Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA
出版年份 2016 全文链接
标题
Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA
作者
关键词
-
出版物
SCIENCE
Volume 352, Issue 6283, Pages 309-312
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-04-15
DOI
10.1126/science.aad5367
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Glycyl radical activating enzymes: Structure, mechanism, and substrate interactions
- (2014) Krista A. Shisler et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Mechanistic Diversity of RadicalS-Adenosylmethionine (SAM)-dependent Methylation
- (2014) Matthew R. Bauerle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN
- (2014) Alexey Silakov et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Chemically Competent Thiosulfuranyl Radical on the Escherichia coli Class III Ribonucleotide Reductase
- (2014) Yifeng Wei et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Distinction between the Cfr Methyltransferase Conferring Antibiotic Resistance and the Housekeeping RlmN Methyltransferase
- (2013) Gemma C. Atkinson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr
- (2013) Tyler L Grove et al. Nature Chemical Biology
- RCrane: semi-automated RNA model building
- (2012) Kevin S. Keating et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- JLigand: a graphical tool for theCCP4 template-restraint library
- (2012) Andrey A. Lebedev et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Covalent Intermediate in the Catalytic Mechanism of the Radical S-Adenosyl-l-methionine Methyl Synthase RlmN Trapped by Mutagenesis
- (2012) Kevin P. McCusker et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy
- (2012) A. Benitez-Paez et al. RNA
- Cfr and RlmN Contain a Single [4Fe-4S] Cluster, which Directs Two Distinct Reactivities forS-Adenosylmethionine: Methyl Transfer by SN2 Displacement and Radical Generation
- (2011) Tyler L. Grove et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center
- (2011) Haripriya Ramu et al. MOLECULAR CELL
- RNA methylation by Radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift
- (2011) F. Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Radically Different Mechanism for S-Adenosylmethionine-Dependent Methyltransferases
- (2011) T. L. Grove et al. SCIENCE
- Structural Basis for Methyl Transfer by a Radical SAM Enzyme
- (2011) A. K. Boal et al. SCIENCE
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Resistance to Linezolid Is Mediated by thecfrGene in the First Report of an Outbreak of Linezolid‐ResistantStaphylococcus aureus
- (2010) Gracia Morales et al. CLINICAL INFECTIOUS DISEASES
- The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide
- (2010) Nora Vázquez-Laslop et al. EMBO JOURNAL
- RlmN and Cfr are Radical SAM Enzymes Involved in Methylation of Ribosomal RNA
- (2010) Feng Yan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Snapshots of Dynamics in SynthesizingN6-Isopentenyladenosine at the tRNA Anticodon
- (2009) Sarin Chimnaronk et al. BIOCHEMISTRY
- Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria
- (2009) A. M. B. Giessing et al. RNA
- Transcriptional and Translational Control of the mlr Operon, Which Confers Resistance to Seven Classes of Protein Synthesis Inhibitors
- (2008) L. K. Smith et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structure, dynamics, and function of RNA modification enzymes
- (2008) Ryuichiro Ishitani et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now