Is Modulation of Oxidative Stress an Answer? The State of the Art of Redox Therapeutic Actions in Neurodegenerative Diseases

Regulation of Copper and Iron Homeostasis by Metal Chelators: A Possible Chemotherapy for Alzheimer’s Disease

(2015) Anne Robert et al.   ACCOUNTS OF CHEMICAL RESEARCH

Oxidative Stress in Alzheimer’s Disease: Should We Keep Trying Antioxidant Therapies?

(2015) Michelli Erica Souza Ferreira et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Glutathione redox imbalance in brain disorders

(2015) Feng Gu et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Melatonin Redox Activity. Its Potential Clinical Applications in Neurodegenerative Disorders

(2015) Elzbieta Miller et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The Effect of Creatine and Coenzyme Q10 Combination Therapy on Mild Cognitive Impairment in Parkinson's Disease

(2015) Zhenguang Li et al.   EUROPEAN NEUROLOGY

Dimethyl Fumarate Protects Neural Stem/Progenitor Cells and Neurons from Oxidative Damage through Nrf2-ERK1/2 MAPK Pathway

(2015) Qin Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Insights on the interaction of alpha-synuclein and metals in the pathophysiology of Parkinson's disease

(2015) Eleonora Carboni et al.   Metallomics

A randomized, double-blind phase I/IIa study of intranasal glutathione in Parkinson's disease

(2015) Laurie K. Mischley et al.   MOVEMENT DISORDERS

Oxidative stress and Parkinson’s disease

(2015) Javier Blesa et al.   Frontiers in Neuroanatomy

The Effectiveness of Dimethyl Fumarate Monotherapy in the Treatment of Relapsing-Remitting Multiple Sclerosis: A Systematic Review and Meta-Analysis

(2014) Pawel Kawalec et al.   Current Neuropharmacology

Novel Targets in Multiple Sclerosis: To Oxidative Stress and Beyond

(2014) Valerio Chiurchiu   CURRENT TOPICS IN MEDICINAL CHEMISTRY

ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress

(2014) Jesse R. McLean et al.   EXPERIMENTAL NEUROLOGY

Hereditary spastic paraplegia: Clinical-genetic characteristics and evolving molecular mechanisms

(2014) Temistocle Lo Giudice et al.   EXPERIMENTAL NEUROLOGY

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

(2014) Rajkumar Noubade et al.   NATURE

The phenotypic variability of amyotrophic lateral sclerosis

(2014) Bart Swinnen et al.   Nature Reviews Neurology

The emerging role of nutrition in Parkinson's disease

(2014) Stacey E. Seidl et al.   Frontiers in Aging Neuroscience

Pharmacology and clinical efficacy of dimethyl fumarate (BG-12) for treatment of relapsing–remitting multiple sclerosis

(2014) Claudio Gasperini et al.   Therapeutics and Clinical Risk Management

Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms

(2013) John K. Fink   ACTA NEUROPATHOLOGICA

The role of oxidative stress during inflammatory processes

(2013) Jérôme Lugrin et al.   BIOLOGICAL CHEMISTRY

Which Immune Cells Matter? The Immunopathogenesis of Multiple Sclerosis

(2013) Bieke Broux et al.   CRITICAL REVIEWS IN IMMUNOLOGY

BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety

(2013) Robert J. Fox et al.   CURRENT MEDICAL RESEARCH AND OPINION

Reactive Oxygen Species in the Immune System

(2013) Yuhui Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Uptake of environmental toxicants by the locus ceruleus: A potential trigger for neurodegenerative, demyelinating and psychiatric disorders

(2013) Roger Pamphlett   MEDICAL HYPOTHESES

Efficacy of Fish Oil on Serum of TNFα, IL-1β, and IL-6 Oxidative Stress Markers in Multiple Sclerosis Treated with Interferon Beta-1b

(2013) V. Ramirez-Ramirez et al.   Oxidative Medicine and Cellular Longevity

BG-12 in Multiple Sclerosis

(2013) Robert Fox et al.   SEMINARS IN NEUROLOGY

Alteration of Fatty-Acid-Metabolizing Enzymes Affects Mitochondrial Form and Function in Hereditary Spastic Paraplegia

(2012) Christelle Tesson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cellular Pathways of Hereditary Spastic Paraplegia

(2012) Craig Blackstone   Annual Review of Neuroscience

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

The influence of nutritional factors on the prognosis of multiple sclerosis

(2012) Gloria von Geldern et al.   Nature Reviews Neurology

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis

(2012) Robert J. Fox et al.   NEW ENGLAND JOURNAL OF MEDICINE

Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

(2012) Ralf Gold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular and molecular mechanisms of antioxidants in Parkinson's disease

(2012) Jhon Jairo Sutachan et al.   NUTRITIONAL NEUROSCIENCE

Chronic Inflammatory Disorders and Their Redox Control: From Molecular Mechanisms to Therapeutic Opportunities

(2011) Valerio Chiurchiù et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Stress and Blood–Brain Barrier Dysfunction Under Particular Consideration of Matrix Metalloproteinases

(2011) Christine Lehner et al.   ANTIOXIDANTS & REDOX SIGNALING

Alzheimer's Disease: Redox Dysregulation As a Common Denominator for Diverse Pathogenic Mechanisms

(2011) Rommy von Bernhardi et al.   ANTIOXIDANTS & REDOX SIGNALING

The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis

(2011) James Leiper et al.   NATURE REVIEWS DRUG DISCOVERY

Clioquinol: Review of its Mechanisms of Action and Clinical Uses in Neurodegenerative Disorders

(2010) Silvio R. Bareggi et al.   CNS Neuroscience & Therapeutics

Immune-Inflammatory Responses and Oxidative Stress in Alzheimers Disease: Therapeutic Implications

(2010) D. Bona et al.   CURRENT PHARMACEUTICAL DESIGN

Antioxidant approaches for the treatment of Alzheimer’s disease

(2010) Hyun Pil Lee et al.   Expert Review of Neurotherapeutics

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Redox Modifier Genes and Pathways in Amyotrophic Lateral Sclerosis

(2009) Barrie J. Carter et al.   ANTIOXIDANTS & REDOX SIGNALING

Is oxidative damage in operation in patients with hereditary spastic paraparesis?

(2009) Kıvılcım Gücüyener et al.   BRAIN & DEVELOPMENT

Targeting the Progression of Parkinsons Disease

(2009) J. George et al.   Current Neuropharmacology

Combination therapy with Coenzyme Q10and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases

(2009) Lichuan Yang et al.   JOURNAL OF NEUROCHEMISTRY

Role of the innate immune system in the pathogenesis of multiple sclerosis

(2009) Roopali Gandhi et al.   JOURNAL OF NEUROIMMUNOLOGY

Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin

(2009) Genny Orso et al.   NATURE

Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis,

(2009) L. Shinto et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the Treatment of Amyotrophic Lateral Sclerosis

(2008) Valentin K. Gribkoff et al.   CNS Neuroscience & Therapeutics

Xanthine oxidase-dependent ROS production mediates vitamin A pro-oxidant effects in cultured Sertoli cells

(2008) Alfeu Zanotto-Filho et al.   FREE RADICAL RESEARCH

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

(2008) Maged M. Harraz et al.   JOURNAL OF CLINICAL INVESTIGATION

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13)

(2008) J. Hansen et al.   NEUROSCIENCE

Therapeutics for Alzheimer’s disease based on the metal hypothesis

(2008) Ashley I. Bush et al.   Neurotherapeutics