AnN-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species

Design, Synthesis, and Functional Evaluation of CO-Releasing Molecules Triggered by Penicillin G Amidase as a Model Protease

(2015) Nikolay S. Sitnikov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An artificial CO-releasing metalloprotein built by histidine-selective metallation

(2015) Inês S. Albuquerque et al.   CHEMICAL COMMUNICATIONS

A contribution to the rational design of Ru(CO)3Cl2L complexes for in vivo delivery of CO

(2015) João D. Seixas et al.   DALTON TRANSACTIONS

Spontaneous CO Release from RuII(CO)2-Protein Complexes in Aqueous Solution, Cells, and Mice

(2014) Miguel Chaves-Ferreira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Prodrug Platin-A: Simultaneous Release of Cisplatin and Aspirin

(2014) Rakesh K. Pathak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The ligation of aspirin to cisplatin demonstrates significant synergistic effects on tumor cells

(2014) Qinqin Cheng et al.   CHEMICAL COMMUNICATIONS

Syntheses and evaluation of drug-like properties of CO-releasing molecules containing ruthenium and group 6 metal

(2014) Pengpeng Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium(II) Thiol and H2S Complexes: Synthesis, Characterization, and Thermodynamic Properties

(2012) Erin S. F. Ma et al.   INORGANIC CHEMISTRY

New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme

(2012) M.F.A. Santos et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Thiol, Disulfide, and Trisulfide Complexes of Ru Porphyrins: Potential Models for Iron–Sulfur Bonds in Heme Proteins

(2012) Júlio S. Rebouças et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation

(2012) Brian W. Michel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

(2012) Ana R. Marques et al.   ORGANOMETALLICS

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

(2011) Ana C. Pena et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins

(2011) T. Santos-Silva et al.   CURRENT MEDICINAL CHEMISTRY

17 e−rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications

(2011) Ulrich Schatzschneider   INORGANICA CHIMICA ACTA

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex

(2011) Teresa Santos-Silva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart

(2010) Guangwu Wang et al.   CIRCULATION

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Carbon Monoxide Rescues Heme Oxygenase-1-Deficient Mice from Arterial Thrombosis in Allogeneic Aortic Transplantation

(2009) Bo Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

(2008) Seetal Dodd et al.   EXPERT OPINION ON BIOLOGICAL THERAPY