karl Michaelsson, Alicja Wolk, Marie Vahter, Maria Kippler, Agneta Akesson
Summary: This study assessed the association of urinary cadmium (U-Cd) with fractures, myocardial infarction, heart failure, ischemic stroke, and mortality in postmenopausal women. The results indicated that long-term cadmium exposure might be associated with increased risk of fractures and all-cause mortality at lower levels than previously suggested.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Orthopedics
L. Kuusalo, D. T. Felson, N. Wang, C. E. Lewis, J. Torner, M. C. Nevitt, T. Neogi
Summary: This study found that there was no significant association between diabetes and cardiovascular disease with prevalent or incident knee osteoarthritis.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Article
Cardiac & Cardiovascular Systems
Patricio Lopez-Jaramillo, Philip Joseph, Jose P. Lopez-Lopez, Fernando Lanas, Alvaro Avezum, Rafael Diaz, Paul A. Camacho, Pamela Seron, Gustavo Oliveira, Andres Orlandini, Sumathy Rangarajan, Shofiqul Islam, Salim Yusuf
Summary: In a multinational South American cohort, variations in CVD incidence and mortality rates were examined between sub-populations stratified by country, sex, and urban or rural location. The study found that men had higher rates of CVD and death compared to women, and death rates were higher in rural areas. Hypertension, obesity, diabetes, and tobacco use were identified as leading risk factors for both CVD and death.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Chao Zeng, Lynn Rosenberg, Xiaoxiao Li, Luc Djousse, Jie Wei, Guanghua Lei, Yuqing Zhang
Summary: This study found that the initiation of sodium-containing acetaminophen is associated with increased risks of cardiovascular disease and all-cause mortality among both individuals with and without hypertension. It suggests that individuals should avoid unnecessary excessive sodium intake through sodium-containing acetaminophen use.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Jawad H. Butt, Emil L. Fosbol, Thomas A. Gerds, Charlotte Andersson, Kristian Kragholm, Tor Biering-Sorensen, Julie Andersen, Mathew Phelps, Mikkel Porsborg Andersen, Gunnar Gislason, Christian Torp-Pedersen, Lars Kober, Morten Schou
Summary: A study investigated mortality rates in patients with established cardiovascular disease in Denmark during the nationwide lockdown in 2020. It found that before the lockdown, mortality rates were significantly lower in 2020 compared to 2019, and during and after the lockdown the overall mortality rate was not significantly different. However, in-hospital mortality rate was lower and out-of-hospital mortality rate was higher during and after lockdown compared to the same period in 2019.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Peter Kokkinos, Charles Faselis, Immanuel Babu Henry Samuel, Carl J. Lavie, Jiajia Zhang, Jose D. Vargas, Andreas Pittaras, Michael Doumas, Pamela Karasik, Hans Moore, Michael Heimal, Jonathan Myers
Summary: This study evaluated the association between cardiorespiratory fitness and mortality risk and found that changes in cardiorespiratory fitness were inversely proportional to mortality risk. The results suggest that even small changes in cardiorespiratory fitness have a significant impact on mortality risk.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Lee Smith, Damiano Pizzol, Guillermo F. Lopez-Sanchez, Hans Oh, Louis Jacob, Lin Yang, Nicola Veronese, Pinar Soysal, Daragh McDermott, Yvonne Barnett, Laurie Butler, Ai Koyanagi
Summary: This study investigated the association between body weight and anxiety symptoms in older adults from low and middle income countries. The results showed that underweight and class III obesity were significantly associated with anxiety symptoms, with class III obesity only affecting males. Further research is needed to understand the reason behind this association.
WIENER KLINISCHE WOCHENSCHRIFT
(2023)
Article
Medicine, General & Internal
Katerina Nikolitch, Gayatri Saraf, Marco Solmi, Kurt Kroenke, Jess G. Fiedorowicz
MEDICAL CLINICS OF NORTH AMERICA
(2023)
Review
Biochemistry & Molecular Biology
Marco Solmi, Giovanni Croatto, Giada Piva, Stella Rosson, Paolo Fusar-Poli, Jose M. Rubio, Andre F. Carvalho, Eduard Vieta, Celso Arango, Nicole R. DeTore, Elizabeth S. Eberlin, Kim T. Mueser, Christoph U. Correll
Summary: Psychosocial interventions play an important role in schizophrenia and early psychosis. However, the literature on this topic is heterogeneous and contradictory. This umbrella review summarizes the findings from multiple meta-analyses comparing the effectiveness of different psychosocial interventions with standard treatment or other active interventions. The results suggest that early intervention services and cognitive behavioral therapy have significant effects on symptom reduction and functional improvement in early psychosis. For schizophrenia patients, cognitive behavioral therapy, psychoeducation, and any family interventions show positive effects on symptom reduction, relapse prevention, and functional improvement.
MOLECULAR PSYCHIATRY
(2023)
Article
Geriatrics & Gerontology
Lee Smith, Guillermo F. Lopez Sanchez, Nicola Veronese, Pinar Soysal, Karel Kostev, Louis Jacob, Masoud Rahmati, Agnieszka Kujawska, Mark A. Tully, Laurie Butler, Jae Il Shin, Ai Koyanagi
Summary: This study investigated the association between pain and sarcopenia in older adults from 6 low- and middle-income countries, and identified potential mediators. The results showed that higher levels of pain were associated with an increased risk of sarcopenia. Disability, sedentary behavior, and low mobility were identified as potential mediators.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Endocrinology & Metabolism
Amanda Casirati, Silvia Crotti, Alessandro Raffaele, Riccardo Caccialanza, Emanuele Cereda
Summary: Diseases of the liver and the digestive system can lead to malnutrition and changes in body composition. Phase angle (PhA) is a useful indicator for assessing nutritional status and body composition in patients with inflammatory bowel and liver diseases.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2023)
Article
Geriatrics & Gerontology
Lee Smith, Guillermo F. Lopez Sanchez, Nicola Veronese, Pinar Soysal, Masoud Rahmati, Louis Jacob, Karel Kostev, Josep Maria Haro, Abdullah Ahmed Alghamdi, Laurie Butler, Yvonne Barnett, Helen Keyes, Mark A. Tully, Jae Shin, Ai Koyanagi
Summary: This study examined the longitudinal relationship between dynapenic abdominal obesity (DAO) and future fall risk in middle-aged and older individuals from Ireland. The results showed that individuals with DAO at baseline had a higher likelihood of falls occurring during the 2-year follow-up period. Interventions to prevent or reverse DAO may be beneficial for reducing fall risk.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Lee Smith, Guillermo F. Lopez Sanchez, Damiano Pizzol, Masoud Rahmati, Dong Keon Yon, Andrew Morrison, Jasmine Samvelyan, Nicola Veronese, Pinar Soysal, Mark A. Tully, Laurie Butler, Yvonne Barnett, Jae Il Shin, Ai Koyanagi
Summary: This study aimed to examine the association between unclean cooking fuel use and gait speed in older adults, and found that using unclean cooking fuel was significantly associated with slower gait speed.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Public, Environmental & Occupational Health
Garcia Ashdown-Franks, Catherine M. Sabiston, Brendon Stubbs, Michael Atkinson, Helen Quirk, Alice Bullas, Steve Haake
Summary: Engagement in recreational activities has positive impacts on the physical and mental health of individuals with mental health conditions. The study explores the impact of recreational-based volunteering, specifically parkrun, on the health, social, and wellbeing of individuals with mental health conditions. Results show that participating in both running/walking and volunteering at parkrun leads to a stronger sense of community and facilitates meeting new people compared to solely participating in running/walking. These findings highlight the importance of the volunteer aspect in recreational activities for individuals' recovery and well-being.
PSYCHOLOGY HEALTH & MEDICINE
(2023)
Letter
Psychiatry
Valerie Brandt, Yuning Zhang, Hannah Carr, Dennis Golm, Christoph U. Correll, Gonzalo Arrondo, Joseph Firth, Lamiece Hassan, Marco Solmi, Samuele Cortese
Review
Geriatrics & Gerontology
Konstantinos Prokopidis, Panagiotis Giannos, Jean Yves Reginster, Olivier Bruyere, Mirko Petrovic, Antonio Cherubini, Konstantinos K. Triantafyllidis, Konstantinos S. Kechagias, Yannis Dionyssiotis, Matteo Cesari, Kinda Ibrahim, David Scott, Mario Barbagallo, Nicola Veronese
Summary: Polypharmacy in older adults is associated with negative consequences on muscular function, regardless of medical conditions. This systematic review and meta-analysis found that sarcopenia is significantly associated with a higher prevalence of polypharmacy and increased number of medications. The analysis included 29 studies and showed that individuals with sarcopenia had a higher risk of polypharmacy and used more medications compared to those without sarcopenia. However, variations were observed due to different populations. Future research should investigate the direct contribution of specific medications and the number of medications to the progression of sarcopenia in older adults.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Review
Oncology
Anastasios Gkountakos, Filippo M. M. Martelli, Nicola Silvestris, Michele Bevere, Mario De Bellis, Laura Alaimo, Elena Sapuppo, Francesca Masetto, Aldo Mombello, Michele Simbolo, Elena Bariani, Michele Milella, Matteo Fassan, Aldo Scarpa, Claudio Luchini
Summary: Pancreatic ductal adenocarcinoma (PDAC) and distal cholangiocarcinoma (dCCA) are aggressive tumors with limited treatment options. They share histomolecular features, making differential diagnosis challenging, but also have significant differences with clinical implications. PDAC and dCCA have different prognosis and oncogenic targets, highlighting the importance of accurate diagnosis and targeted treatments.
Review
Biochemistry & Molecular Biology
Tais Boeira Biazus, Gabriel Henrique Beraldi, Lucas Tokeshi, Luisa de Siqueira Rotenberg, Elena Dragioti, Andre F. Carvalho, Marco Solmi, Beny Lafer
Summary: The results of this systematic review and meta-analysis show that the risk of premature death in patients with bipolar disorder is not only related to suicide and unnatural causes, but also to physical comorbidities. Therefore, in addition to suicide prevention, promoting physical health and preventing physical conditions in individuals with bipolar disorder may reduce premature mortality risk.
MOLECULAR PSYCHIATRY
(2023)
Review
Oncology
Amanda Casirati, Valentina Da Prat, Arianna Bettiga, Lucia Aretano, Francesco Trevisani, Emanuele Cereda, Alberto Briganti, Elisa Colombo, Giorgia Preziati, Francesca De Simeis, Andrea Salonia, Francesco Montorsi, Riccardo Caccialanza, Richard Naspro
Summary: Preoperative nutritional status is crucial in cancer patients undergoing radical cystectomy, as malnutrition increases the risk of post-surgical complications. Muscle mass loss, a major consequence of cancer-related malnutrition, is associated with readmission, longer hospital stays, and higher mortality rates. Immunonutrition, using specific nutrients to boost the immune system, shows promising evidence in reducing complications after bladder surgery. Further research is needed to determine the optimal approach for improving patient outcomes and establish the effectiveness of perioperative immunonutrition.
Article
Rheumatology
Toby Smith, Gurpreet Singh, George Mcnamee, Christopher Newton
Summary: This study investigated the current practices for discharging people with low back pain (LBP) from physiotherapy services in the UK. Majority of physiotherapists used a shared decision-making and person-physiotherapist goal attainment approach to discharge patients with LBP. Some suggested that using a patient-initiated follow-up or graded discharge approach may be more suitable for patients at higher risk of pain flare or with low self-efficacy.
MUSCULOSKELETAL CARE
(2024)
Review
Clinical Neurology
Monika Zawadka-Kunikowska, Lukasz Rzepinski, Malgorzata Tafil-Klawe, Nicola Veronese, Mario Barbagallo, Mario Habek, Nils E. Gilhus
Summary: There are differences in cardiovascular autonomic parameters between patients with myasthenia gravis (MG) and healthy controls (HCs), including altered cardiac autonomic function in MG patients.
NEUROLOGY INTERNATIONAL
(2023)
Article
Rheumatology
Walter P. Maksymowych, Nele Herregods, Nisha Varma, Arthur B. Meyers, Jennifer Stimec, Andrea S. Doria, Nikolay Tzaribachev, Tarimobo M. Otobo, Marion A. van Rossum, Joel Paschke, Stephanie Wichuk, Robert G. Lambert
Summary: This study aimed to investigate whether systematic calibration improves the scoring proficiency of JAMRIS-SIJ and whether contrast-enhancement enhances its performance. The results showed that calibrated readers achieved greater reliability in scoring specific inflammatory and structural lesions. Sensitivity and reliability for scoring inflammatory lesions were higher on fluid-sensitive sequences compared to contrast-enhanced sequences. Therefore, systematic calibration should be implemented before using JAMRIS-SIJ in clinical trials, and it is unlikely that contrast-enhanced MRI will improve the performance of this method.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2024)
Article
Rheumatology
L. van Ouwerkerk, S. A. Bergstra, T. D. Maarseveen, T. W. J. Huizinga, R. Knevel, C. F. Allaart
Summary: This study evaluated whether the initial use of glucocorticoid (GC) bridging in RA patients leads to a higher probability of long-term GC and bDMARD use. The results showed that patients who initially started GC had a higher risk of later GC use, but the risk of bDMARD use was not significantly increased.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2024)
Article
Rheumatology
ShuangHua Liu, YiMei Tan, WeiDong Huang, HongSheng Luo, BingCheng Pan, Shuan Wu
Summary: This study assessed the cardiovascular safety of zoledronic acid in the treatment of primary osteoporosis. The results showed that in women with primary osteoporosis, zoledronic acid may increase the risk of atrial fibrillation and arrhythmias, but the cardiovascular risk in men with osteoporosis is uncertain.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2024)