Article
Food Science & Technology
Annick Arcelle Pougoue Ngueukam, Mathilde Julie Klang, Ronice Zokou, Gires Teboukeu Boungo, Barakat Koyinsola Azeez, Fabrice Djikeng Tonfack, Hilaire Macaire Womeni, Apollinaire Tsopmo
Summary: This study determined the structure of peptides in soy protein hydrolysates and found that the pepsin hydrolysate exhibited higher anti-radical and oxidative stability properties, while the trypsin hydrolysate showed pro-oxidant activity.
Article
Nutrition & Dietetics
Lucrecia Carrera-Quintanar, Lorena Funes, Maria Herranz-Lopez, Nestor Vicente-Salar, Raul Bonet-Garcia, Carles Blasco-Peris, Vicente Micol, Antoni Pons, Enrique Roche
Summary: This study aimed to investigate the influence of different polyphenolic antioxidant-rich beverages on five-a-side/futsal players. The results showed that oxidative stress markers significantly increased in the blood after the match, while the almond-based beverage supplemented group had significantly lower malondialdehyde levels in neutrophils compared to the control group. In conclusion, polyphenolic antioxidant and anti-inflammatory supplements could aid in optimal recovery after high-intensity futsal games.
Article
Food Science & Technology
Jurga Budiene, Gamze Guclu, Kouame Fulbert Oussou, Hasim Kelebek, Serkan Selli
Summary: The study highlighted the impact of different juice extraction methods on the phytochemical profiles, volatile compounds, and antioxidant activities of pomegranate juices. Macerated arils extraction method showed highest number of volatile compounds while halved pomegranate extraction method was preferred in terms of sensory quality.
Article
Oncology
Aya M. Hussein, Nadia M. El-Beih, Menha Swellam, Enas A. El-Hussieny
Summary: Pomegranate juice showed better chemopreventive effects on hepatocellular carcinoma, reducing antioxidant defense state and inflammatory status while inducing cell apoptosis.
CANCER CELL INTERNATIONAL
(2022)
Review
Food Science & Technology
Youling L. Xiong, Anqi Guo
Summary: Protein oxidation is a complex chemical process occurring ubiquitously in food systems, involving both radicals and nonradicals, which can affect the conformation and functionality of proteins.
Article
Nutrition & Dietetics
Hosam M. Habib, Hamada El-Gendi, Esmail M. El-Fakharany, Mohamed G. El-Ziney, Ahmed F. El-Yazbi, Fatima T. Al Meqbaali, Wissam H. Ibrahim
Summary: The polyphenolic profile of pomegranate juice concentrate was investigated for the first time, revealing its potential health benefits and antioxidant activity. The concentrate exhibited inhibitory effects on oxidative damage and enzyme activities. It also demonstrated antibacterial effects and dose-dependent apoptosis on cancer cells.
Article
Chemistry, Applied
Salvatore Genovese, Francesco Epifano, Lucia Palumbo, Chiara Collevecchio, Fabio Cardellini, Maria Bastianini, Roberto Spogli, Serena Fiorito
Summary: This study investigated the performance of various solid sorbents in the concentration of pomegranate juice. The results showed that magnesium-containing clays effectively bleached and enhanced the antioxidant capacity of pomegranate juice. The antioxidant activity of pomegranate concentrate supported on clays remained stable for 4 days.
Article
Multidisciplinary Sciences
Lucia Pappalardo
Summary: Pomegranate is a valuable source of nutrition with medicinal benefits. As the demand for pomegranate fresh fruit juices increases, the issue of adulteration becomes a concern. This study utilized UV-visible spectroscopy and multivariate statistical analysis to detect adulteration of pomegranate juice with apple juice concentrate.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Erdal Agcam
Summary: This study evaluated the degradation kinetics of phenolics in pomegranate juice under the conditions of thermosonication, and found that over thermosonication had an adverse effect on the phenolics. The results indicated that the degradation rate of anthocyanins was higher than ellagic acid, and lowering temperature and ultrasound energy density helped minimize the loss of phenolics.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2022)
Article
Food Science & Technology
Rui Xia, Liqun Wang, Ting Zhou, Yiting Zeng, Xingjie Li, Shouxun Wu, Xiaoyi Huang, Yuhong Kang, Wenya Yin
Summary: This study evaluated the effect of pomegranate juice (POMJ) in ameliorating pulmonary fibrosis (PF) and explored the underlying mechanisms. It was found that POMJ improved lung injury by regulating the inflammatory response and the process of epithelial-mesenchymal transition (EMT), indicating its potential for treating pulmonary fibrosis.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Chemistry, Multidisciplinary
Zhuoyu Wang, Andrej Svyantek, Zachariah Miller, Bridgid Jarrett, Ashley Kapus
Summary: This study examines the influence of juicing methods on the quality of 'Aurora' haskap juice. It finds that the centrifugal juicer increases the concentration of juice components, while the steam juicer decreases it. However, the pressed juice has similar to slightly lower concentrations compared to the centrifugal juicer.
APPLIED SCIENCES-BASEL
(2023)
Article
Environmental Sciences
Shokoofeh Hajihashemi, Shakiba Rajabpoor, Henk Schat
Summary: High concentrations of minerals in soil near a copper mine in Iran caused chlorosis and reduced growth in pomegranate trees. The chlorotic trees showed increased levels of toxic elements such as copper, iron, and zinc, while manganese levels were significantly decreased. The chlorosis in the trees may be caused by toxicity of certain elements or a deficiency of manganese. Additionally, acid mine drainage led to oxidative stress and lipid peroxidation in the affected trees.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Sadia Kafeel, Muhammad Inam-ur-Raheem, Moazzam Rafiq Khan, Muhammad Naeem Faisal
Summary: Pomegranate peel, a biological waste, is rich in gallic acid, catechin, and quercetin, which have therapeutic effects. This study evaluated the extracts from two cultivars, Badana and Kandhari, finding that Badana extract had the highest phenolics, flavonoids, and antioxidant activity. HPLC analysis showed the presence of various bioactive compounds, with gallic acid being the most abundant in Badana extract. Overall, the 70% hydroethanolic Badana extract is a valuable source of bioactive components.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Dora Tatraaljai, Yun Tang, Emese Pregi, Erika Vagi, Viola Horvath, Bela Pukanszky
Summary: In this study, the processing stabilization efficiency of pomegranate peel extract on polyethylene was investigated. The results showed that while the extract improved the processing stabilization, it had a negative impact on the long-term stability. This could be attributed to chemical factors and the lack of necessary reactive hydrogens.
Article
Biochemistry & Molecular Biology
Valerija Vujcic Bok, Marko Geric, Goran Gajski, Sanja Gagic, Ana-Marija Domijan
Summary: The aim of this study was to investigate the phytotoxicity and mode of action of bisphenol A (BPA) on Allium cepa roots using a multibiomarker approach. The results showed that even at the lowest concentration tested (1 mg L-1), BPA significantly reduced root length, root fresh weight, and mitotic index. Additionally, it was found that BPA at this concentration also decreased the level of gibberellic acid (GA(3)) in root cells. Higher concentrations of BPA (5 mg L-1) induced production of reactive oxygen species (ROS), oxidative damage to lipids and proteins, and activity of superoxide dismutase. Concentrations of BPA above 25 mg L-1 caused genome damage and synthesis of phytochemicals. These findings highlight the phytotoxic and genotoxic potential of BPA in plants and emphasize the need for environmental monitoring.
Review
Environmental Sciences
Alfredo Cordova-Martinez, Alberto Caballero-Garcia, Enrique Roche, Daniel Perez-Valdecantos, David C. Noriega
Summary: Athletes who have had COVID-19 face risks related to neuromuscular issues and require gradual recovery to optimal conditions for training and competition.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Alfredo Cordova, Alberto Caballero-Garcia, David Noriega-Gonzalez, Hugo J. Bello, Antoni Pons, Enrique Roche
Summary: Calcium, magnesium, vitamin D, and hormones play important roles in muscle function and physical fitness. This study investigates the effects of NO precursor supplementation on the circulating levels of these nutrients and hormones in elders. The results suggest that vasodilators, such as L-arginine and beetroot extract, can increase vitamin D levels and potentially improve muscular function in the long term.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Biochemistry & Molecular Biology
Diego Herrero, Guillermo Albericio, Marina Higuera, Maria Herranz-Lopez, Miguel A. Garcia-Brenes, Alejandra Cordero, Enrique Roche, Pilar Sepulveda, Carmen Mora, Antonio Bernad
Summary: Research on the interaction of adult cardiac progenitor cells with other cardiac cell populations can define the vascular cardiac stem cell niche, which is associated with low oxidative stress domains in vasculature, and manipulating this niche may offer new hope in the cardiac regeneration field.
Article
Nutrition & Dietetics
Lucrecia Carrera-Quintanar, Lorena Funes, Maria Herranz-Lopez, Nestor Vicente-Salar, Raul Bonet-Garcia, Carles Blasco-Peris, Vicente Micol, Antoni Pons, Enrique Roche
Summary: This study aimed to investigate the influence of different polyphenolic antioxidant-rich beverages on five-a-side/futsal players. The results showed that oxidative stress markers significantly increased in the blood after the match, while the almond-based beverage supplemented group had significantly lower malondialdehyde levels in neutrophils compared to the control group. In conclusion, polyphenolic antioxidant and anti-inflammatory supplements could aid in optimal recovery after high-intensity futsal games.
Review
Nutrition & Dietetics
Alfredo Cordova, Franchek Drobnic, David Noriega-Gonzalez, Alberto Caballero-Garcia, Enrique Roche, Melchor Alvarez-Mon
Summary: Physical activity and sports increase the risk of tendinopathies due to the stress and force generated in the tendon and muscle-tendon unit. Curcumin, a supplement, has been found to have significant anti-pain, anti-inflammatory, and antioxidant effects, and can promote the inflammatory and regenerative response in tendinopathies. Additionally, curcumin can reduce cell infiltration, activation, and production of pro-inflammatory mediators at the site of inflammation.
Article
Biochemistry & Molecular Biology
Yoel Genaro Montoyo-Pujol, Marta Garcia-Escolano, Jose J. Ponce, Silvia Delgado-Garcia, Tina Aurora Martin, Hortensia Ballester, Elena Castellon-Molla, Pascual Martinez-Peinado, Sandra Pascual-Garcia, Jose Miguel Sempere-Ortells, Gloria Peiro
Summary: Advances in immunotherapy have led to increased interest in studying the role of the immune system in breast cancer. This study evaluated the expression of various immune regulation genes in different breast cancer cell lines and mammospheres. The results showed that the expression of these genes varied depending on the breast cancer phenotype, culture conditions, and interaction with immune cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Nutrition & Dietetics
Diego Fernandez-Lazaro, Carlos Dominguez-Ortega, Natalia Busto, Mirian Santamaria-Pelaez, Enrique Roche, Eduardo Gutierez-Abejon, Juan Mielgo-Ayuso
Summary: N-acetylcysteine (NAC) is a sports supplement that can improve physical performance by modulating exercise-induced oxidative damage and maintaining glutathione homeostasis. A systematic review of studies on NAC supplementation in adult men found that it has beneficial effects on exercise performance, antioxidant capacity, and glutathione homeostasis. However, the evidence for its effects on haematological markers, inflammatory response, and muscle behavior is not clear. Overall, NAC supplementation appears to be safe and effective, but more research is needed to fully understand its relevance.
Review
Nutrition & Dietetics
Alberto Caballero-Garcia, David C. Noriega-Gonzalez, Enrique Roche, Franchek Drobnic, Alfredo Cordova
Summary: Exercise-induced muscle damage leads to decreased physical performance and an inflammatory response in muscle tissue. L-carnitine supplementation has the potential to improve postexercise recovery by reducing oxidative damage and inflammation. However, further research is needed to fully understand the mechanisms underlying these effects and evaluate its efficacy on fatigue perception and muscle soreness.
Review
Medicine, General & Internal
David Noriega-Gonzalez, Alberto Caballero-Garcia, Enrique Roche, Melchor alvarez-Mon, Alfredo Cordova
Summary: Osteoarthritis is a joint disorder characterized by stress and degradation of cartilage, resulting from failed repair of micro- and macro-lesions. Knee osteoarthritis affects joint tissues, leading to structural, biochemical, and biomechanical changes. Symptoms include pain, deformation, disability, and inflammation. Repetitive concentric movements, like cycling, can contribute to microtrauma and progression of cartilage damage. This review aims to explain the development of knee osteoarthritis in cyclists, highlight the lack of research in this area, and propose future therapeutic strategies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Health Care Sciences & Services
Alfredo Cordova, Alberto Caballero-Garcia, Franchek Drobnic, Enrique Roche, David C. Noriega
Summary: Emotional instability and stress are major disturbances in the learning process, affecting both teachers and students. This review analyzes the influence of stress and emotions on the learning environment. Stress is a physiological mechanism for adapting and surviving challenges. While chronic stress is seen as negative, controlled stress can enhance learning. The intensity and quality of emotions resulting from stress also influence the learning process. Positive emotions promote optimal learning, leading to changes in cognition, behavior, and physiology. Activation of coping strategies is essential for managing stress and generating positive emotions, promoting effective learning through improved attention and problem-solving abilities.
Article
Biochemistry & Molecular Biology
Sandra Pascual-Garcia, Pascual Martinez-Peinado, Ana B. B. Lopez-Jaen, Francisco J. J. Navarro-Blasco, Yoel G. G. Montoyo-Pujol, Enrique Roche, Gloria Peiro, Jose M. Sempere-Ortells
Summary: This study aimed to identify severity biomarkers to predict flare-ups or remission periods in rheumatoid arthritis (RA) patients. The study found that elevated percentages of CD3(+)CD4(-) lymphocytes and granulocytes, as well as a decreased NK/T lymphocyte ratio, can differentiate between flare-up and remission. Therefore, the combined study of leukocyte surface markers could be potential disease severity biomarkers for RA.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Anatomy & Morphology
Alicia Navarro-Sempere, Magdalena Garcia, Encarnacion Garcia, Daniela Jimenez, Vanessa Pinilla, Ana Belen Lopez-Jaen, Pascual Martinez-Peinado, Sandra Pascual-Garcia, Jose Miguel Sempere, Yolanda Segovia
Summary: The incorporation of gamification strategies in teaching can increase student motivation and engagement. An educational innovation experience was conducted using the Kahoot! platform in a Cell Biology course. The results showed that students who participated in the gamified teaching approach had a higher number of correct answers in the post-test compared to those who did not.
INTERNATIONAL JOURNAL OF MORPHOLOGY
(2022)
Review
Nutrition & Dietetics
David C. Noriega-Gonzalez, Franchek Drobnic, Alberto Caballero-Garcia, Enrique Roche, Daniel Perez-Valdecantos, Alfredo Cordova
Summary: Tendinopathies account for 30-50% of all sports injuries, with collagen I being the main component of tendons. Vitamin C supplementation potentially aids in tendinopathy recovery by increasing collagen synthesis, while vitamin C deficiency hinders tendon repair by reducing procollagen synthesis and hydroxylation of specific residues.
Article
Psychology, Multidisciplinary
Daniel Perez-Valdecantos, Alberto Caballero-Garcia, Hugo J. Bello, David Noriega-Gonzalez, Nora Palomar-Ciria, Alba Roche, Enrique Roche, Alfredo Cordova-Martinez
Summary: Previous studies have shown that professionals in emergency departments experience high levels of stress, which can be counteracted by increased levels of dehydroepiandrosterone. This study aimed to evaluate the quality of life of health professionals working in emergency departments in two Spanish hospitals. The results indicate that these professionals have a good perception of professional quality of life, with adequate professional management and levels of stress, sleep, and quality of life in line with a controlled lifestyle. However, the COVID-19 pandemic has disrupted this controlled professional management.
BEHAVIORAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Sarah Maria Barneze Costa, Raghavendra Lakshmana Shetty Hallur, David Rafael Abreu Reyes Postdoc, Juliana Ferreira Floriano Postdoc, Maria Antonieta de Barros Leite Carvalhaes, Helio Rubens de Carvalho Nunes, Luis Sobrevia, Paola Valero, Angelica Mercia Pascon Barbosa, Marilza Cunha Vieira Rudge
Summary: This study aimed to assess maternal dietary intake patterns, anthropometric measures, and biochemical markers in women with gestational diabetes mellitus and pregnancy-specific urinary incontinence. The results showed that pregnant women in the gestational diabetes mellitus pregnancy-specific urinary incontinence group had higher body mass index, arm circumference, and triceps skinfold than the other groups, indicating an obesogenic maternal environment. Significant differences in dietary food intake were also observed. The study emphasizes the need for a comprehensive strategy for pregnant women with gestational diabetes mellitus and pregnancy-specific urinary incontinence to address obesity and micronutrient deficiencies.
Article
Nutrition & Dietetics
Aikaterina Vasileiou, Dominique Searle, Sofus C. Larsen, Faidon Magkos, Graham Horgan, R. James Stubbs, Ines Santos, Antonio L. Palmeira, Berit L. Heitmann
Summary: The study compared self-reported total energy intake with total energy expenditure estimated from Fitbit Charge 2 algorithms. The results showed that self-reported energy intake was generally lower than energy expenditure, and the degree of underestimation varied among different populations.
Article
Nutrition & Dietetics
Ziya Erokay Metin, Ozge Mengi Celik, Nevra Koc
Summary: This study demonstrates a significant relationship between climate change awareness and sustainable and healthy eating behaviors as well as adherence to the Mediterranean diet.
Article
Nutrition & Dietetics
Carolline Santos Miranda, Flavia Maria Silva-Veiga, Daiana Araujo Santana-Oliveira, Isabela Macedo Lopes Vasques-Monteiro, Julio Beltrame Daleprane, Vanessa Souza-Mello
Summary: This study investigates the role of peroxisome proliferator-activated receptor (PPAR) activation on thermogenic pathways and mitochondrial metabolism in mouse adipose tissue. The results show that activation of PPARa and dual PPARa/y can reduce body mass, mitigate insulin resistance, and induce browning in white adipose tissue. Preserved mitochondrial metabolism emerges as a potential target for obesity treatment using PPAR agonists, with possible clinical applications.
Article
Nutrition & Dietetics
Qi Ren, Hao-Fan Wu, Ding-Ye Yu, Feng-Min Zhang, Zi-Le Shen, Guo-Wei Huang, Feng Lin, Wei-Zhe Chen, Zhen Yu
Summary: The study aimed to develop a nomogram incorporating preoperative factors for predicting low skeletal muscle mass index and low skeletal muscle radiodensity. The models were calibrated and assessed for their predictive ability using training and validation cohorts, and the clinical usefulness was evaluated using decision curve analysis.
Article
Nutrition & Dietetics
Ruben Castillo-Ortega, Juan Vega-Vargas, Samuel Duran-Aguero
Summary: This study found that during the COVID-19 pandemic, patients with type 1 diabetes experienced decreased adherence to diabetes care, leading to an increase in HbA1c levels, BMI, impaired linear growth, and more hospitalizations. The shift to telemedicine as the main healthcare service also had significant effects on diabetes management.
Article
Nutrition & Dietetics
Yi-Hsiu Chen, Jung-An Lin, Jiun-Rong Chen, Ya-Ling Chen, Suh-Ching Yang
Summary: Regular nutrition consultations have been shown to have significant effects on reducing cardiovascular disease risk factors, especially for individuals with obesity.
