MiR-1178 Promotes the Proliferation, G1/S Transition, Migration and Invasion of Pancreatic Cancer Cells by Targeting CHIP

CHIP is a novel tumor suppressor in pancreatic cancer and inhibits tumor growth through targeting EGFR

(2015) Tianxiao Wang et al.   Oncotarget

C-terminus of Hsc70-interacting protein regulates profilin1 and breast cancer cell migration

(2014) Ye Na Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia?

(2014) A. M. Lennon et al.   CANCER RESEARCH

miR-211 Modulates Gemcitabine Activity Through Downregulation of Ribonucleotide Reductase and Inhibits the Invasive Behavior of Pancreatic Cancer Cells

(2014) Mina Maftouh et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

PI3K/Akt/mTOR pathway inhibitors in the therapy of pancreatic neuroendocrine tumors

(2013) Edward M. Wolin   CANCER LETTERS

miR-146b-5p inhibits glioma migration and invasion by targeting MMP16

(2013) Yanyan Li et al.   CANCER LETTERS

CHIP/Stub1 functions as a tumor suppressor and represses NF- B-mediated signaling in colorectal cancer

(2013) Y. Wang et al.   CARCINOGENESIS

MicroRNA-34b Inhibits Pancreatic Cancer Metastasis Through Repressing Smad3

(2013) C. Liu et al.   CURRENT MOLECULAR MEDICINE

Ca2+/S100 Proteins Act as Upstream Regulators of the Chaperone-associated Ubiquitin Ligase CHIP (C Terminus of Hsc70-interacting Protein)

(2013) Seiko Shimamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miRNA-141, Downregulated in Pancreatic Cancer, Inhibits Cell Proliferation and Invasion by Directly Targeting MAP4K4

(2013) Gang Zhao et al.   MOLECULAR CANCER THERAPEUTICS

Standing on the shoulders of mice, making an iMPACT on pancreatic cancer

(2013) M. Teresa Villanueva   Nature Reviews Clinical Oncology

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

(2013) Hui Ling et al.   NATURE REVIEWS DRUG DISCOVERY

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Src-mediated regulation of E-cadherin and EMT in pancreatic cancer

(2012) Nagaraj et al.   Frontiers in Bioscience-Landmark

miR-764-5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression

(2012) Junwei Guo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Abstract 5703: Up-regulation of miR-146a contributes to the inhibition of invasion of pancreatic cancer cells

(2011) Yiwei Li et al.   CANCER RESEARCH

Ubiquitin ligase CHIP induces TRAF2 proteasomal degradation and NF-κB inactivation to regulate breast cancer cell invasion

(2011) Kang Won Jang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The C-terminus of Hsp70-Interacting Protein Promotes Met Receptor Degradation

(2011) Kang Won Jang et al.   Journal of Thoracic Oncology

Functional Inactivation of Endogenous MDM2 and CHIP by HSP90 Causes Aberrant Stabilization of Mutant p53 in Human Cancer Cells

(2011) D. Li et al.   MOLECULAR CANCER RESEARCH

miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2

(2010) Yihui Ma et al.   CANCER LETTERS

Promotion of CHIP-Mediated p53 Degradation Protects the Heart From Ischemic Injury

(2010) Atsuhiko T. Naito et al.   CIRCULATION RESEARCH

CHIP-dependent p53 regulation occurs specifically during cellular senescence

(2010) Christina Sisoula et al.   FREE RADICAL BIOLOGY AND MEDICINE

CHIP Promotes Human Telomerase Reverse Transcriptase Degradation and Negatively Regulates Telomerase Activity

(2010) Ji Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP

(2010) Jia Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α

(2009) Weibo Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways

(2009) Masashi Kajiro et al.   NATURE CELL BIOLOGY

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS