Article
Biochemistry & Molecular Biology
Mosaab Salah El-din El-Agawy, Alaa Mohamed Mohamed Badawy, Mohammed R. Rabei, Mohamed Mahmoud Abdelraheem Elshaer, Eman Mohamad El Nashar, Mansour A. Alghamdi, Mohammed A. Alshehri, Hassan Reda Hassan Elsayed
Summary: LC-PUFA plays a beneficial role in preventing the adverse effects of MTX on the kidneys through its anti-apoptotic, antioxidant, and anti-inflammatory effects, as well as its role in restoring the expression of AQPs 1 and 2.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Doaa El Amrousy, Dalia El-Afify, Rasha Khedr, Ashraf Mohamed Ibrahim
Summary: The study suggests that omega-3 fatty acids may reduce early cardiac injury and doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukemia (ALL).
PEDIATRIC BLOOD & CANCER
(2022)
Review
Nutrition & Dietetics
Ivana Djuricic, Philip C. Calder
Summary: Oxidative stress and inflammation are important contributors to chronic non-communicable diseases. Different types of fatty acids have varying effects on chronic diseases, with moderate intake of Ω-6 fatty acids lowering the risk of cardiovascular diseases and Ω-3 fatty acids helping to reduce inflammation levels.
Article
Oncology
Matteo Pederzolli, Fabio Giglio, Maria Vittoria Cicinelli, Alessandro Marchese, Giulio Modorati, Sara Mastaglio, Fabio Ciceri, Francesco Bandello, Elisabetta Miserocchi
Summary: Direct leukemic infiltration of the eye, often associated with acute lymphoblastic leukemia, may not be effectively treated with systemic therapy alone. Intravitreal methotrexate injections show promise as a therapeutic option for intraocular leukemia, though further evidence is needed to solidify its use in this debilitating localization.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Renate D. Laumann, Turid Iversen, Pernille R. Mogensen, Lotte Lauritzen, Christian Molgaard, Thomas L. Frandsen
Summary: Hyperlipidemia is common during childhood acute lymphoblastic leukemia treatment and may lead to serious complications. The study suggests that fish oil supplementation could potentially lower triglycerides and total cholesterol levels in these patients, with further research needed to confirm these findings and assess the impact on adverse events.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2021)
Article
Nutrition & Dietetics
Lourdes Barbosa-Cortes, Ximena Martinez-Vieyra, Juan Manuel Mejia-Arangure, Mardia Lopez-Alarcon, Jorge Martin-Trejo, Suily Delgadillo-Portillo, Brenda Guzman-Castro, Jazmin Delgadillo-Portillo, Salvador Atilano-Miguel, Maricela Rodriguez-Cruz, Jorge Maldonado-Hernandez, Ana Anoveros-Barrera, Karina A. Solis-Labastida, Laura Espinoza-Hernandez, Nora N. Nunez-Villegas, Elva Jimenez-Hernandez, Benito A. Bautista-Martinez, Azalia Juarez-Moya, Zayra Hernandez-Pinon, Ruy Xavier Perez-Casillas
Summary: This study investigates the effect of LCPUFA-omega 3 supplementation on body composition changes in children with acute lymphoblastic leukemia (ALL). The results show that LCPUFA-omega 3 supplementation helps decrease the loss of fat mass and lean mass in ALL children during remission and three months after supplementation.
CLINICAL NUTRITION
(2023)
Article
Immunology
Siyao Jin, Jiamin Xu, Yaru Zou, Xiaona Li, Boran Yu, Jiaqi Han, Xiaoling Wang, Libo Zhao
Summary: This study aimed to explore the association between the anti-inflammatory effects of 6-MP and gut microbiome changes, and their impact on inflammasome. Using a mouse model, it was proved that 6-MP has anti-tumor effects and can significantly decrease the levels of pro-inflammatory factors IL6 and TNF-α. The levels of short-chain fatty acids and the composition of gut microbiota were found to be correlated with the anti-inflammatory response of 6-MP.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Kamila P. Liput, Adam Lepczynski, Magdalena Ogluszka, Agata Nawrocka, Ewa Polawska, Agata Grzesiak, Brygida Slaska, Chandra S. Pareek, Urszula Czarnik, Mariusz Pierzchala
Summary: It is recommended to reduce saturated fatty acids (SFA) and increase polyunsaturated fatty acids (PUFAs) n-3 and n-6 in the diet to lower the risk of metabolic disorders. Western-type diet often contains excessive n-6 PUFAs and a high n-6/n-3 ratio. Oxylipins derived from n-3 and n-6 PUFAs play a role in inflammation, while PUFAs have varying effects on cell growth, proliferation, and neoplastic lesion progression, as observed in in vitro studies, animal models, and epidemiological studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Obstetrics & Gynecology
J. Stanhiser, A. M. Z. Jukic, D. R. McConnaughey, A. Z. Steiner
Summary: The study found that self-reported use of omega-3 fatty acid supplements was associated with an increased probability of conceiving.
HUMAN REPRODUCTION
(2022)
Article
Engineering, Chemical
Muhammad Abdul Rahim, Muhammad Imran, Muhammad Kamran Khan, Muhammad Haseeb Ahmad, Muhammad Nadeem, Waseem Khalid, Jose Manuel Lorenzo, Mohamed M. Afifi, Ammar AL-Farga, Moneera O. Aljobair
Summary: Omega-3 fatty acids are essential and cannot be synthesized by the body. Therefore, this study used spray drying to prepare more stable microcapsules of omega-3 fatty acids, which can improve the oxidative stability of food products.
Review
Biochemistry & Molecular Biology
Roberta Cardim Lessa, Fabio de Abreu Alves, Erika Fortunati, Jun Lu
Summary: Oral mucositis (OM) is a painful condition caused by cancer treatments, impacting patients' quality of life and recovery. Current management strategies are insufficient, necessitating a search for new approaches. Utilizing ω-3 fatty acids to manage OM may be an effective strategy based on preliminary evidence.
Article
Biotechnology & Applied Microbiology
Ramachandran Sivaramakrishnan, Aran Incharoensakdi
Summary: The high potential Chlorella sp. with higher biomass and lipid content than the wild type was obtained through UV mutation. Hydrogen peroxide (H2O2) treatment further increased both biomass and lipid content in the mutant, while the wild type showed no significant change. The treated mutant cells showed a 3-fold increase in total lipid yield compared to the untreated wild type, and the fatty acid composition of lipids was also altered, resulting in enhanced omega-3 fatty acids.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Review
Nutrition & Dietetics
Daniel Rodriguez, Carl J. Lavie, Andrew Elagizi, Richard V. Milani
Summary: This paper discusses the importance of using omega-3 fatty acids in cardiovascular diseases and summarizes related research and recommendations.
Review
Psychiatry
Katherine H. O. Deane, Oluseyi F. Jimoh, Priti Biswas, Alex O'Brien, Sarah Hanson, Asmaa S. Abdelhamid, Chris Fox, Lee Hooper
Summary: The study found that increasing long-chain Omega-3 has little or no effect on preventing depression and anxiety symptoms, while increasing alpha-linolenic acid may slightly increase the risk of depression symptoms, but with low-quality evidence.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Biochemistry & Molecular Biology
Kaitlyn B. Hartnett, Bradley J. Ferguson, Patrick M. Hecht, Luke E. Schuster, Joel I. Shenker, David R. Mehr, Kevin L. Fritsche, Martha A. Belury, Douglas W. Scharre, Adam J. Horwitz, Briana M. Kille, Briann E. Sutton, Paul E. Tatum, C. Michael Greenlief, David Q. Beversdorf
Summary: This pilot study aimed to explore the relationship between stress exposure and dietary omega-3 fatty acid intake in relation to the risk of Alzheimer's disease (AD). The results showed that among individuals with high stress exposure, healthy controls had significantly higher omega-3 fatty acid intake compared to AD patients. No difference was observed among those with low stress exposure. These preliminary findings suggest that omega-3 fatty acids may mitigate AD risk in the setting of greater stress exposure.
Article
Hematology
Nagham Mohamed Samy El-beblawy, Nancy Samir Elbarbary, Tarek Mostafa Kamal, Perehan Mohsen Mahmoud
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
(2016)
Article
Endocrinology & Metabolism
Lourdes Ibanez, Sharon E. Oberfield, Selma F. Witchel, Richard J. Auchus, R. Jeffrey Chang, Ethel Codner, Preeti Dabadghao, Feyza Darendeliler, Nancy Samir Elbarbary, Alessandra Gambineri, Cecilia Garcia Rudaz, Kathleen M. Hoeger, Abel Lopez-Bermejo, Ken Ong, Alexia S. Pena, Thomas Reinehr, Nicola Santoro, Manuel Tena-Sempere, Rachel Tao, Bulent O. Yildiz, Haya Alkhayyat, Asma Deeb, Dipesalema Joel, Reiko Horikawa, Francis de Zegher, Peter A. Lee
HORMONE RESEARCH IN PAEDIATRICS
(2017)
Article
Endocrinology & Metabolism
Zeinab A. Elkabbany, Nancy S. Elbarbary, Eman A. Ismail, Nesrine A. Mohamed, Dina Ragab, Shereen Abdel Alem, Yasmine M. Ezzat, Sarah S. Maurice, Noha U. Hashem
JOURNAL OF DIABETES AND ITS COMPLICATIONS
(2017)
Article
Endocrinology & Metabolism
Nancy Samir Elbarbary, Eman Abdel Rahman Ismail, Abdel Rahman El-Naggar, Mahitab Hany Hamouda, Manal El-Hamamsy
PEDIATRIC DIABETES
(2018)
Correction
Endocrinology & Metabolism
Matthew B. Johnson, Elisa De Franco, Hana Lango Allen, Aisha Al Senani, Nancy Elbarbary, Zeynep Siklar, Merih Berberoglu, Zineb Imane, Alireza Haghighi, Zahra Razavi, Irfan Ullah, Saif Alyaarubi, Daphne Gardner, Sian Ellard, Andrew T. Hattersley, Sarah E. Flanagan
Article
Immunology
Nancy Samir Elbarbary, Eman Abdel Rahman Ismail, Rana Ahmed El-Hilaly, Fatma Salama Ahmed
INTERNATIONAL IMMUNOPHARMACOLOGY
(2018)
Article
Endocrinology & Metabolism
Farid H. Mahmud, Nancy S. Elbarbary, Elke Froehlich-Reiterer, Reinhard W. Holl, Olga Kordonouri, Mikael Knip, Kimber Simmons, Maria E. Craig
PEDIATRIC DIABETES
(2018)
Article
Nutrition & Dietetics
Nancy Samir Elbarbary, Eman Abdel Rahman Ismail, Mamdouh Ahmed Zaki, Yasser Wagih Darwish, Marwa Zaki Ibrahim, Manal El-Hamamsy
CLINICAL NUTRITION
(2020)
Article
Nutrition & Dietetics
Randa Mahmoud Matter, Nancy Samir Elbarbary, Eman Abdel Rahman Ismail, Yasser Wagih Darwish, Ahmed Shafik Nada, Veronia Philip Banoub
Article
Endocrinology & Metabolism
Nancy Samir Elbarbary, Tiago Jeronimo dos Santos, Carine de Beaufort, Juliana Chizo Agwu, Luis Eduardo Calliari, Andrea Enzo Scaramuzza
PEDIATRIC DIABETES
(2020)
Article
Endocrinology & Metabolism
Nancy Elbarbary, Othmar Moser, Saif Al Yaarubi, Hussain Alsaffar, Adnan Al Shaikh, Ramzi A. Ajjan, Asma Deeb
Summary: Early control of blood glucose is crucial in reducing vascular complications in individuals with Type 1 diabetes. Encouraging children and adolescents with T1DM to take charge of controlling glucose levels is important but challenging. The use of continuous glucose monitoring systems allows for comprehensive analysis of blood glucose levels in T1D patients and can help them take actions to maintain glucose levels near physiological levels.
DIABETES & VASCULAR DISEASE RESEARCH
(2021)
Article
Endocrinology & Metabolism
Nancy Samir Elbarbary, Yasmine Ibrahim Elhenawy, Ali Rezq Reyd Ali, Carmel E. Smart
Summary: The study found that using split insulin boluses after Iftar meal could optimize blood sugar levels effectively. By splitting 20% of insulin into two injections, both early and delayed postprandial glucose excursions were significantly reduced.
PEDIATRIC DIABETES
(2022)
Article
Endocrinology & Metabolism
Nancy Samir Elbarbary, Eman Abdel Rahman Ismail
Summary: This study evaluated the real-world performance of the MiniMed (TM) 780G system among Egyptian patients with type 1 diabetes. The results showed improved glycemic control and increased time spent in auto mode after using the system for six months.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Endocrinology & Metabolism
Nancy Samir Elbarbary, Eman Abdel Rahman Ismail
Summary: This study investigated the efficacy and safety of vildagliptin as an add-on therapy for glucose excursions during Ramadan Iftar meals in adolescents and young adults with type 1 diabetes mellitus. Results showed that vildagliptin reduced post-meal glucose surges and increased time in range, while decreasing time above range without increasing the risk of hypoglycemia.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Endocrinology & Metabolism
Matthew B. Johnson, Elisa De Franco, Hana Lango Allen, Aisha Al Senani, Nancy Elbarbary, Zeynep Siklar, Merih Berberoglu, Zineb Imane, Alireza Haghighi, Zahra Razavi, Irfan Ullah, Saif Alyaarubi, Daphne Gardner, Sian Ellard, Andrew T. Hattersley, Sarah E. Flanagan
Article
Nutrition & Dietetics
Sarah Maria Barneze Costa, Raghavendra Lakshmana Shetty Hallur, David Rafael Abreu Reyes Postdoc, Juliana Ferreira Floriano Postdoc, Maria Antonieta de Barros Leite Carvalhaes, Helio Rubens de Carvalho Nunes, Luis Sobrevia, Paola Valero, Angelica Mercia Pascon Barbosa, Marilza Cunha Vieira Rudge
Summary: This study aimed to assess maternal dietary intake patterns, anthropometric measures, and biochemical markers in women with gestational diabetes mellitus and pregnancy-specific urinary incontinence. The results showed that pregnant women in the gestational diabetes mellitus pregnancy-specific urinary incontinence group had higher body mass index, arm circumference, and triceps skinfold than the other groups, indicating an obesogenic maternal environment. Significant differences in dietary food intake were also observed. The study emphasizes the need for a comprehensive strategy for pregnant women with gestational diabetes mellitus and pregnancy-specific urinary incontinence to address obesity and micronutrient deficiencies.
Article
Nutrition & Dietetics
Aikaterina Vasileiou, Dominique Searle, Sofus C. Larsen, Faidon Magkos, Graham Horgan, R. James Stubbs, Ines Santos, Antonio L. Palmeira, Berit L. Heitmann
Summary: The study compared self-reported total energy intake with total energy expenditure estimated from Fitbit Charge 2 algorithms. The results showed that self-reported energy intake was generally lower than energy expenditure, and the degree of underestimation varied among different populations.
Article
Nutrition & Dietetics
Ziya Erokay Metin, Ozge Mengi Celik, Nevra Koc
Summary: This study demonstrates a significant relationship between climate change awareness and sustainable and healthy eating behaviors as well as adherence to the Mediterranean diet.
Article
Nutrition & Dietetics
Carolline Santos Miranda, Flavia Maria Silva-Veiga, Daiana Araujo Santana-Oliveira, Isabela Macedo Lopes Vasques-Monteiro, Julio Beltrame Daleprane, Vanessa Souza-Mello
Summary: This study investigates the role of peroxisome proliferator-activated receptor (PPAR) activation on thermogenic pathways and mitochondrial metabolism in mouse adipose tissue. The results show that activation of PPARa and dual PPARa/y can reduce body mass, mitigate insulin resistance, and induce browning in white adipose tissue. Preserved mitochondrial metabolism emerges as a potential target for obesity treatment using PPAR agonists, with possible clinical applications.
Article
Nutrition & Dietetics
Qi Ren, Hao-Fan Wu, Ding-Ye Yu, Feng-Min Zhang, Zi-Le Shen, Guo-Wei Huang, Feng Lin, Wei-Zhe Chen, Zhen Yu
Summary: The study aimed to develop a nomogram incorporating preoperative factors for predicting low skeletal muscle mass index and low skeletal muscle radiodensity. The models were calibrated and assessed for their predictive ability using training and validation cohorts, and the clinical usefulness was evaluated using decision curve analysis.
Article
Nutrition & Dietetics
Ruben Castillo-Ortega, Juan Vega-Vargas, Samuel Duran-Aguero
Summary: This study found that during the COVID-19 pandemic, patients with type 1 diabetes experienced decreased adherence to diabetes care, leading to an increase in HbA1c levels, BMI, impaired linear growth, and more hospitalizations. The shift to telemedicine as the main healthcare service also had significant effects on diabetes management.