Article
Nutrition & Dietetics
Jacinta Winderlich, Bridget Little, Felix Oberender, Tessa Bollard, Tamara Farrell, Samantha Jenkins, Emma Landorf, Andrea McCall, Jessica Menzies, Katie O. ' Brien, Carla Rowe, Kirsten Sim, Melanie van der Wilk, Jemma Woodgate, Eldho Paul, Andrew A. Udy, Emma J. Ridley
Summary: The study aims to describe nutrition provision in Australian and New Zealand pediatric intensive care units, assess the adequacy of enteral nutrition, and evaluate the methods for estimating energy and protein requirements.
Article
Nutrition & Dietetics
Xi Zhang, Jia-Xin Huang, Meng Tang, Qi Zhang, Li Deng, Chun-Hua Song, Wei Li, Han-Ping Shi, Ming-Hua Cong
Summary: The study found that the modified Controlling Nutritional Status system, which includes C-reactive protein as an inflammatory parameter, is more accurate than the traditional system in predicting the survival of patients with cancer cachexia. High Controlling Nutritional Status and modified Controlling Nutritional Status are both independent risk factors for survival and have a negative impact on survival in patients with advanced-stage cancers, such as esophagogastric and colorectal cancer.
Article
Nutrition & Dietetics
Karolien Dams, Gregory R. A. De Meyer, Rita Jacobs, Tom Schepens, Stany Perkisas, Greta Moorkens, Philippe Jorens
Summary: The study aimed to investigate the development of muscle atrophy in COVID-19 intensive care unit patients and its relationship with hospital outcomes. The results showed that the difference in muscle thickness was linked to the outcome, with the best survival observed in the group with stable muscle thickness.
Article
Nutrition & Dietetics
Bruna Clemente Cota, Mariana de Santis Filgueiras, Patricia Feliciano Pereira, Leidjaira Lopes Juvanhol, Juliana Farias de Novaes
Summary: This study found that higher consumption of ultra-processed food (UPF) and a diet consisting of high proinflammatory foods were associated with the normal-weight obesity (NWO) phenotype in children.
Article
Nutrition & Dietetics
Victor Nogueira da Cruz Silveira, Cleber Lopes Campelo, Antonio Luis Rodrigues da Costa, Patricia Maria Abreu Machado, Ana Karina Teixeira da Cunha Franca, Alcione Miranda dos Santos
Summary: This psychometric study proposed a scale for estimating the consumption of ultra processed foods using item response theory. The study used data from a representative sample of 2515 adolescents aged 18 and 19 from Brazilian Birth Cohorts Consortium. The findings demonstrated that the proposed scale can accurately estimate the consumption of ultra processed foods and is correlated with latent traits related to food consumption.
Article
Nutrition & Dietetics
Dehao Yang, Jiaqi Huang, Jingyu Hu, Minyue Zhang, Haobo Xie, Yilin Chen, Yining Jin, Zerui Jiang, Yanchu Wang, Jinrong Zhu, Xin Lu, Siqi Chen, Yiyun Weng, Guangyong Chen
Summary: This study investigates the association between malnutrition and 6-month outcomes in acute ischemic stroke patients with or without intravenous thrombolysis. The results show a significant association between malnutrition and poor functional outcome.
Article
Nutrition & Dietetics
Ainoa Cristina de Oliveira Candido, Felipe Silva Neves, Vanessa Sequeira Fontes, Adriana Soares Torres Melo, Eliane Rodrigues de Faria, Michele Pereira Netto, Renata Maria Souza Oliveira, George Luiz Lins Machado-Coelho, Ana Paula Carlos Candido
Summary: This study investigated the frequency of breakfast consumption and its associations with the consumption of food at different degrees of industrial processing and with overweight indicators in Brazilian adolescents. The results showed that 20% of adolescents skipped breakfast and 46% of their caloric intake came from ultra-processed foods. Skipping breakfast was associated with increased consumption of ultra-processed foods, higher BMI-for-age, and higher body fat percentage.