SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial–mesenchymal transition and invasion in mice and humans
出版年份 2016 全文链接
标题
SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial–mesenchymal transition and invasion in mice and humans
作者
关键词
-
出版物
ONCOGENE
Volume 35, Issue 43, Pages 5641-5652
出版商
Springer Nature
发表日期
2016-04-04
DOI
10.1038/onc.2016.100
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- PDGFR and Play Critical Roles in Mediating Foxq1-Driven Breast Cancer Stemness and Chemoresistance
- (2014) F. Meng et al. CANCER RESEARCH
- EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis
- (2014) Haizhong Feng et al. JOURNAL OF CLINICAL INVESTIGATION
- The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer
- (2014) Peixin Dong et al. Journal of Translational Medicine
- Hypoxia-induced Bmi1 promotes renal tubular epithelial cell–mesenchymal transition and renal fibrosis via PI3K/Akt signal
- (2014) Rui Du et al. MOLECULAR BIOLOGY OF THE CELL
- CEACAM6 Promotes Gastric Cancer Invasion and Metastasis by Inducing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling Pathway
- (2014) Mingde Zang et al. PLoS One
- Signaling mechanisms of the epithelial-mesenchymal transition
- (2014) D. M. Gonzalez et al. Science Signaling
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
- (2013) Florian A. Siebzehnrubl et al. EMBO Molecular Medicine
- Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
- (2013) P. Mao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PI3K/Akt to GSK3β/β-catenin signaling cascade coordinates cell colonization for bladder cancer bone metastasis through regulating ZEB1 transcription
- (2012) Kaijie Wu et al. CELLULAR SIGNALLING
- Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis
- (2012) H. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Angiopoietin-2, an Angiogenic Regulator, Promotes Initial Growth and Survival of Breast Cancer Metastases to the Lung through the Integrin-linked Kinase (ILK)-AKT-B Cell Lymphoma 2 (Bcl-2) Pathway
- (2011) Yorihisa Imanishi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans
- (2011) Kun-Wei Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans
- (2011) Haizhong Feng et al. JOURNAL OF CLINICAL INVESTIGATION
- Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
- (2011) H Feng et al. ONCOGENE
- Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells
- (2011) Y Wang et al. ONCOGENE
- A Perspective on Cancer Cell Metastasis
- (2011) C. L. Chaffer et al. SCIENCE
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Automated Network Analysis Identifies Core Pathways in Glioblastoma
- (2010) Ethan Cerami et al. PLoS One
- E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
- (2009) Otto Schmalhofer et al. CANCER AND METASTASIS REVIEWS
- Protein tyrosine phosphatase SHP-2: A proto-oncogene product that promotes Ras activation
- (2009) Takashi Matozaki et al. CANCER SCIENCE
- Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
- (2009) D. L. Gibbons et al. GENES & DEVELOPMENT
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- miR-200 Regulates PDGF-D-Mediated Epithelial-Mesenchymal Transition, Adhesion, and Invasion of Prostate Cancer Cells
- (2009) Dejuan Kong et al. STEM CELLS
- The tyrosine phosphatase Shp2 (PTPN11) in cancer
- (2008) Gordon Chan et al. CANCER AND METASTASIS REVIEWS
- A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition
- (2008) C. P. Bracken et al. CANCER RESEARCH
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- Malignant Gliomas in Adults
- (2008) Patrick Y. Wen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Platelet-Derived Growth Factor-D Overexpression Contributes to Epithelial-Mesenchymal Transition of PC3 Prostate Cancer Cells
- (2008) Dejuan Kong et al. STEM CELLS
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