VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors

Survival of skin cancer stem cells requires the Ezh2 polycomb group protein

(2015) Gautam Adhikary et al.   CARCINOGENESIS

Neuropilin regulation of angiogenesis: Figure 1

(2014) Anastasia Lampropoulou et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model

(2014) Lucia Borriello et al.   CANCER LETTERS

Protein Kinase C δ Increases Kruppel-like Factor 4 Protein, which Drives Involucrin Gene Transcription in Differentiating Keratinocytes

(2013) Yap Ching Chew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VEGFA and tumour angiogenesis

(2013) L. Claesson-Welsh et al.   JOURNAL OF INTERNAL MEDICINE

Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway

(2013) Jillian C. Nissen et al.   JOURNAL OF NEUROCHEMISTRY

Role of VEGF Receptors in Normal and Psoriatic Human Keratinocytes: Evidence from Irradiation with Different UV Sources

(2013) Jian-Wei Zhu et al.   PLoS One

Identification of a Population of Epidermal Squamous Cell Carcinoma Cells with Enhanced Potential for Tumor Formation

(2013) Gautam Adhikary et al.   PLoS One

Biochemistry of epidermal stem cells

(2012) Richard L. Eckert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

VEGF Exerts an Angiogenesis-Independent Function in Cancer Cells to Promote Their Malignant Progression

(2012) Ying Cao et al.   CANCER RESEARCH

Targeting VEGF signalling via the neuropilin co-receptor

(2012) Snezana Djordjevic et al.   DRUG DISCOVERY TODAY

Vascular endothelial growth factor-induced skin carcinogenesis depends on recruitment and alternative activation of macrophages

(2012) Nina Linde et al.   JOURNAL OF PATHOLOGY

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Activation of VEGFR-2 signaling in response to moderate dose of ultraviolet B promotes survival of normal human keratinocytes

(2011) Jian-Wei Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cancer stem cells and angiogenesis

(2011) Yue Zhao et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

(2011) Benjamin Beck et al.   NATURE

Incidence Estimate of Nonmelanoma Skin Cancer in the United States, 2006

(2010) Howard W. Rogers et al.   ARCHIVES OF DERMATOLOGY

Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity

(2010) H Jia et al.   BRITISH JOURNAL OF CANCER

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

(2010) Beate M. Lichtenberger et al.   CELL

Keratinocyte stem cells: Friends and foes

(2010) Carlo Pincelli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

(2010) Ashley Jarvis et al.   JOURNAL OF MEDICINAL CHEMISTRY

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE