Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence

Vitamin D receptor expression is associated with improved overall survival in human glioblastoma multiforme

(2014) Débora G. Salomón et al.   JOURNAL OF NEURO-ONCOLOGY

The impact of vitamin D in breast cancer: genomics, pathways, metabolism

(2014) Carmen J. Narvaez et al.   Frontiers in Physiology

Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells

(2013) Monica Croke et al.   CELL CYCLE

Chromatin remodeling, BRCA1, SAHF and cellular senescence

(2013) Zhigang Tu et al.   CELL CYCLE

BRCA1 loss activates cathepsin L–mediated degradation of 53BP1 in breast cancer cells

(2013) David A. Grotsky et al.   JOURNAL OF CELL BIOLOGY

Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment

(2013) Susana Gonzalo   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

(2013) Katherine M. Aird et al.   Cell Reports

Depletion of Deoxyribonucleotide Pools Is an Endogenous Source of DNA Damage in Cells Undergoing Oncogene-Induced Senescence

(2012) Sudha Mannava et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular Mechanisms of Vitamin D Action

(2012) Mark R. Haussler et al.   CALCIFIED TISSUE INTERNATIONAL

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

(2012) Anitha Suram et al.   EMBO JOURNAL

Associations between vitamin D deficiency and risk of aggressive breast cancer in African-American women

(2012) Song Yao et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence

(2012) Z. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1 -Mutated Mouse Mammary Tumors

(2012) Janneke E. Jaspers et al.   Cancer Discovery

Regulating the levels of key factors in cell cycle and DNA repair: New pathways revealed by lamins

(2011) Abena B. Redwood et al.   CELL CYCLE

A dual role for A-type lamins in DNA double-strand break repair

(2011) Abena B. Redwood et al.   CELL CYCLE

Oncogenic Ras Regulates BRIP1 Expression to Induce Dissociation of BRCA1 from Chromatin, Inhibit DNA Repair, and Promote Senescence

(2011) Zhigang Tu et al.   DEVELOPMENTAL CELL

A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair

(2011) Ignacio Gonzalez-Suarez et al.   EMBO JOURNAL

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability

(2011) A. Aly et al.   Journal of Molecular Cell Biology

Loss of 53BP1 Is a Gain for BRCA1 Mutant Cells

(2010) Elizabeth M. Kass et al.   CANCER CELL

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer

(2010) Noel F. Lowndes   DNA REPAIR

Nuclear vitamin D receptor expression is associated with improved survival in non-small cell lung cancer

(2010) Malini Srinivasan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways

(2010) Lorena Urbanelli et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

(2009) Ignacio Gonzalez-Suarez et al.   EMBO JOURNAL

A Selective Requirement for 53BP1 in the Biological Response to Genomic Instability Induced by Brca1 Deficiency

(2009) Liu Cao et al.   MOLECULAR CELL

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

The consequences of Rad51 overexpression for normal and tumor cells

(2008) Hannah L. Klein   DNA REPAIR

Mechanisms of nuclear vitamin D receptor resistance in Harvey-ras-transfected cells

(2008) Laura M. Taber et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Prolactin Blocks Nuclear Translocation of VDR by Regulating Its Interaction with BRCA1 in Osteosarcoma Cells

(2008) Changhui Deng et al.   MOLECULAR ENDOCRINOLOGY

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

(2008) S. Rottenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA