Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging

Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development

(2013) Tomás McKenna et al.   AGING CELL

Changes in splicing factor expression are associated with advancing age in man

(2013) Alice C. Holly et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Widespread splicing changes in human brain development and aging

(2013) P. Mazin et al.   Molecular Systems Biology

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome

(2012) R. P. McCord et al.   GENOME RESEARCH

Pre-mRNA splicing in disease and therapeutics

(2012) Ravi K. Singh et al.   TRENDS IN MOLECULAR MEDICINE

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

(2011) Lorna W. Harries et al.   AGING CELL

Stem cell depletion in Hutchinson-Gilford progeria syndrome

(2011) Ylva Rosengardten et al.   AGING CELL

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain

(2011) J. R. Tollervey et al.   GENOME RESEARCH

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

(2011) Kan Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased expression of the Hutchinson–Gilford progeria syndrome truncated lamin A transcript during cell aging

(2009) Sofia Rodriguez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Life Span Extension in Mice by Food Restriction Depends on an Energy Imbalance

(2009) Rajindar S. Sohal et al.   JOURNAL OF NUTRITION

Single-molecule analysis of protein-free U2–U6 snRNAs

(2009) Zhuojun Guo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Overestimation of alternative splicing caused by variable probe characteristics in exon arrays

(2009) Dimos Gaidatzis et al.   NUCLEIC ACIDS RESEARCH

Differential Expression of A-Type and B-Type Lamins during Hair Cycling

(2009) Mubashir Hanif et al.   PLoS One

Microarray analysis reveals similarity between CD8+CD28− T cells from young and elderly persons, but not of CD8+CD28+ T cells

(2008) Lutfan Lazuardi et al.   BIOGERONTOLOGY

Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease

(2008) H. Sagelius et al.   JOURNAL OF CELL SCIENCE

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY