Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition

IKrImpact on Repolarization and Its Variability Assessed by Dynamic Clamp

(2015) Claudia Altomare et al.   Circulation-Arrhythmia and Electrophysiology

Application of stochastic phenomenological modelling to cell-to-cell and beat-to-beat electrophysiological variability in cardiac tissue

(2015) John Walmsley et al.   JOURNAL OF THEORETICAL BIOLOGY

Role of Gap Junction Channel in the Development of Beat-to-Beat Action Potential Repolarization Variability and Arrhythmias

(2015) Janos Magyar et al.   CURRENT PHARMACEUTICAL DESIGN

Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes

(2014) Norbert Szentandrássy et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Inter-Subject Variability in Human Atrial Action Potential in Sinus Rhythm versus Chronic Atrial Fibrillation

(2014) Carlos Sánchez et al.   PLoS One

Single-channel basis for the slow activation of the repolarizing cardiac potassium current,IKs

(2013) Daniel Werry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diastolic Spontaneous Calcium Release From the Sarcoplasmic Reticulum Increases Beat-to-Beat Variability of Repolarization in Canine Ventricular Myocytes After β-Adrenergic Stimulation

(2012) Daniel M. Johnson et al.   CIRCULATION RESEARCH

Beat-to-beat variability of repolarization as a new biomarker for proarrhythmia in vivo

(2012) Rosanne Varkevisser et al.   HEART RHYTHM

An in silico canine cardiac midmyocardial action potential duration model as a tool for early drug safety assessment

(2011) M. R. Davies et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A Multiscale Investigation of Repolarization Variability and Its Role in Cardiac Arrhythmogenesis

(2011) Esther Pueyo et al.   BIOPHYSICAL JOURNAL

Effects of rosiglitazone on the configuration of action potentials and ion currents in canine ventricular cells

(2011) N Szentandrássy et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardiac ventricular repolarization reserve: a principle for understanding drug-related proarrhythmic risk

(2011) András Varró et al.   BRITISH JOURNAL OF PHARMACOLOGY

Late Sodium Current Contributes to the Reverse Rate-Dependent Effect of I Kr Inhibition on Ventricular Repolarization

(2011) Lin Wu et al.   CIRCULATION

Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: A computational analysis

(2011) Amrita X. Sarkar et al.   HEART RHYTHM

Effects of stochastic channel gating and distribution on the cardiac action potential

(2011) Mathieu Lemay et al.   JOURNAL OF THEORETICAL BIOLOGY

Usefulness of Short-Term Variability of QT Intervals as a Predictor for Electrical Remodeling and Proarrhythmia in Patients With Nonischemic Heart Failure

(2010) Martin Hinterseer et al.   AMERICAN JOURNAL OF CARDIOLOGY

Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium

(2009) Keith F. Decker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential

(2009) Najah Abi-Gerges et al.   BRITISH JOURNAL OF PHARMACOLOGY