Article
Oncology
Isabelle Soerjomataram, Citadel Cabasag, Aude Bardot, Miranda Marie Fidler-Benaoudia, Adalberto Miranda-Filho, Jacques Ferlay, Donald Maxwell Parkin, Rama Ranganathan, Marion Pineros, Ariana Znaor, Les Mery, Yvonne Walburga Joko-Fru, Rajesh Dikshit, Rengaswamy Sankaranarayanan, Rajaraman Swaminathan, Freddie Bray
Summary: SURVCAN-3 is an international collaboration that aims to benchmark cancer survival rates in different regions and link them to health systems and human development. The study found significant disparities in cancer survival rates across countries, which are associated with a country's development level and the availability of health services.
Article
Cardiac & Cardiovascular Systems
Philip Joseph, Vellappillil Raman Kutty, Viswanathan Mohan, Rajesh Kumar, Prem Mony, Krishnapillai Vijayakumar, Shofiqul Islam, Romaina Iqbal, Khawar Kazmi, Omar Rahman, Rita Yusuf, Ranjit Mohan Anjana, Indu Mohan, Sumathy Rangarajan, Rajeev Gupta, Salim Yusuf
Summary: Rates of cardiovascular disease and mortality are highest in rural areas and among men in South Asia, with modifiable risk factors contributing significantly to the incidence of both outcomes.
EUROPEAN HEART JOURNAL
(2022)
Article
Endocrinology & Metabolism
Jung Hwan Park, Kyoung Hwa Ha, Bo Yeon Kim, Jae Hyuk Lee, Dae Jung Kim
Summary: From 2006 to 2015, hospitalization rates for major cardiovascular complications decreased in South Korean diabetes patients, while rates for heart failure and peripheral artery disease increased. From 2007 to 2015, mortality rates for cancer, cerebrovascular disease, diabetes, heart disease, and hypertensive disease decreased, but mortality rate for pneumonia increased. Overall, there was a continuous reduction in cardiovascular complications and mortality in adults with diabetes, but efforts are needed to prevent certain diabetes complications.
DIABETES & METABOLISM JOURNAL
(2021)
Article
Multidisciplinary Sciences
Fanny Simoes, Charles Bouveyron, Damien Piga, Damien Borel, Stephane Descombes, Veronique Paquis-Flucklinger, Jaques Levraut, Pierre Gibelin, Silvia Bottini
Summary: The study suggests that environmental pollution may play a role in triggering diseases such as cardiac dyspnea. Pollutants have a significant impact on short-term exposure and have different exposure curve shapes.
SCIENTIFIC REPORTS
(2022)
Review
Public, Environmental & Occupational Health
Alexandra Giraldo-Osorio, Monica Perez-Rios, Julia Rey-Brandariz, Leonor Varela-Lema, Agustin Montes, Adriana Rodriguez-R, Nerea Mourino, Alberto Ruano-Ravina
Summary: Various studies estimating smoking-attributable mortality (SAM) have been conducted in South American countries, with Argentina having the highest number of estimates. Regardless of the country and time period, male smokers consistently show higher SAM figures than female smokers. The burden of SAM is highest for cardiovascular diseases in the region. Further research is needed to update the impact of smoking on all countries across South America for effective policy-making.
JOURNAL OF GLOBAL HEALTH
(2021)
Article
Cardiac & Cardiovascular Systems
Bin Zhang, Zhi-Fei Li, Zhuo-Yu An, Li Zhang, Jing-Yi Wang, Meng-Di Hao, Yi-Jing Jin, Dong Li, An-Jian Song, Qiang Ren, Wen-Biao Chen
Summary: The study found that asthma patients have an increased risk of cardiovascular disease morbidity and mortality, as well as all-cause mortality. Female asthma patients have a higher risk of cardiovascular disease morbidity and all-cause mortality, and late-onset asthma patients have a higher risk of cardiovascular disease morbidity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
J. M. Yun, S. Choi, K. Kim, S. M. Kim, J. S. Son, G. Lee, S-M Jeong, S. Y. Park, Y-Y Kim, S. M. Park
Summary: The study found that among young adults, those who underwent health screenings had lower risk for all-cause mortality, CVD mortality, and hospitalization of CVD compared to non-attenders.
Article
Public, Environmental & Occupational Health
P. R. Vieira de Oliveira Salerno, C. Briones-Valdivieso, I. Motairek, L. A. Palma Dallan, S. Rajagopalan, S. V. Deo, F. Petermann-Rocha, S. Al-Kindi
Summary: The study explores the impact of PM2.5 exposure, household air pollution (HAP), and ambient air pollution (AAP) on cardiovascular disease (CVD) mortality and disability-adjusted life years (DALYs) in South American countries from 1990 to 2019. The findings reveal a significant impact of air pollution on CVD in South America, with regional heterogeneity in the absolute change of PM2.5 concentration levels. AAP was found to be the greatest contributor to the CVD burden in the region.
Article
Cardiac & Cardiovascular Systems
Jiang-lin Wang, Wen-jun Yin, Ling-yun Zhou, Ya-feng Wang, Xiao-cong Zuo
Summary: Smoking status, intensity, duration of smoking cessation, and age of smoking initiation all have significant impacts on the risk of all-cause and cause-specific mortality among cardiovascular disease patients, with smokers having higher risks of mortality but a significant decrease after quitting smoking.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Sadiya S. Khan, Hongyan Ning, Arjun Sinha, John Wilkins, Norrina B. Allen, Thanh Huyen T. Vu, Jarett D. Berry, Donald M. Lloyd-Jones, Ranya Sweis
Summary: This study found that smoking is significantly associated with premature death, whether related to cardiovascular disease or not. Smoking not only increases the risk of cardiovascular disease, but also leads to an earlier onset of cardiovascular disease.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Multidisciplinary Sciences
Gudrun Hoskuldsdottir, Stefan Franzen, Katarina Eeg-Olofsson, Bjorn Eliasson
Summary: This study aimed to explore the development risk of comorbidities in type 2 diabetes patients and evaluate the impact of common risk factors. The study found that all comorbidities gradually increased over time, with women having a lower risk compared to men.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Jonas Tagt, Emilie Helte, Carolina Donat-Vargas, Susanna C. Larsson, Karl Michaelsson, Alicja Wolk, Marie Vahter, Maria Kippler, Agneta Akesson
Summary: This study assessed the association of urinary cadmium (U-Cd) with fractures, myocardial infarction, heart failure, ischemic stroke, and mortality in postmenopausal women. The results indicated that long-term cadmium exposure might be associated with increased risk of fractures and all-cause mortality at lower levels than previously suggested.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Cardiac & Cardiovascular Systems
Chao Zeng, Lynn Rosenberg, Xiaoxiao Li, Luc Djousse, Jie Wei, Guanghua Lei, Yuqing Zhang
Summary: This study found that the initiation of sodium-containing acetaminophen is associated with increased risks of cardiovascular disease and all-cause mortality among both individuals with and without hypertension. It suggests that individuals should avoid unnecessary excessive sodium intake through sodium-containing acetaminophen use.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Jawad H. Butt, Emil L. Fosbol, Thomas A. Gerds, Charlotte Andersson, Kristian Kragholm, Tor Biering-Sorensen, Julie Andersen, Mathew Phelps, Mikkel Porsborg Andersen, Gunnar Gislason, Christian Torp-Pedersen, Lars Kober, Morten Schou
Summary: A study investigated mortality rates in patients with established cardiovascular disease in Denmark during the nationwide lockdown in 2020. It found that before the lockdown, mortality rates were significantly lower in 2020 compared to 2019, and during and after the lockdown the overall mortality rate was not significantly different. However, in-hospital mortality rate was lower and out-of-hospital mortality rate was higher during and after lockdown compared to the same period in 2019.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Peter Kokkinos, Charles Faselis, Immanuel Babu Henry Samuel, Carl J. Lavie, Jiajia Zhang, Jose D. Vargas, Andreas Pittaras, Michael Doumas, Pamela Karasik, Hans Moore, Michael Heimal, Jonathan Myers
Summary: This study evaluated the association between cardiorespiratory fitness and mortality risk and found that changes in cardiorespiratory fitness were inversely proportional to mortality risk. The results suggest that even small changes in cardiorespiratory fitness have a significant impact on mortality risk.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Peripheral Vascular Disease
Nicolas Renna, Daniel Piskorz, Diego Stisman, Diego Martinez, Ludmila Lescano, Sergio Vissani, Walter Espeche, Diego Marquez, Roberto Parodi, Diego Naninni, Marcos Baroni, Daniel Llanos, Rocio Martinez, Jessica Barochinner, Gustavo Staffieri, Fernando Lanas, Monica Velasquez, Marcos Marin, Bryan Williams, Irene Ennis
