Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide

Galanin (1–15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system

(2016) Carmelo Millón et al.   Brain Structure & Function

Expression of galanin and its receptors are perturbed in a rodent model of mild, blast-induced traumatic brain injury

(2016) Lizan Kawa et al.   EXPERIMENTAL NEUROLOGY

Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

(2016) Aysu Okbay et al.   NATURE GENETICS

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

Chronic venlafaxine treatment fails to alter the levels of galanin system transcripts in normal rats

(2016) Peter Petschner et al.   NEUROPEPTIDES

Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray

(2016) Peng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depressive vulnerability, stressful life events and episode onset of major depression: a longitudinal model

(2016) K. S. Kendler et al.   PSYCHOLOGICAL MEDICINE

Epigenetic inactivation of galanin and GALR1/2 is associated with early recurrence in head and neck cancer

(2015) Kiyoshi Misawa et al.   CLINICAL & EXPERIMENTAL METASTASIS

Developments in the field of antidepressants, where do we go now?

(2015) Francesc Artigas   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Learning from the past and looking to the future: Emerging perspectives for improving the treatment of psychiatric disorders

(2015) Mark J. Millan et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A Role for Galanin N-Terminal Fragment (1–15) in Anxiety- and Depression-Related Behaviors in Rats

(2015) Carmelo Millón et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Effects of Postmortem Interval on Biomolecule Integrity in the Brain

(2015) Corina Nagy et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine

(2015) Nils C. Gassen et al.   Science Signaling

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine

(2015) Nils C. Gassen et al.   Science Signaling

Increased neurokinin-1 receptor availability in the amygdala in social anxiety disorder: a positron emission tomography study with [11C]GR205171

(2015) A Frick et al.   Translational Psychiatry

Influence of COMT Genotype on Antero-posterior Cortical Functional Connectivity Underlying Interference Resolution

(2014) Mathieu Jaspar et al.   CEREBRAL CORTEX

Conserved transcription factor binding sites suggest an activator basal promoter and a distal inhibitor in the galanin gene promoter in mouse ES cells

(2014) Sayonara Gonzalez et al.   GENE

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

(2014) D. Kohno et al.   JOURNAL OF NEUROSCIENCE

GAL3 receptor KO mice exhibit an anxiety-like phenotype

(2014) S. M. Brunner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain galanin system genes interact with life stresses in depression-related phenotypes

(2014) G. Juhasz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Methylation Changes in the Brains of Suicide Completers

(2013) Benoit Labonté et al.   AMERICAN JOURNAL OF PSYCHIATRY

Development of a High-Throughput Screening–Compatible Cell-Based Functional Assay to Identify Small Molecule Probes of the Galanin 3 Receptor (GalR3)

(2013) James Robinson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Tumor suppressor activity and inactivation of galanin receptor type 2 by aberrant promoter methylation in head and neck cancer

(2013) Yuki Misawa et al.   CANCER

GALR1 Methylation in Vaginal Swabs Is Highly Accurate in Identifying Women With Endometrial Cancer

(2013) Konstantinos Doufekas et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies

(2013) Emiliangelo Ratti et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe

(2013) E. Le Maitre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels

(2012) Nicole Zimmermann et al.   BIOCHEMICAL JOURNAL

Evolution of Galanin Receptor Genes: Insights from the Deuterostome Genomes

(2012) Zhenhui Liu et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

A mega-analysis of genome-wide association studies for major depressive disorder

(2012)   MOLECULAR PSYCHIATRY

Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?

(2012) Guy Griebel et al.   NATURE REVIEWS DRUG DISCOVERY

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic Mechanisms of Depression and Antidepressant Action

(2011) Vincent Vialou et al.   Annual Review of Pharmacology and Toxicology

The size and burden of mental disorders and other disorders of the brain in Europe 2010

(2011) H.U. Wittchen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Epigenetic Regulation of Glucose Transporter 4 by Estrogen Receptor β

(2011) Joëlle Rüegg et al.   MOLECULAR ENDOCRINOLOGY

Balancing histone methylation activities in psychiatric disorders

(2011) Cyril Jayakumar Peter et al.   TRENDS IN MOLECULAR MEDICINE

Chemical neuroanatomy of the dorsal raphe nucleus and adjacent structures of the mouse brain

(2010) Wenyu Fu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Genome-wide association study of major depressive disorder: new results, meta-analysis and lessons learned

(2010) N R Wray et al.   MOLECULAR PSYCHIATRY

Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response

(2010) Diego A Pizzagalli   NEUROPSYCHOPHARMACOLOGY

Neuropeptides from concept to online database www.neuropeptides.nl

(2009) J. Peter H. Burbach   EUROPEAN JOURNAL OF PHARMACOLOGY

Dendritic synthesis and release of the neuropeptide galanin: Morphological evidence from studies on rat locus coeruleus neurons

(2009) Évelyne Vila-Porcile et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice

(2009) Xiaoying Lu et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression

(2008) Wayne C. Drevets et al.   Brain Structure & Function

Epigenetic Inactivation of Galanin Receptor 1 in Head and Neck Cancer

(2008) K. Misawa et al.   CLINICAL CANCER RESEARCH

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord

(2008) Dominique Bröhl et al.   DEVELOPMENTAL BIOLOGY

Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators

(2008) Bruce S. McEwen   EUROPEAN JOURNAL OF PHARMACOLOGY

Cytology and receptor architecture of human anterior cingulate cortex

(2008) Nicola Palomero-Gallagher et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The effects of pH on DNA methylation state: In vitro and post-mortem brain studies

(2008) Carl Ernst et al.   JOURNAL OF NEUROSCIENCE METHODS

Polymorphisms in the galanin gene are associated with symptom–severity in female patients suffering from panic disorder

(2007) Paul G. Unschuld et al.   JOURNAL OF AFFECTIVE DISORDERS