Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease

B Cell Antigen Presentation Is Sufficient To Drive Neuroinflammation in an Animal Model of Multiple Sclerosis

(2015) Chelsea R. Parker Harp et al.   JOURNAL OF IMMUNOLOGY

B10 Cells: A Functionally Defined Regulatory B Cell Subset

(2015) Thomas F. Tedder   JOURNAL OF IMMUNOLOGY

Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity

(2015) Yaron Carmi et al.   NATURE

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses

(2014) Nils Schweingruber et al.   ACTA NEUROPATHOLOGICA

Immunology of Relapse and Remission in Multiple Sclerosis

(2014) Lawrence Steinman   Annual Review of Immunology

Peripheral T Cells Are the Therapeutic Targets of Glucocorticoids in Experimental Autoimmune Encephalomyelitis

(2014) S. Wust et al.   JOURNAL OF IMMUNOLOGY

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes

(2014) Menna R Clatworthy et al.   NATURE MEDICINE

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

(2013) Nicolas Molnarfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator

(2013) Marsilius Mues et al.   NATURE MEDICINE

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

(2013) Dmitri Lodygin et al.   NATURE MEDICINE

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B cells and antibodies in multiple sclerosis pathogenesis and therapy

(2012) Markus Krumbholz et al.   Nature Reviews Neurology

Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders

(2011) Simone Mader et al.   Journal of Neuroinflammation

CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS

(2010) Tommy Regen et al.   BRAIN BEHAVIOR AND IMMUNITY

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

(2009) Chih-Chi Andrew Hu et al.   EMBO JOURNAL

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Localizing central nervous system immune surveillance: Meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

(2008) Pia Kivisäkk et al.   ANNALS OF NEUROLOGY

Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis

(2008) Birgit Obermeier et al.   NATURE MEDICINE

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis

(2008) C. Hetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA