Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

The R527H mutation in LMNA gene causes an increased sensitivity to ionizing radiation

(2011) Alessandra di Masi et al.   CELL CYCLE

Nuclear lamins: key regulators of nuclear structure and activities

(2009) Miron Prokocimer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

(2009) Laura J. Ng et al.   NUCLEIC ACIDS RESEARCH

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT

The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells

(2008) V. Raz et al.   JOURNAL OF CELL SCIENCE

Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by hTERT or Inactivation of p53

(2008) Brian A. Kudlow et al.   MOLECULAR BIOLOGY OF THE CELL

The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae

(2008) Brian Luke et al.   MOLECULAR CELL

Role for perinuclear chromosome tethering in maintenance of genome stability

(2008) Karim Mekhail et al.   NATURE

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE

Tethering by lamin A stabilizes and targets the ING1 tumour suppressor

(2008) Xijing Han et al.   NATURE CELL BIOLOGY

Lamin A/C Is a Risk Biomarker in Colorectal Cancer

(2008) Naomi D. Willis et al.   PLoS One

Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase

(2008) S. Nagai et al.   SCIENCE

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE

Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A

(2007) Shurong Huang et al.   EXPERIMENTAL CELL RESEARCH