Late Sodium Current Contributes to the Reverse Rate-Dependent Effect of I Kr Inhibition on Ventricular Repolarization

Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na+ current in the heart

(2009) Lin Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Self-augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency

(2009) László Virág et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reverse rate dependency is an intrinsic property of canine cardiac preparations

(2009) Tamás Bányász et al.   CARDIOVASCULAR RESEARCH

Milrinone inhibits hypoxia or hydrogen dioxide-induced persistent sodium current in ventricular myocytes

(2009) Jie Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

IKs restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation

(2009) Daniel M. Johnson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Control of the cardiac action potential: The role of repolarization dynamics

(2009) Antonio Zaza   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A novel computational model of the human ventricular action potential and Ca transient

(2009) Eleonora Grandi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Use and abuse of QT and TRIaD in cardiac safety research: Importance of study design and conduct

(2008) Luc M. Hondeghem   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine

(2008) Lin Wu et al.   HEART RHYTHM

Role of activated CaMKII in abnormal calcium homeostasis and INa remodeling after myocardial infarction: Insights from mathematical modeling

(2008) Thomas J. Hund et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pathophysiology and pharmacology of the cardiac “late sodium current”

(2008) Antonio Zaza et al.   PHARMACOLOGY & THERAPEUTICS

State dependent dissociation of HERG channel inhibitors

(2007) D Stork et al.   BRITISH JOURNAL OF PHARMACOLOGY