Friend, foe or food? Recognition and the role of antimicrobial peptides in gut immunity andDrosophila–microbe interactions

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

Sensing Gram-negative bacteria: a phylogenetic perspective

(2016) Claudine Neyen et al.   CURRENT OPINION IN IMMUNOLOGY

Understanding regulation of the host-mediated gut symbiont population and the symbiont-mediated host immunity in the Riptortus-Burkholderia symbiosis system

(2016) Jiyeun Kate Kim et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Towards a paradigm shift in innate immunity—seminal work by Hans G. Boman and co-workers

(2016) Ingrid Faye et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Antimicrobial effectors in the nematodeCaenorhabditis elegans: an outgroup to the Arthropoda

(2016) Katja Dierking et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Consumption of dietary sugar by gut bacteria determinesDrosophilalipid content

(2015) Jia-Hsin Huang et al.   Biology Letters

Pathogen Virulence Impedes Mutualist-Mediated Enhancement of Host Juvenile Growth via Inhibition of Protein Digestion

(2015) Berra Erkosar et al.   Cell Host & Microbe

Intestinal FoxO signaling is required to survive oral infection in Drosophila

(2015) C Fink et al.   Mucosal Immunology

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

Microbes Promote Amino Acid Harvest to Rescue Undernutrition in Drosophila

(2015) Ryuichi Yamada et al.   Cell Reports

The secret lives of Drosophila flies

(2015) Therese Ann Markow   eLife

A Common Origin for Immunity and Digestion

(2015) Nichole A. Broderick   Frontiers in Immunology

Age-Associated Loss of Lamin-B Leads to Systemic Inflammation and Gut Hyperplasia

(2014) Haiyang Chen et al.   CELL

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

(2014) Linlin Guo et al.   CELL

Insects Recycle Endosymbionts when the Benefit Is Over

(2014) Aurélien Vigneron et al.   CURRENT BIOLOGY

Transient adult microbiota, gut homeostasis and longevity: Novel insights from the Drosophila model

(2014) Berra Erkosar et al.   FEBS LETTERS

What Is a Host? Incorporating the Microbiota into the Damage-Response Framework: TABLE 1

(2014) Arturo Casadevall et al.   INFECTION AND IMMUNITY

A Deregulated Intestinal Cell Cycle Program Disrupts Tissue Homeostasis without Affecting Longevity in Drosophila

(2014) Kristina Petkau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Social attraction mediated by fruit flies' microbiome

(2014) I. Venu et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Gut microbiota dictates the metabolic response of Drosophila to diet

(2014) A. C.- N. Wong et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Pirk Is a Negative Regulator of the Drosophila Imd Pathway

(2014) A. Kleino et al.   JOURNAL OF IMMUNOLOGY

The Drosophila Imd Signaling Pathway

(2014) H. Myllymaki et al.   JOURNAL OF IMMUNOLOGY

Drosophila Microbiota Modulates Host Metabolic Gene Expression via IMD/NF-κB Signaling

(2014) Berra Erkosar Combe et al.   PLoS One

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

(2014) N. A. Broderick et al.   mBio

Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

(2014) Amandine Everard et al.   Nature Communications

Transforming Growth Factor β/Activin Signaling Functions as a Sugar-Sensing Feedback Loop to Regulate Digestive Enzyme Expression

(2014) Wen-bin Alfred Chng et al.   Cell Reports

How Microbiomes Influence Metazoan Development:Insights from History andDrosophilaModeling of Gut-Microbe Interactions

(2013) Won-Jae Lee et al.   Annual Review of Cell and Developmental Biology

The Digestive Tract ofDrosophila melanogaster

(2013) Bruno Lemaitre et al.   Annual Review of Genetics

Interspecies Interactions Determine the Impact of the Gut Microbiota on Nutrient Allocation in Drosophila melanogaster

(2013) Peter D. Newell et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

MEF2 Is an In Vivo Immune-Metabolic Switch

(2013) Rebecca I. Clark et al.   CELL

Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila

(2013) Kyung-Ah Lee et al.   CELL

The inconstant gut microbiota of Drosophila species revealed by 16S rRNA gene analysis

(2013) Adam C-N Wong et al.   ISME Journal

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Gut homeostasis in a microbial world: insights from Drosophila melanogaster

(2013) Nicolas Buchon et al.   NATURE REVIEWS MICROBIOLOGY

Host Species and Environmental Effects on Bacterial Communities Associated with Drosophila in the Laboratory and in the Natural Environment

(2013) Fabian Staubach et al.   PLoS One

Animals in a bacterial world, a new imperative for the life sciences

(2013) Margaret McFall-Ngai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent Replenishment Sustains the Beneficial Microbiome of Drosophila melanogaster

(2013) J. E. Blum et al.   mBio

Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila

(2013) Nicolas Buchon et al.   Cell Reports

Physiological and stem cell compartmentalization within the Drosophila midgut

(2013) Alexis Marianes et al.   eLife

Host-microbe interactions in the gut of Drosophila melanogaster

(2013) Takayuki Kuraishi et al.   Frontiers in Physiology

Yeast Communities of Diverse Drosophila Species: Comparison of Two Symbiont Groups in the Same Hosts