Summary: This document provides a comprehensive review of the scientific evidence on the use of single pill combinations (SPCs) in the treatment of hypertension. It highlights the importance of using multiple drugs to achieve blood pressure goals and the inverse relationship between treatment adherence and the number of drugs taken. The document also discusses the effectiveness and adverse effects of SPCs, their use in special populations, and their impact on hypertensive-mediated organ damage.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Cardiac & Cardiovascular Systems
Jaffar Al-Sheikhli, Ian Patchett, Ven Gee Lim, Leeann Marshall, Will Foster, Michael Kuehl, Shamil Yusuf, Sandeep Panikker, Kiran Patel, Faizel Osman, Prithwish Banerjee, Nicolas Lellouche, Tarvinder Dhanjal
Summary: The feasibility study of using the DiamondTemp ablation (DTA) catheter system for ventricular tachycardia (VT) ablation in ischaemic cardiomyopathy (ICM) patients showed significant improvements in patient condition and clinical outcomes.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Sylvia Haas, John A. Camm, Darius Harald, Jan Steffel, Saverio Virdone, Karen Pieper, Marianne Brodmann, Sebastian Schellong, Frank Misselwitz, Gloria Kayani, Ajay K. Kakkar
Summary: There are similarities and dissimilarities in AF management and clinical outcomes between DACH and ORW regions. The increased use of NOACs in DACH is associated with a mismatch in risk-adapted anticoagulation. Suboptimal control of INR is observed in both regions. DACH region has higher rates of cardiovascular death and lower rates of non-haemorrhagic stroke.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Clinical Neurology
Andrew Smyth, Martin O'Donnell, Sumathy Rangarajan, Graeme J. Hankey, Shahram Oveisgharan, Michelle Canavan, Clodagh McDermott, Denis Xavier, Hongye Zhang, Albertino Damasceno, Alvaro Avezum, Nana Pogosova, Aytekin Oguz, Danuta Ryglewicz, Helle Klingenberg Iversen, Fernando Lanas, Annika Rosengren, Salim Yusuf, Peter Langhorne
Summary: This study examined the association between alcohol consumption and stroke in a large international population. It found that high and moderate alcohol intake increased the odds of stroke, while low intake was not associated with stroke. However, there were regional variations in the relationship.
Review
Public, Environmental & Occupational Health
Edgar D. Hernandez, Elisa A. Cobo, Lawrence P. Cahalin, Pamela Seron
Summary: This study aimed to determine the effectiveness of structural-level environmental interventions on changes in physical activity (PA) levels in populations. A literature search was conducted to include natural experiments with structural modifications, and the results showed that such interventions can improve PA levels, with the greatest effect observed in parks and active transportation.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2023)
Article
Peripheral Vascular Disease
Daniel D. Cohen, Gustavo Aroca-Martinez, Javier Carreno-Robayo, Alvaro Castaneda-Hernandez, Yaneth Herazo-Beltran, Paul A. Camacho, Johanna Otero, Daniel Martinez-Bello, Jose P. Lopez-Lopez, Patricio Lopez-Jaramillo
Summary: Isometric handgrip or (wall) squat exercise performed three times per week reduces systolic blood pressure in adults with hypertension. Comparing the two interventions, the wall squat appears to be more effective in maintaining benefits with a minimal training dose. This low-cost, time-efficient intervention has promising potential for public health settings.
JOURNAL OF CLINICAL HYPERTENSION
(2023)
Article
Cardiac & Cardiovascular Systems
Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan, Martin O'Donnell, Weihong Hu, Gilles Dagenais, Andreas Wielgosz, Scott A. Lear, Li Wei, Rafael Diaz, Alvaro Avezum, Patricio Lopez-Jaramillo, Fernando Lanas, Sumathi Swaminathan, Manmeet Kaur, K. Vijayakumar, Viswanathan Mohan, Rajeev Gupta, Andrzej Szuba, Romaina Iqbal, Rita Yusuf, Noushin Mohammadifard, Rasha Khatib, Nafiza Mat Nasir, Kubilay Karsidag, Annika Rosengren, Afzalhussein Yusufali, Edelweiss Wentzel-Viljoen, Jephat Chifamba, Antonio Dans, Khalid F. Alhabib, Karen Yeates, Koon Teo, Hertzel C. Gerstein, Salim Yusuf
Summary: A healthy diet score based on fruits, vegetables, nuts, legumes, fish, and whole-fat dairy is associated with lower risk of all-cause mortality, cardiovascular disease, myocardial infarction, and stroke in a global population. This score exhibits stronger associations with death or CVD compared to other common diet scores.
EUROPEAN HEART JOURNAL
(2023)
Article
Public, Environmental & Occupational Health
Maria Khan, Mohammad Wasay, Martin James O'Donnell, Romaina Iqbal, Peter Langhorne, Annika Rosengren, Albertino Damasceno, Aytekin Oguz, Fernando Lanas, Nana Pogosova, Fawaz Alhussain, Shahram Oveisgharan, Anna Czlonkowska, Danuta Ryglewicz, Salim Yusuf
Summary: Cardiac causes, binge drinking, hypertension, increased waist-to-hip ratio, psychosocial stress, smoking, and certain lipid levels are important risk factors for ischemic stroke in individuals under 45 years of age. For intracerebral hemorrhage, only hypertension and binge drinking are significant risk factors in this age group. Hypertension is the most significant risk factor for stroke in all age groups and regions.
Article
Medicine, General & Internal
Ruvistay Gutierrez-Arias, Dawid Pieper, Peter Nydahl, Felipe Gonzalez-Seguel, Yorschua Jalil, Maria-Jose Oliveros, Rodrigo Torres-Castro, Pamela Seron
Summary: This study aims to evaluate the redundancy, methodological and reporting quality, and potential reasons for discordance in systematic reviews (SRs) conducted to determine the effectiveness of early mobilisation in critically ill adult patients. Through searching multiple databases, reviewing literature and assessing the quality of studies, the effectiveness of this intervention will be explored. Findings of this study will be disseminated at conferences and published in a peer-reviewed journal.
Article
Cardiac & Cardiovascular Systems
Gustavo A. Lemus Barrios, Jose P. Lopez-Lopez, Stephany Barbosa-Balaguera, Alejandro Marino Correa
Summary: This is a case of acute onset heart failure in a 49-year-old man, diagnosed as a left-dominant DSP arrhythmogenic cardiomyopathy mutation after a series of examinations and differential diagnoses.
Article
Environmental Sciences
Gabriel A. Rojas, Nicolas Saavedra, Cristian Morales, Kathleen Saavedra, Fernando Lanas, Luis A. Salazar
Summary: This study found that exercise can modulate serum inflammatory cytokines, gene expression related to endothelial dysfunction and REDOX imbalance, as well as the protein expression of ICAM-1 and VCAM-1. These findings suggest that exercise may help mitigate the adverse effects of PAHs present in air pollution.
Article
Medicine, General & Internal
Giulio Francesco Romiti, Bernadette Corica, Marco Proietti, Davide Antonio Mei, Juliane Frydenlund, Arnaud Bisson, Giuseppe Boriani, Brian Olshansky, Yi-Hsin Chan, Menno V. Huisman, Tze-Fan Chao, Gregory Y. H. Lip
Summary: This study aims to analyze the risk of oral anticoagulant prescription, discontinuation, and adverse outcomes in Asian patients with atrial fibrillation, and finds that they have suboptimal thromboembolic risk management and specific risk profiles of adverse outcomes.
Article
Biochemistry & Molecular Biology
Cristian Morales, Raul Arias-Carrasco, Vinicius Maracaja-Coutinho, Pamela Seron, Fernando Lanas, Luis A. Salazar, Nicolas Saavedra
Summary: This study aimed to identify differences in bacterial small RNAs between hypercholesterolemic and normocholesterolemic individuals at the gut level. Most of the small RNAs were of bacterial origin and had a higher number of readings in normocholesterolemic participants. Small RNA ID 2909606 associated with Coprococcus eutactus and small RNA ID 2149569 from the species Blautia wexlerae were upregulated in hypercholesterolemic subjects, and other bacterial and archaeal small RNAs interacting with the LDL receptor were identified.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Letter
Peripheral Vascular Disease
Jorge Andres Delgado-Ron, Patricio Lopez-Jaramillo, Mohammad Ehsanul Karim
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Geriatrics & Gerontology
Patricio Lopez-Jaramillo, Diego Gomez-Arbelaez, Daniel Martinez-Bello, Marc Evans M. Abat, Khalid F. Alhabib, Alvaro Avezum, Olga Barbarash, Jephat Chifamba, Maria L. Diaz, Sadi Gulec, Noorhassim Ismail, Romaina Iqbal, Roya Kelishadi, Rasha Khatib, Fernando Lanas, Naomi S. Levitt, Yang Li, Viswanathan Mohan, Prem K. Mony, Paul Poirier, Annika Rosengren, Biju Soman, Chuangshi Wang, Yang Wang, Karen Yeates, Rita Yusuf, Afzalhussein Yusufali, Katarzyna Zatonska, Sumathy Rangarajan, Salim Yusuf
Summary: The TyG index is associated with cardiovascular diseases and mortality, especially in Asia. It is significantly related to the risk of cardiovascular diseases, myocardial infarction, stroke, and type 2 diabetes, indicating that insulin resistance plays a promoting role in the development of these diseases.
LANCET HEALTHY LONGEVITY
(2023)