Article
Nutrition & Dietetics
Yi-Hsiu Chen, Jung-An Lin, Jiun-Rong Chen, Ya-Ling Chen, Suh-Ching Yang
Summary: Regular nutrition consultations have been shown to have significant effects on reducing cardiovascular disease risk factors, especially for individuals with obesity.
Article
Nutrition & Dietetics
Jacinta Winderlich, Bridget Little, Felix Oberender, Tessa Bollard, Tamara Farrell, Samantha Jenkins, Emma Landorf, Andrea McCall, Jessica Menzies, Katie O. ' Brien, Carla Rowe, Kirsten Sim, Melanie van der Wilk, Jemma Woodgate, Eldho Paul, Andrew A. Udy, Emma J. Ridley
Summary: The study aims to describe nutrition provision in Australian and New Zealand pediatric intensive care units, assess the adequacy of enteral nutrition, and evaluate the methods for estimating energy and protein requirements.
Article
Nutrition & Dietetics
Xi Zhang, Jia-Xin Huang, Meng Tang, Qi Zhang, Li Deng, Chun-Hua Song, Wei Li, Han-Ping Shi, Ming-Hua Cong
Summary: The study found that the modified Controlling Nutritional Status system, which includes C-reactive protein as an inflammatory parameter, is more accurate than the traditional system in predicting the survival of patients with cancer cachexia. High Controlling Nutritional Status and modified Controlling Nutritional Status are both independent risk factors for survival and have a negative impact on survival in patients with advanced-stage cancers, such as esophagogastric and colorectal cancer.
Article
Nutrition & Dietetics
Karolien Dams, Gregory R. A. De Meyer, Rita Jacobs, Tom Schepens, Stany Perkisas, Greta Moorkens, Philippe Jorens
Summary: The study aimed to investigate the development of muscle atrophy in COVID-19 intensive care unit patients and its relationship with hospital outcomes. The results showed that the difference in muscle thickness was linked to the outcome, with the best survival observed in the group with stable muscle thickness.
Article
Nutrition & Dietetics
Bruna Clemente Cota, Mariana de Santis Filgueiras, Patricia Feliciano Pereira, Leidjaira Lopes Juvanhol, Juliana Farias de Novaes
Summary: This study found that higher consumption of ultra-processed food (UPF) and a diet consisting of high proinflammatory foods were associated with the normal-weight obesity (NWO) phenotype in children.
Article
Nutrition & Dietetics
Victor Nogueira da Cruz Silveira, Cleber Lopes Campelo, Antonio Luis Rodrigues da Costa, Patricia Maria Abreu Machado, Ana Karina Teixeira da Cunha Franca, Alcione Miranda dos Santos
Summary: This psychometric study proposed a scale for estimating the consumption of ultra processed foods using item response theory. The study used data from a representative sample of 2515 adolescents aged 18 and 19 from Brazilian Birth Cohorts Consortium. The findings demonstrated that the proposed scale can accurately estimate the consumption of ultra processed foods and is correlated with latent traits related to food consumption.
Article
Nutrition & Dietetics
Dehao Yang, Jiaqi Huang, Jingyu Hu, Minyue Zhang, Haobo Xie, Yilin Chen, Yining Jin, Zerui Jiang, Yanchu Wang, Jinrong Zhu, Xin Lu, Siqi Chen, Yiyun Weng, Guangyong Chen
Summary: This study investigates the association between malnutrition and 6-month outcomes in acute ischemic stroke patients with or without intravenous thrombolysis. The results show a significant association between malnutrition and poor functional outcome.
Article
Nutrition & Dietetics
Ainoa Cristina de Oliveira Candido, Felipe Silva Neves, Vanessa Sequeira Fontes, Adriana Soares Torres Melo, Eliane Rodrigues de Faria, Michele Pereira Netto, Renata Maria Souza Oliveira, George Luiz Lins Machado-Coelho, Ana Paula Carlos Candido
Summary: This study investigated the frequency of breakfast consumption and its associations with the consumption of food at different degrees of industrial processing and with overweight indicators in Brazilian adolescents. The results showed that 20% of adolescents skipped breakfast and 46% of their caloric intake came from ultra-processed foods. Skipping breakfast was associated with increased consumption of ultra-processed foods, higher BMI-for-age, and higher body fat percentage.
