Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses

Peripheral T Cells Are the Therapeutic Targets of Glucocorticoids in Experimental Autoimmune Encephalomyelitis

(2014) S. Wust et al.   JOURNAL OF IMMUNOLOGY

Physiology and Pharmacology of Plerixafor

(2013) Simon P. Fricker   TRANSFUSION MEDICINE AND HEMOTHERAPY

The Ambivalent Role of Apoptosis in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

(2012) Holger M. Reichardt et al.   CURRENT PHARMACEUTICAL DESIGN

Glucocorticoids Enhance Intestinal Glucose Uptake Via the Dimerized Glucocorticoid Receptor in Enterocytes

(2012) Sybille D. Reichardt et al.   ENDOCRINOLOGY

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity

(2011) Lillian Cruz-Orengo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T Cell Development Critically Depends on Prethymic Stromal Patched Expression

(2011) A. Uhmann et al.   JOURNAL OF IMMUNOLOGY

Acid Sphingomyelinase Is Required for Protection of Effector Memory T Cells against Glucocorticoid-Induced Cell Death

(2011) D. Tischner et al.   JOURNAL OF IMMUNOLOGY

Liposomal Encapsulation of Glucocorticoids Alters Their Mode of Action in the Treatment of Experimental Autoimmune Encephalomyelitis

(2011) Nils Schweingruber et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of Glucocorticoids in the Control of Neuroinflammation

(2011) N. Schweingruber et al.   JOURNAL OF NEUROENDOCRINOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells

(2011) U. Baschant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The blood–brain barrier, chemokines and multiple sclerosis

(2010) David W. Holman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

The role of the glucocorticoid receptor in inflammation and immunity

(2010) Ulrike Baschant et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization

(2009) Volker Siffrin et al.   BRAIN

Stable silencing of the glucocorticoid receptor in myelin-specific T effector cells by retroviral delivery of shRNA: Insight into neuroinflammatory disease

(2009) Denise Tischner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cxcl10 enhances blood cells migration in the sub-ventricular zone of mice affected by experimental autoimmune encephalomyelitis

(2009) Luca Muzio et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis

(2009) Simone Wüst et al.   PLoS One

Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck

(2008) M. C. Ghosh et al.   BLOOD

Glucocorticoids induce an activated, anti-inflammatory monocyte subset in mice that resembles myeloid-derived suppressor cells

(2008) Georg Varga et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice

(2008) Adriana C Dos Santos et al.   Journal of Neuroinflammation