The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling

One Hormone, Two Actions: Anti- and Pro-Inflammatory Effects of Glucocorticoids

(2015) Diana Cruz-Topete et al.   NEUROIMMUNOMODULATION

Selective inhibitors of the FK506-binding protein 51 by induced fit

(2014) Steffen Gaali et al.   Nature Chemical Biology

TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling

(2014) Ying Lu et al.   PAIN

No man is an island: Living in a disadvantaged neighborhood influences chronic pain development after motor vehicle collision

(2014) Jacob C. Ulirsch et al.   PAIN

Alterations in DNA methylation of Fkbp5 as a determinant of blood–brain correlation of glucocorticoid exposure

(2014) Erin R. Ewald et al.   PSYCHONEUROENDOCRINOLOGY

Gene-environment interactions at theFKBP5locus: sensitive periods, mechanisms and pleiotropism

(2013) A. S. Zannas et al.   GENES BRAIN AND BEHAVIOR

The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

(2013) Robert H. Oakley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure

(2013) Andrey V. Bortsov et al.   PAIN

The Prospect of FKBP51 as a Drug Target

(2012) Mathias V. Schmidt et al.   ChemMedChem

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

Estimating Efficacy and Drug ED50's Using von Frey Thresholds: Impact of Weber's Law and Log Transformation

(2012) Charles Mills et al.   JOURNAL OF PAIN

The Expression of Spinal Methyl-CpG-Binding Protein 2, DNA Methyltransferases and Histone Deacetylases is Modulated in Persistent Pain States

(2012) Keri K Tochiki et al.   Molecular Pain

P2X4R+ microglia drive neuropathic pain

(2012) Simon Beggs et al.   NATURE NEUROSCIENCE

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior

(2011) Chadi Touma et al.   BIOLOGICAL PSYCHIATRY

Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity

(2011) Simon Beggs et al.   BRAIN

Steroid up-regulation of FKBP51 and its role in hormone signaling

(2011) Tiina Jääskeläinen et al.   CURRENT OPINION IN PHARMACOLOGY

FKBP51—a selective modulator of glucocorticoid and androgen sensitivity

(2011) Lance A Stechschulte et al.   CURRENT OPINION IN PHARMACOLOGY

Glucocorticoid-independent Repression of Tumor Necrosis Factor (TNF) α-stimulated Interleukin (IL)-6 Expression by the Glucocorticoid Receptor

(2011) Nicolette J. D. Verhoog et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress

(2011) Jakob Hartmann et al.   NEUROPHARMACOLOGY

A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51

(2011) John C. O'Leary et al.   PLoS One

Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation ofFkbp5in Mice

(2010) Richard S. Lee et al.   ENDOCRINOLOGY

Discovery of Glucocorticoid Receptor-β in Mice with a Role in Metabolism

(2010) Terry D. Hinds et al.   MOLECULAR ENDOCRINOLOGY

Glucocorticoid Receptor Activates PoisedFKBP51Locus through Long-Distance Interactions

(2010) Ville Paakinaho et al.   MOLECULAR ENDOCRINOLOGY

Hindpaw incision in early life increases the hyperalgesic response to repeat surgical injury: Critical period and dependence on initial afferent activity

(2009) Suellen M. Walker et al.   PAIN

Descending Serotonergic Controls Regulate Inflammation-Induced Mechanical Sensitivity and Methyl-CpG-Binding Protein 2 Phosphorylation in the Rat Superficial Dorsal Horn

(2008) Sandrine M Géranton et al.   Molecular Pain