Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling
出版年份 2016 全文链接
标题
Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling
作者
关键词
lactic acid, NKT cell, IFNγ, mTOR, PLZF
出版物
Science China-Life Sciences
Volume 59, Issue 12, Pages 1290-1296
出版商
Springer Nature
发表日期
2016-12-19
DOI
10.1007/s11427-016-0348-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
- (2016) Soumaya Kouidhi et al. Frontiers in Immunology
- T Cells and Cancer: How Metabolism Shapes Immunity
- (2016) Barbara Molon et al. Frontiers in Immunology
- Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance
- (2016) Susana Romero-Garcia et al. Frontiers in Immunology
- Lactic acid delays the inflammatory response of human monocytes
- (2015) Katrin Peter et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- Intratumoral dendritic cells in the anti-tumor immune response
- (2015) Yang Liu et al. Cellular & Molecular Immunology
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- Regulation of T cells by mTOR: the known knowns and the known unknowns
- (2015) Kristen N. Pollizzi et al. TRENDS IN IMMUNOLOGY
- Effect of everolimus on the immunomodulation of the human neutrophil inflammatory response and activation
- (2014) Damien Vitiello et al. Cellular & Molecular Immunology
- Mammalian Target of Rapamycin Complex 2 Regulates Invariant NKT Cell Development and Function Independent of Promyelocytic Leukemia Zinc-Finger
- (2014) Nicolas Prevot et al. JOURNAL OF IMMUNOLOGY
- Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function
- (2014) J. Shin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Metabolic control of the Treg/Th17 axis
- (2013) Joseph Barbi et al. IMMUNOLOGICAL REVIEWS
- Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
- (2013) Madhusudhanan Sukumar et al. JOURNAL OF CLINICAL INVESTIGATION
- NKT Cells as an Ideal Anti-Tumor Immunotherapeutic
- (2013) Shin-ichiro Fujii et al. Frontiers in Immunology
- Regulation of Immune Responses by mTOR
- (2012) Jonathan D. Powell et al. Annual Review of Immunology
- Distinct APCs Explain the Cytokine Bias of -Galactosylceramide Variants In Vivo
- (2012) L. Bai et al. JOURNAL OF IMMUNOLOGY
- Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer
- (2011) Shinichiro Motohashi et al. CLINICAL IMMUNOLOGY
- Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
- (2011) Gerritje J.W. van der Windt et al. IMMUNITY
- Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation
- (2011) Seth T. Scanlon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes
- (2009) K. Dietl et al. JOURNAL OF IMMUNOLOGY
- A Phase I-II Study of -Galactosylceramide-Pulsed IL-2/GM-CSF-Cultured Peripheral Blood Mononuclear Cells in Patients with Advanced and Recurrent Non-Small Cell Lung Cancer
- (2009) S. Motohashi et al. JOURNAL OF IMMUNOLOGY
- Enhancing CD8 T-cell memory by modulating fatty acid metabolism
- (2009) Erika L. Pearce et al. NATURE
- Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen GalCer
- (2009) L. Bai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage
- (2008) Adam K. Savage et al. IMMUNITY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started