Histone availability as a strategy to control gene expression

Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II

(2016) Fernando Carrillo Oesterreich et al.   CELL

Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging

(2015) Sofía A. Rodríguez et al.   AGING CELL

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A positioned +1 nucleosome enhances promoter-proximal pausing

(2015) Silvia Jimeno-González et al.   NUCLEIC ACIDS RESEARCH

Defective histone supply causes changes in RNA polymerase II elongation rate and cotranscriptional pre-mRNA splicing

(2015) Silvia Jimeno-González et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia

(2014) Taranjit Singh Rai et al.   GENES & DEVELOPMENT

Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate

(2014) Nova Fong et al.   GENES & DEVELOPMENT

Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging

(2014) Z. Hu et al.   GENES & DEVELOPMENT

Fidelity of Histone Gene Regulation Is Obligatory for Genome Replication and Stability

(2014) P. N. Ghule et al.   MOLECULAR AND CELLULAR BIOLOGY

How Slow RNA Polymerase II Elongation Favors Alternative Exon Skipping

(2014) Gwendal Dujardin et al.   MOLECULAR CELL

Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1

(2014) Roderick J O'Sullivan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Defective histone supply causes condensin-dependent chromatin alterations, SAC activation and chromosome decatenation impairment

(2014) Marina Murillo-Pineda et al.   NUCLEIC ACIDS RESEARCH

Histone content increases in differentiating embryonic stem cells

(2014) Theodoros Karnavas et al.   Frontiers in Physiology

Control of Transcriptional Elongation

(2013) Hojoong Kwak et al.   Annual Review of Genetics

H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin

(2013) P. Chen et al.   GENES & DEVELOPMENT

Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence

(2013) J. M. Platt et al.   GENES & DEVELOPMENT

New histone supply regulates replication fork speed and PCNA unloading

(2013) Jakob Mejlvang et al.   JOURNAL OF CELL BIOLOGY

Lysosome-mediated processing of chromatin in senescence

(2013) Andre Ivanov et al.   JOURNAL OF CELL BIOLOGY

Changes in splicing factor expression are associated with advancing age in man

(2013) Alice C. Holly et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Widespread splicing changes in human brain development and aging

(2013) P. Mazin et al.   Molecular Systems Biology

Chromatin Modifications as Determinants of Muscle Stem Cell Quiescence and Chronological Aging

(2013) Ling Liu et al.   Cell Reports

Histone dosage regulates DNA damage sensitivity in a checkpoint-independent manner by the homologous recombination pathway

(2012) D. Liang et al.   NUCLEIC ACIDS RESEARCH

The great unravelling: chromatin as a modulator of the aging process

(2012) Roderick J. O'Sullivan et al.   TRENDS IN BIOCHEMICAL SCIENCES

In Vivo Effects of Histone H3 Depletion on Nucleosome Occupancy and Position in Saccharomyces cerevisiae

(2012) Andrea J. Gossett et al.   PLoS Genetics

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

(2011) Lorna W. Harries et al.   AGING CELL

Regulation of alternative splicing by the core spliceosomal machinery

(2011) A. L. Saltzman et al.   GENES & DEVELOPMENT

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain

(2011) J. R. Tollervey et al.   GENOME RESEARCH

Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks

(2011) Marta Clemente-Ruiz et al.   PLoS Genetics

Nucleosomes are preferentially positioned at exons in somatic and sperm cells

(2010) Satu Nahkuri et al.   CELL CYCLE

BRG1 helps RNA polymerase II to overcome a nucleosomal barrier during elongation, in vivo

(2010) Alicia Subtil-Rodríguez et al.   EMBO REPORTS

Elevated Histone Expression Promotes Life Span Extension

(2010) Jason Feser et al.   MOLECULAR CELL

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

(2010) Roderick J O'Sullivan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin assembly controls replication fork stability

(2009) Marta Clemente-Ruiz et al.   EMBO REPORTS

Nucleosomes are well positioned in exons and carry characteristic histone modifications

(2009) R. Andersson et al.   GENOME RESEARCH

Biased Chromatin Signatures around Polyadenylation Sites and Exons

(2009) Noah Spies et al.   MOLECULAR CELL

Nucleosome positioning as a determinant of exon recognition

(2009) Hagen Tilgner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin organization marks exon-intron structure

(2009) Schraga Schwartz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Knockdown of SLBP results in nuclear retention of histone mRNA

(2009) K. D. Sullivan et al.   RNA

Nucleosomal Fluctuations Govern the Transcription Dynamics of RNA Polymerase II

(2009) C. Hodges et al.   SCIENCE

Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay

(2008) A. L. Saltzman et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

(2008) William F. Marzluff et al.   NATURE REVIEWS GENETICS

Human T Lymphotropic Virus Type 1 protein Tax reduces histone levels

(2008) James M Bogenberger et al.   Retrovirology

Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information

(2008) Armelle Corpet et al.   TRENDS IN CELL BIOLOGY