(2012) James Angus Chandler et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Infection-Induced Host Translational Blockage Inhibits Immune Responses and Epithelial Renewal in the Drosophila Gut

(2012) Sveta Chakrabarti et al.   Cell Host & Microbe

Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota

(2012) Virginie Bosco-Drayon et al.   Cell Host & Microbe

A negative role for MyD88 in the resistance to starvation as revealed in an intestinal infection of Drosophila melanogaster with the Gram-positive bacterium Staphylococcus xylosus

(2012) Arshad Ayyaz et al.   IMMUNOBIOLOGY

Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE

(2012) C. Neyen et al.   JOURNAL OF IMMUNOLOGY

New Insights into the Ecological Interaction Between Grape Berry Microorganisms and Drosophila Flies During the Development of Sour Rot

(2012) André Barata et al.   MICROBIAL ECOLOGY

Activating Transcription Factor 3 Regulates Immune and Metabolic Homeostasis

(2012) J. Rynes et al.   MOLECULAR AND CELLULAR BIOLOGY

Knowing your friends: invertebrate innate immunity fosters beneficial bacterial symbioses

(2012) Spencer V. Nyholm et al.   NATURE REVIEWS MICROBIOLOGY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Impact of the Resident Microbiota on the Nutritional Phenotype of Drosophila melanogaster

(2012) Emma V. Ridley et al.   PLoS One

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut-microbiota interactions in non-mammals: What can we learn from Drosophila?

(2012) Bernard Charroux et al.   SEMINARS IN IMMUNOLOGY

Ecological Physiology of Diet and Digestive Systems

(2011) William H. Karasov et al.   Annual Review of Physiology

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

(2011) Nicolas Buchon et al.   BMC BIOLOGY

Lessons from Studying Insect Symbioses

(2011) Angela E. Douglas   Cell Host & Microbe

Lactobacillus plantarum Promotes Drosophila Systemic Growth by Modulating Hormonal Signals through TOR-Dependent Nutrient Sensing

(2011) Gilles Storelli et al.   Cell Metabolism

Maintaining Tissue Homeostasis: Dynamic Control of Somatic Stem Cell Activity

(2011) Benoit Biteau et al.   Cell Stem Cell

Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans

(2011) M. T. Glittenberg et al.   Disease Models & Mechanisms

Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection

(2011) Juan C. Paredes et al.   IMMUNITY

Attraction of Drosophila melanogaster males to food-related and fly odours

(2011) Sébastien Lebreton et al.   JOURNAL OF INSECT PHYSIOLOGY

Drosophila – a versatile model in biology & medicine

(2011) Barbara H. Jennings   Materials Today

Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster

(2011) T. Kuraishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatially selective colonization of the arthropod intestine through activation of Vibrio cholerae biofilm formation

(2011) A. E. Purdy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila Microbiome Modulates Host Developmental and Metabolic Homeostasis via Insulin Signaling

(2011) S. C. Shin et al.   SCIENCE

From Commensal to Pathogen: Translocation of Enterococcus faecalis from the Midgut to the Hemocoel of Manduca sexta

(2011) K. L. Mason et al.   mBio

Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System

(2011) James Angus Chandler et al.   PLoS Genetics

A new vision of immunity: homeostasis of the superorganism

(2010) G Eberl   Mucosal Immunology

FOXO-dependent regulation of innate immune homeostasis

(2010) Thomas Becker et al.   NATURE

Commensal bacteria play a role in mating preference of Drosophila melanogaster

(2010) G. Sharon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Drosophila Intestinal Response to Bacterial Infection: Activation of Host Defense and Stem Cell Proliferation

(2009) Nicolas Buchon et al.   Cell Host & Microbe

Tissue Damage-Induced Intestinal Stem Cell Division in Drosophila

(2009) Alla Amcheslavsky et al.   Cell Stem Cell

Regulation of DUOX by the Gαq-Phospholipase Cβ-Ca2+ Pathway in Drosophila Gut Immunity

(2009) Eun-Mi Ha et al.   DEVELOPMENTAL CELL

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

Pathogenic stimulation of intestinal stem cell response in drosophila

(2009) Madhurima Chatterjee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The gut microbiota modulates host energy and lipid metabolism in mice

(2009) Vidya R. Velagapudi et al.   JOURNAL OF LIPID RESEARCH

Coordination of multiple dual oxidase–regulatory pathways in responses to commensal and infectious microbes in drosophila gut

(2009) Eun-Mi Ha et al.   NATURE IMMUNOLOGY

PIMS Modulates Immune Tolerance by Negatively Regulating Drosophila Innate Immune Signaling

(2008) Nouara Lhocine et al.   Cell Host & Microbe

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Feeding Our Immune System: Impact on Metabolism

(2008) Isabelle Wolowczuk et al.   Clinical & Developmental Immunology

Bacterial strategies to overcome insect defences

(2008) Isabelle Vallet-Gely et al.   NATURE REVIEWS MICROBIOLOGY

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

(2008) J.-H. Ryu et al.   SCIENCE