A noncatalytic function of the ligation complex during nonhomologous end joining

Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination

(2012) Zhengping Shao et al.   DNA REPAIR

XRCC4's interaction with XLF is required for coding (but not signal) end joining

(2012) S. Roy et al.   NUCLEIC ACIDS RESEARCH

A human XRCC4–XLF complex bridges DNA

(2012) Sara N. Andres et al.   NUCLEIC ACIDS RESEARCH

Live cell imaging of XLF and XRCC4 reveals a novel view of protein assembly in the non-homologous end-joining pathway

(2011) Ken-ichi Yano et al.   CELL CYCLE

Electron microscopy visualization of DNA–protein complexes formed by Ku and DNA ligase IV

(2011) Patricia Grob et al.   DNA REPAIR

Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF

(2011) Ken-ichi Yano et al.   FEBS LETTERS

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Inhibition of Homologous Recombination by DNA-Dependent Protein Kinase Requires Kinase Activity, Is Titratable, and Is Modulated by Autophosphorylation

(2011) J. A. Neal et al.   MOLECULAR AND CELLULAR BIOLOGY

Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies

(2011) Edward P. Morris et al.   NUCLEIC ACIDS RESEARCH

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks

(2011) Qiao Cheng et al.   NUCLEIC ACIDS RESEARCH

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Cell nonhomologous end joining capacity controls SAF-A phosphorylation by DNA-PK in response to DNA double-strand breaks inducers

(2010) Sébastien Britton et al.   CELL CYCLE

A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation

(2010) Tracey A. Dobbs et al.   DNA REPAIR

TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends

(2010) Oriane Bombarde et al.   EMBO JOURNAL

Yeast Nej1 Is a Key Participant in the Initial End Binding and Final Ligation Steps of Nonhomologous End Joining

(2010) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Modes of Interaction between XRCC4 and Polynucleotide Kinase/Phosphatase

(2010) Rajam S. Mani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination

(2010) Anne Bothmer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

(2010) Shan Zha et al.   NATURE

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4–ligase IV during chromosomal translocation formation

(2010) Deniz Simsek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

Repairing DNA double-strand breaks by the prokaryotic non-homologous end-joining pathway

(2009) Nigel C. Brissett et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

DNA Repair in Mammalian Cells

(2009) B. Pardo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex

(2009) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4

(2009) P.-Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases λ and μ for nonhomologous end joining in human whole-cell extracts

(2009) Konstantin Akopiants et al.   NUCLEIC ACIDS RESEARCH

The endless tale of non-homologous end-joining

(2008) Eric Weterings et al.   CELL RESEARCH

A Biochemically Defined System for Coding Joint Formation in V(D)J Recombination

(2008) Haihui Lu et al.   MOLECULAR CELL

Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF

(2008) Sumithra Jayaram et al.   NUCLEIC ACIDS RESEARCH

XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation

(2008) Enriqueta Riballo et al.   NUCLEIC ACIDS RESEARCH