CSN6 controls the proliferation and metastasis of glioblastoma by CHIP-mediated degradation of EGFR

ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development

(2015) Lekun Fang et al.   CANCER CELL

Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma

(2015) D.-C. Lin et al.   CANCER RESEARCH

Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1

(2015) Fan Xuan et al.   NEURO-ONCOLOGY

COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer

(2015) Shujun Gao et al.   Oncotarget

MiR-1178 Promotes the Proliferation, G1/S Transition, Migration and Invasion of Pancreatic Cancer Cells by Targeting CHIP

(2015) Zhe Cao et al.   PLoS One

CHIP is a novel tumor suppressor in pancreatic cancer and inhibits tumor growth through targeting EGFR

(2015) Tianxiao Wang et al.   Oncotarget

CSN6 drives carcinogenesis by positively regulating Myc stability

(2014) Jian Chen et al.   Nature Communications

Using the molecular classification of glioblastoma to inform personalized treatment

(2013) Adriana Olar et al.   JOURNAL OF PATHOLOGY

The Ubiquitin Ligase CHIP Prevents SirT6 Degradation through Noncanonical Ubiquitination

(2013) Sarah M. Ronnebaum et al.   MOLECULAR AND CELLULAR BIOLOGY

The Chaperone-assisted E3 Ligase C Terminus of Hsc70-interacting Protein (CHIP) Targets PTEN for Proteasomal Degradation

(2012) Syed Feroj Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of COP9 signalosome in cancer

(2011) Mong-Hong Lee et al.   CELL CYCLE

Integration and analysis of genome-scale data from gliomas

(2011) Gregory Riddick et al.   Nature Reviews Neurology

A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

(2011) J. J. Raizer et al.   NEURO-ONCOLOGY

Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034

(2009) Martin J. van den Bent et al.   JOURNAL OF CLINICAL ONCOLOGY

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways

(2009) Masashi Kajiro et al.   NATURE CELL BIOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE