Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors

Variability in bioavailability of small molecular tyrosine kinase inhibitors

(2015) Maikel Herbrink et al.   CANCER TREATMENT REVIEWS

Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma

(2014) Cristina Tintori et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 1-Methyl-1H-imidazole Derivatives as Potent Jak2 Inhibitors

(2013) Qibin Su et al.   JOURNAL OF MEDICINAL CHEMISTRY

Locking the Active Conformation of c-Src Kinase through the Phosphorylation of the Activation Loop

(2013) Yilin Meng et al.   JOURNAL OF MOLECULAR BIOLOGY

Development of a Highly Selective c-Src Kinase Inhibitor

(2012) Kristoffer R. Brandvold et al.   ACS Chemical Biology

An update on dual Src/Abl inhibitors

(2012) Francesca Musumeci et al.   Future Medicinal Chemistry

Comprehensive analysis of kinase inhibitor selectivity

(2011) Mindy I Davis et al.   NATURE BIOTECHNOLOGY

Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells

(2010) Michele Navarra et al.   BMC CANCER

Protein Kinases: Docking and Homology Modeling Reliability

(2010) Tiziano Tuccinardi et al.   Journal of Chemical Information and Modeling

Computational studies of the interaction between the HIV-1 integrase tetramer and the cofactor LEDGF/p75: Insights from molecular dynamics simulations and the Informational spectrum method

(2010) Cristina Tintori et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

Homology modeling in drug discovery: current trends and applications

(2009) Claudio N. Cavasotto et al.   DRUG DISCOVERY TODAY

Hybrid Compound Design To Overcome the Gatekeeper T338M Mutation in cSrc#

(2009) Matthäus Getlik et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal Structures of the Lyn Protein Tyrosine Kinase Domain in Its Apo- and Inhibitor-bound State

(2008) Neal K. Williams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia

(2008) Shaoguang Li   LEUKEMIA & LYMPHOMA