Large-scale multiplex absolute protein quantification of drug-metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH-MS: Comparison with MRM/SRM and HR-MRM/PRM

Application of an LC–MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique

(2015) M.D. Harwood et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quantitative ADME Proteomics – CYP and UGT Enzymes in the Beagle Dog Liver and Intestine

(2014) Aki T. Heikkinen et al.   PHARMACEUTICAL RESEARCH

A novel link between Slc22a18 and fat accumulation revealed by a mutation in the spontaneously hypertensive rat

(2013) Takashi Yamamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mass spectrometric protein maps for biomarker discovery and clinical research

(2013) Yansheng Liu et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Targeted Quantitative Proteomics for the Analysis of 14 UGT1As and -2Bs in Human Liver Using NanoUPLC–MS/MS with Selected Reaction Monitoring

(2013) John K. Fallon et al.   JOURNAL OF PROTEOME RESEARCH

Transporter biology in drug approval: Regulatory aspects

(2013) Kazuya Maeda et al.   MOLECULAR ASPECTS OF MEDICINE

Quantitative measurements ofN-linked glycoproteins in human plasma by SWATH-MS

(2013) Yansheng Liu et al.   PROTEOMICS

UGT2B17 Genetic Polymorphisms Dramatically Affect the Pharmacokinetics of MK-7246 in Healthy Subjects in a First-in-Human Study

(2012) Y-H Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis

(2012) Ludovic C. Gillet et al.   MOLECULAR & CELLULAR PROTEOMICS

Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function

(2011) Ravi M. Patel et al.   AMERICAN JOURNAL OF PATHOLOGY

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase 1A Isoforms in Liver, Intestine, and Kidney Using Nanobore Liquid Chromatography–Tandem Mass Spectrometry

(2011) David E. Harbourt et al.   ANALYTICAL CHEMISTRY

Fatty acid transport proteins, implications in physiology and disease

(2011) Melissa Kazantzis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

(2011) V. Gorboulev et al.   DIABETES

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Quantitative Targeted Absolute Proteomics-Based Adme Research as A New Path to Drug Discovery and Development: Methodology, Advantages, Strategy, and Prospects

(2011) Sumio Ohtsuki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma

(2011) Sheng-Hua Chu et al.   Journal of Translational Medicine

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

(2011) Ramzi Shawahna et al.   MOLECULAR PHARMACEUTICS

FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase

(2010) Alaric Falcon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Role of Human Liver Microsomes in In Vitro Metabolism of Drugs—A Review

(2009) Sepuri Asha et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

(2008) S. Ohno et al.   DRUG METABOLISM AND DISPOSITION

Phase Transfer Surfactant-Aided Trypsin Digestion for Membrane Proteome Analysis

(2008) Takeshi Masuda et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

(2008) Junichi Kamiie et al.   PHARMACEUTICAL RESEARCH