The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis
出版年份 2011 全文链接
标题
The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume 10, Issue 4, Pages 277-291
出版商
Springer Nature
发表日期
2011-04-01
DOI
10.1038/nrd3358
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1
- (2010) Matthew Lluis et al. ChemMedChem
- A Novel Loss-of-Function DDAH1 Promoter Polymorphism Is Associated With Increased Susceptibility to Thrombosis Stroke and Coronary Heart Disease
- (2010) Hu Ding et al. CIRCULATION RESEARCH
- Vascular hyporesponsiveness to vasopressors in septic shock: from bench to bedside
- (2010) B. Levy et al. INTENSIVE CARE MEDICINE
- Improvement of endothelial dysfunction in atherosclerotic rabbit aortas by ex vivo gene transferring of dimethylarginine dimethylaminohydrolase-2
- (2010) Mei Feng et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Modulating the NO generating system from a medicinal chemistry perspective: Current trends and therapeutic options in cardiovascular disease
- (2010) Dennis Schade et al. PHARMACOLOGY & THERAPEUTICS
- Sequence Variation in DDAH1 and DDAH2 Genes Is Strongly and Additively Associated with Serum ADMA Concentrations in Individuals with Type 2 Diabetes
- (2010) Sotoodeh Abhary et al. PLoS One
- EFFECTS OF A SELECTIVE iNOS INHIBITOR VERSUS NOREPINEPHRINE IN THE TREATMENT OF SEPTIC SHOCK
- (2010) Fuhong Su et al. SHOCK
- Adenoviral-mediated overexpression of DDAH improves vascular tone regulation
- (2010) Belen Torondel et al. VASCULAR MEDICINE
- Ex vivo gene transferring of human dimethylarginine dimethylaminohydrolase-2 improved endothelial dysfunction in diabetic rat aortas and high glucose-treated endothelial cells
- (2009) Chang-Wu Lu et al. ATHEROSCLEROSIS
- Developing Dual and Specific Inhibitors of Dimethylarginine Dimethylaminohydrolase-1 and Nitric Oxide Synthase: Toward a Targeted Polypharmacology To Control Nitric Oxide
- (2009) Yun Wang et al. BIOCHEMISTRY
- Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death
- (2009) Gregory J. Kato et al. BRITISH JOURNAL OF HAEMATOLOGY
- Vascular Endothelial-Specific Dimethylarginine Dimethylaminohydrolase-1–Deficient Mice Reveal That Vascular Endothelium Plays an Important Role in Removing Asymmetric Dimethylarginine
- (2009) Xinli Hu et al. CIRCULATION
- Common genetic variation inDDAH2is associated with intracerebral haemorrhage in a Chinese population: a multi-centre case-control study in China
- (2009) Yongyi Bai et al. CLINICAL SCIENCE
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
- (2009) R Phillip Dellinger et al. CRITICAL CARE MEDICINE
- Asymmetrical Dimethylarginine Is Increased in Plasma and Decreased in Cerebrospinal Fluid of Patients with Alzheimer’s Disease
- (2009) Sönke Arlt et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease
- (2009) Carol Wadham et al. Expert Opinion on Drug Metabolism & Toxicology
- Role of Dimethylarginine Dimethylaminohydrolases in the Regulation of Endothelial Nitric Oxide Production
- (2009) Arthur J. Pope et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Alanine-Glyoxylate Aminotransferase 2 Lowers Asymmetric Dimethylarginine and Protects from Inhibition of Nitric Oxide Production
- (2009) Roman N. Rodionov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Circulating methylarginine levels and the decline in renal function in patients with chronic kidney disease are modulated by DDAH1 polymorphisms
- (2009) Ben Caplin et al. KIDNEY INTERNATIONAL
- Involvement of asymmetric dimethylarginine (ADMA) in glomerular capillary loss and sclerosis in a rat model of chronic kidney disease (CKD)
- (2009) Seiji Ueda et al. LIFE SCIENCES
- Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality—An update on patient populations with a wide range of cardiovascular risk
- (2009) Rainer H. Böger et al. PHARMACOLOGICAL RESEARCH
- From arginine methylation to ADMA: A novel mechanism with therapeutic potential in chronic lung diseases
- (2009) Dariusz Zakrzewicz et al. BMC Pulmonary Medicine
- Asymmetric Dimethylarginine and Lipid Peroxidation Products in Early Autosomal Dominant Polycystic Kidney Disease
- (2008) Dan Wang et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants
- (2008) Paul D. Speer et al. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Dimethylarginine Dimethylaminohydrolase Overexpression Enhances Insulin Sensitivity
- (2008) Karsten Sydow et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Structure–activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: Alkenyl-amidines as new leads
- (2008) Jürke Kotthaus et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Increased plasma asymmetric dimethylarginine (ADMA) levels in retinal venous occlusive disease
- (2008) Angelo Zinellu et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Relationship of asymmetric dimethylarginine with flow-mediated dilatation in subjects with newly detected severe hypercholesterolemia
- (2008) L. Vladimirova-Kitova et al. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
- Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine
- (2008) Mei Feng et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The Prominent Role of the Liver in the Elimination of Asymmetric Dimethylarginine (ADMA) and the Consequences of Impaired Hepatic Function
- (2008) Milan C. Richir et al. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
- ADMA Levels Correlate with Proteinuria, Secondary Amyloidosis, and Endothelial Dysfunction
- (2008) M. I. Yilmaz et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy
- (2008) R. Shibata et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Neuronal nitric oxide synthase expression in glial tumors: correlation with malignancy and tumor proliferation
- (2008) Necmettin Tanriover et al. NEUROLOGICAL RESEARCH
- The reemergence of nitric oxide and cancer
- (2008) David A. Wink et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- First-trimester uterine artery resistance and maternal serum concentration of asymmetric dimethylarginine
- (2008) F. Prefumo et al. ULTRASOUND IN OBSTETRICS & GYNECOLOGY
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